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Items: 1 to 20 of 119

1.

A dynamic G-quadruplex region regulates the HIV-1 long terminal repeat promoter.

Perrone R, Nadai M, Frasson I, Poe JA, Butovskaya E, Smithgall TE, Palumbo M, Palù G, Richter SN.

J Med Chem. 2013 Aug 22;56(16):6521-30. doi: 10.1021/jm400914r. Epub 2013 Aug 6.

PMID:
23865750
2.

Structure and possible function of a G-quadruplex in the long terminal repeat of the proviral HIV-1 genome.

De Nicola B, Lech CJ, Heddi B, Regmi S, Frasson I, Perrone R, Richter SN, Phan AT.

Nucleic Acids Res. 2016 Jul 27;44(13):6442-51. doi: 10.1093/nar/gkw432. Epub 2016 Jun 13.

PMID:
27298260
3.

Synthesis, Binding and Antiviral Properties of Potent Core-Extended Naphthalene Diimides Targeting the HIV-1 Long Terminal Repeat Promoter G-Quadruplexes.

Perrone R, Doria F, Butovskaya E, Frasson I, Botti S, Scalabrin M, Lago S, Grande V, Nadai M, Freccero M, Richter SN.

J Med Chem. 2015 Dec 24;58(24):9639-52. doi: 10.1021/acs.jmedchem.5b01283. Epub 2015 Dec 8.

PMID:
26599611
4.

Nucleolin stabilizes G-quadruplex structures folded by the LTR promoter and silences HIV-1 viral transcription.

Tosoni E, Frasson I, Scalabrin M, Perrone R, Butovskaya E, Nadai M, Palù G, Fabris D, Richter SN.

Nucleic Acids Res. 2015 Oct 15;43(18):8884-97. doi: 10.1093/nar/gkv897. Epub 2015 Sep 9.

PMID:
26354862
5.

Anti-HIV-1 activity of the G-quadruplex ligand BRACO-19.

Perrone R, Butovskaya E, Daelemans D, Palù G, Pannecouque C, Richter SN.

J Antimicrob Chemother. 2014 Dec;69(12):3248-58. doi: 10.1093/jac/dku280. Epub 2014 Aug 6.

PMID:
25103489
7.

U3 region in the HIV-1 genome adopts a G-quadruplex structure in its RNA and DNA sequence.

Piekna-Przybylska D, Sullivan MA, Sharma G, Bambara RA.

Biochemistry. 2014 Apr 29;53(16):2581-93. doi: 10.1021/bi4016692. Epub 2014 Apr 15.

PMID:
24735378
8.

Formation of a unique cluster of G-quadruplex structures in the HIV-1 Nef coding region: implications for antiviral activity.

Perrone R, Nadai M, Poe JA, Frasson I, Palumbo M, Palù G, Smithgall TE, Richter SN.

PLoS One. 2013 Aug 27;8(8):e73121. doi: 10.1371/journal.pone.0073121. eCollection 2013.

PMID:
24015290
9.

Formation of a unique end-to-end stacked pair of G-quadruplexes in the hTERT core promoter with implications for inhibition of telomerase by G-quadruplex-interactive ligands.

Palumbo SL, Ebbinghaus SW, Hurley LH.

J Am Chem Soc. 2009 Aug 12;131(31):10878-91. doi: 10.1021/ja902281d.

PMID:
19601575
10.

Sp1 and related factors fail to interact with the NF-kappaB-proximal G/C box in the LTR of a replication competent, brain-derived strain of HIV-1 (YU-2).

Millhouse S, Krebs FC, Yao J, McAllister JJ, Conner J, Ross H, Wigdahl B.

J Neurovirol. 1998 Jun;4(3):312-23.

PMID:
9639074
11.

Drastic decrease of transcription activity due to hypermutated long terminal repeat (LTR) region in different HIV-1 subtypes and recombinants.

de Arellano ER, Alcamí J, López M, Soriano V, Holguín A.

Antiviral Res. 2010 Nov;88(2):152-9. doi: 10.1016/j.antiviral.2010.08.007. Epub 2010 Aug 14.

PMID:
20713090
12.

Structures, folding patterns, and functions of intramolecular DNA G-quadruplexes found in eukaryotic promoter regions.

Qin Y, Hurley LH.

Biochimie. 2008 Aug;90(8):1149-71. doi: 10.1016/j.biochi.2008.02.020. Epub 2008 Feb 29. Review.

PMID:
18355457
13.

Solution structure of the major G-quadruplex formed in the human VEGF promoter in K+: insights into loop interactions of the parallel G-quadruplexes.

Agrawal P, Hatzakis E, Guo K, Carver M, Yang D.

Nucleic Acids Res. 2013 Dec;41(22):10584-92. doi: 10.1093/nar/gkt784. Epub 2013 Sep 4.

PMID:
24005038
14.
15.

Functional differences between the long terminal repeat transcriptional promoters of human immunodeficiency virus type 1 subtypes A through G.

Jeeninga RE, Hoogenkamp M, Armand-Ugon M, de Baar M, Verhoef K, Berkhout B.

J Virol. 2000 Apr;74(8):3740-51.

PMID:
10729149
16.

Self-organization of G-quadruplex structures in the hTERT core promoter stabilized by polyaminic side chain perylene derivatives.

Micheli E, Martufi M, Cacchione S, De Santis P, Savino M.

Biophys Chem. 2010 Dec;153(1):43-53. doi: 10.1016/j.bpc.2010.10.003. Epub 2010 Oct 13.

PMID:
21036459
17.

Epstein-Barr virus nuclear antigen 2 transactivates the long terminal repeat of human immunodeficiency virus type 1.

Scala G, Quinto I, Ruocco MR, Mallardo M, Ambrosino C, Squitieri B, Tassone P, Venuta S.

J Virol. 1993 May;67(5):2853-61.

PMID:
8386279
18.

Selective recognition of a DNA G-quadruplex by an engineered antibody.

Fernando H, Rodriguez R, Balasubramanian S.

Biochemistry. 2008 Sep 9;47(36):9365-71. doi: 10.1021/bi800983u. Epub 2008 Aug 15.

PMID:
18702511
19.

Long terminal repeat promoter/enhancer activity of different subtypes of HIV type 1.

Naghavi MH, Schwartz S, Sönnerborg A, Vahlne A.

AIDS Res Hum Retroviruses. 1999 Sep 20;15(14):1293-303.

PMID:
10505678
20.

Genotypic and phenotypic heterogeneity in the U3R region of HIV type 1 subtype C.

Mates JM, Kumar SB, Bazan J, Mefford M, Voronkin I, Handelman S, Mwapasa V, Ackerman W 4th, Janies D, Kwiek JJ.

AIDS Res Hum Retroviruses. 2014 Jan;30(1):102-12. doi: 10.1089/AID.2013.0026. Epub 2013 Aug 12.

PMID:
23826737

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