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Items: 1 to 20 of 101

1.

Screening bicyclic peptide libraries for protein-protein interaction inhibitors: discovery of a tumor necrosis factor-α antagonist.

Lian W, Upadhyaya P, Rhodes CA, Liu Y, Pei D.

J Am Chem Soc. 2013 Aug 14;135(32):11990-5. doi: 10.1021/ja405106u. Epub 2013 Aug 1.

2.

Bicyclic peptide inhibitor reveals large contact interface with a protease target.

Angelini A, Cendron L, Chen S, Touati J, Winter G, Zanotti G, Heinis C.

ACS Chem Biol. 2012 May 18;7(5):817-21. doi: 10.1021/cb200478t. Epub 2012 Feb 15.

PMID:
22304751
3.
4.

Screening of tumor necrosis factor-alpha-binding peptides by phage display peptide library.

Guo HP, Luo HB, Liu YJ, Zhu P, Fu N.

Di Yi Jun Yi Da Xue Xue Bao. 2002 Jul;22(7):597-9.

PMID:
12376284
5.
6.

Bicyclic peptide ligands pulled out of cysteine-rich peptide libraries.

Chen S, Rentero Rebollo I, Buth SA, Morales-Sanfrutos J, Touati J, Leiman PG, Heinis C.

J Am Chem Soc. 2013 May 1;135(17):6562-9. doi: 10.1021/ja400461h. Epub 2013 Apr 17.

PMID:
23560397
7.

Targeting diverse protein-protein interaction interfaces with α/β-peptides derived from the Z-domain scaffold.

Checco JW, Kreitler DF, Thomas NC, Belair DG, Rettko NJ, Murphy WL, Forest KT, Gellman SH.

Proc Natl Acad Sci U S A. 2015 Apr 14;112(15):4552-7. doi: 10.1073/pnas.1420380112. Epub 2015 Mar 30.

8.

Hydrostatin-TL1, an Anti-Inflammatory Active Peptide from the Venom Gland of Hydrophis cyanocinctus in the South China Sea.

Wang N, Huang Y, Li A, Jiang H, Wang J, Li J, Qiu L, Li K, Lu Y.

Int J Mol Sci. 2016 Nov 22;17(11). pii: E1940.

9.
10.

Highly Constrained Bicyclic Scaffolds for the Discovery of Protease-Stable Peptides via mRNA Display.

Hacker DE, Hoinka J, Iqbal ES, Przytycka TM, Hartman MC.

ACS Chem Biol. 2017 Mar 17;12(3):795-804. doi: 10.1021/acschembio.6b01006. Epub 2017 Feb 1.

PMID:
28146347
11.

A novel small-molecule tumor necrosis factor α inhibitor attenuates inflammation in a hepatitis mouse model.

Ma L, Gong H, Zhu H, Ji Q, Su P, Liu P, Cao S, Yao J, Jiang L, Han M, Ma X, Xiong D, Luo HR, Wang F, Zhou J, Xu Y.

J Biol Chem. 2014 May 2;289(18):12457-66. doi: 10.1074/jbc.M113.521708. Epub 2014 Mar 14.

12.

Subunit disassembly and inhibition of TNFα by a semi-synthetic bicyclic peptide.

Luzi S, Kondo Y, Bernard E, Stadler LK, Vaysburd M, Winter G, Holliger P.

Protein Eng Des Sel. 2015 Feb;28(2):45-52. doi: 10.1093/protein/gzu055.

13.

A metal-based inhibitor of tumor necrosis factor-α.

Leung CH, Zhong HJ, Yang H, Cheng Z, Chan DS, Ma VP, Abagyan R, Wong CY, Ma DL.

Angew Chem Int Ed Engl. 2012 Sep 3;51(36):9010-4. doi: 10.1002/anie.201202937. Epub 2012 Jul 13.

PMID:
22807261
14.

Comprehensive peptidomimetic libraries targeting protein-protein interactions.

Whitby LR, Boger DL.

Acc Chem Res. 2012 Oct 16;45(10):1698-709. doi: 10.1021/ar300025n. Epub 2012 Jul 16.

15.

Rapid Optimization of Mcl-1 Inhibitors using Stapled Peptide Libraries Including Non-Natural Side Chains.

Rezaei Araghi R, Ryan JA, Letai A, Keating AE.

ACS Chem Biol. 2016 May 20;11(5):1238-44. doi: 10.1021/acschembio.5b01002. Epub 2016 Feb 19.

16.

Structure-function relationship of tumor necrosis factor (TNF) and its receptor interaction based on 3D structural analysis of a fully active TNFR1-selective TNF mutant.

Mukai Y, Shibata H, Nakamura T, Yoshioka Y, Abe Y, Nomura T, Taniai M, Ohta T, Ikemizu S, Nakagawa S, Tsunoda S, Kamada H, Yamagata Y, Tsutsumi Y.

J Mol Biol. 2009 Jan 30;385(4):1221-9. doi: 10.1016/j.jmb.2008.11.053. Epub 2008 Dec 6.

PMID:
19084540
17.

A class of small molecules that inhibit TNFalpha-induced survival and death pathways via prevention of interactions between TNFalphaRI, TRADD, and RIP1.

Gururaja TL, Yung S, Ding R, Huang J, Zhou X, McLaughlin J, Daniel-Issakani S, Singh R, Cooper RD, Payan DG, Masuda ES, Kinoshita T.

Chem Biol. 2007 Oct;14(10):1105-18.

18.

Reduced tumor necrosis factor signaling in primary human fibroblasts containing a tumor necrosis factor receptor superfamily 1A mutant.

Siebert S, Amos N, Fielding CA, Wang EC, Aksentijevich I, Williams BD, Brennan P.

Arthritis Rheum. 2005 Apr;52(4):1287-92.

19.

Soluble Tumor Necrosis Factor Alpha Promotes Retinal Ganglion Cell Death in Glaucoma via Calcium-Permeable AMPA Receptor Activation.

Cueva Vargas JL, Osswald IK, Unsain N, Aurousseau MR, Barker PA, Bowie D, Di Polo A.

J Neurosci. 2015 Sep 2;35(35):12088-102. doi: 10.1523/JNEUROSCI.1273-15.2015.

20.

Selection of a novel and highly specific tumor necrosis factor alpha (TNFalpha) antagonist: insight from the crystal structure of the antagonist-TNFalpha complex.

Byla P, Andersen MH, Holtet TL, Jacobsen H, Munch M, Gad HH, Thøgersen HC, Hartmann R.

J Biol Chem. 2010 Apr 16;285(16):12096-100. doi: 10.1074/jbc.M109.063305. Epub 2010 Feb 23.

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