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Cell cycle checkpoint abnormalities during dementia: A plausible association with the loss of protection against oxidative stress in Alzheimer's disease [corrected].

Katsel P, Tan W, Fam P, Purohit DP, Haroutunian V.

PLoS One. 2013 Jul 5;8(7):e68361. doi: 10.1371/journal.pone.0068361. Print 2013. Erratum in: PLoS One. 2013;8(7). doi:10.1371/annotation/59ecb64c-1f53-4d8a-903c-2f835e78bd13.


Transcriptional alterations related to neuropathology and clinical manifestation of Alzheimer's disease.

Silva AR, Grinberg LT, Farfel JM, Diniz BS, Lima LA, Silva PJ, Ferretti RE, Rocha RM, Filho WJ, Carraro DM, Brentani H.

PLoS One. 2012;7(11):e48751. doi: 10.1371/journal.pone.0048751. Epub 2012 Nov 7.


Repair of oxidative DNA damage, cell-cycle regulation and neuronal death may influence the clinical manifestation of Alzheimer's disease.

Silva AR, Santos AC, Farfel JM, Grinberg LT, Ferretti RE, Campos AH, Cunha IW, Begnami MD, Rocha RM, Carraro DM, de Bragança Pereira CA, Jacob-Filho W, Brentani H.

PLoS One. 2014 Jun 17;9(6):e99897. doi: 10.1371/journal.pone.0099897. eCollection 2014.


Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer's disease.

Wang M, Roussos P, McKenzie A, Zhou X, Kajiwara Y, Brennand KJ, De Luca GC, Crary JF, Casaccia P, Buxbaum JD, Ehrlich M, Gandy S, Goate A, Katsel P, Schadt E, Haroutunian V, Zhang B.

Genome Med. 2016 Nov 1;8(1):104.


Selective impairment of p53-mediated cell death in fibroblasts from sporadic Alzheimer's disease patients.

Uberti D, Carsana T, Bernardi E, Rodella L, Grigolato P, Lanni C, Racchi M, Govoni S, Memo M.

J Cell Sci. 2002 Aug 1;115(Pt 15):3131-8.


Nucleic acid oxidation: an early feature of Alzheimer's disease.

Bradley-Whitman MA, Timmons MD, Beckett TL, Murphy MP, Lynn BC, Lovell MA.

J Neurochem. 2014 Jan;128(2):294-304. doi: 10.1111/jnc.12444. Epub 2013 Oct 21.


DNA damage and repair in Alzheimer's disease.

Coppedè F, Migliore L.

Curr Alzheimer Res. 2009 Feb;6(1):36-47. Review.


Temporal cortex synaptophysin mRNA is reduced in Alzheimer's disease and is negatively correlated with the severity of dementia.

Heffernan JM, Eastwood SL, Nagy Z, Sanders MW, McDonald B, Harrison PJ.

Exp Neurol. 1998 Apr;150(2):235-9.


Base excision DNA repair levels in mitochondrial lysates of Alzheimer's disease.

Canugovi C, Shamanna RA, Croteau DL, Bohr VA.

Neurobiol Aging. 2014 Jun;35(6):1293-300. doi: 10.1016/j.neurobiolaging.2014.01.004. Epub 2014 Jan 8.


Association of ApoE and LRP mRNA levels with dementia and AD neuropathology.

Akram A, Schmeidler J, Katsel P, Hof PR, Haroutunian V.

Neurobiol Aging. 2012 Mar;33(3):628.e1-628.e14. doi: 10.1016/j.neurobiolaging.2011.04.010. Epub 2011 Jun 15.


Early molecular changes in Alzheimer disease: can we catch the disease in its presymptomatic phase?

Wirz KT, Keitel S, Swaab DF, Verhaagen J, Bossers K.

J Alzheimers Dis. 2014;38(4):719-40. doi: 10.3233/JAD-130920. Review.


TIGAR, a p53-inducible regulator of glycolysis and apoptosis.

Bensaad K, Tsuruta A, Selak MA, Vidal MN, Nakano K, Bartrons R, Gottlieb E, Vousden KH.

Cell. 2006 Jul 14;126(1):107-20.


Cytokine gene expression as a function of the clinical progression of Alzheimer disease dementia.

Luterman JD, Haroutunian V, Yemul S, Ho L, Purohit D, Aisen PS, Mohs R, Pasinetti GM.

Arch Neurol. 2000 Aug;57(8):1153-60.


Redox regulation of heat shock protein expression in aging and neurodegenerative disorders associated with oxidative stress: a nutritional approach.

Calabrese V, Scapagnini G, Colombrita C, Ravagna A, Pennisi G, Giuffrida Stella AM, Galli F, Butterfield DA.

Amino Acids. 2003 Dec;25(3-4):437-44. Epub 2003 Nov 7. Review.


Gene expression signatures but not cell cycle checkpoint functions distinguish AT carriers from normal individuals.

Zhang L, Simpson DA, Innes CL, Chou J, Bushel PR, Paules RS, Kaufmann WK, Zhou T.

Physiol Genomics. 2013 Oct 1;45(19):907-16. doi: 10.1152/physiolgenomics.00064.2013. Epub 2013 Aug 13.


TIGAR induces p53-mediated cell-cycle arrest by regulation of RB-E2F1 complex.

Madan E, Gogna R, Kuppusamy P, Bhatt M, Pati U, Mahdi AA.

Br J Cancer. 2012 Jul 24;107(3):516-26. doi: 10.1038/bjc.2012.260. Epub 2012 Jul 10.

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