Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 112

1.

Label free fragment screening using surface plasmon resonance as a tool for fragment finding - analyzing parkin, a difficult CNS target.

Regnström K, Yan J, Nguyen L, Callaway K, Yang Y, Diep L, Xing W, Adhikari A, Beroza P, Hom RK, Riley B, Rudolph D, Jobling MF, Baker J, Johnston J, Konradi A, Bova MP, Artis DR.

PLoS One. 2013 Jul 5;8(7):e66879. doi: 10.1371/journal.pone.0066879. Print 2013. Erratum in: PLoS One. 2013;8(7). doi:10.1371/annotation/590bbe38-3a12-45bd-bc5d-83b766c968b3. Artis, Rick D [corrected to Artis, Dean R].

2.

Target immobilization as a strategy for NMR-based fragment screening: comparison of TINS, STD, and SPR for fragment hit identification.

Kobayashi M, Retra K, Figaroa F, Hollander JG, Ab E, Heetebrij RJ, Irth H, Siegal G.

J Biomol Screen. 2010 Sep;15(8):978-89. doi: 10.1177/1087057110375614.

PMID:
20817886
3.

SPR-based fragment screening: advantages and applications.

Neumann T, Junker HD, Schmidt K, Sekul R.

Curr Top Med Chem. 2007;7(16):1630-42. Review.

PMID:
17979772
4.

[Fragment screening using surface plasmon resonance optical biosensor technology].

Miura T.

Yakugaku Zasshi. 2010 Mar;130(3):341-8. Japanese.

5.

From experimental design to validated hits a comprehensive walk-through of fragment lead identification using surface plasmon resonance.

Giannetti AM.

Methods Enzymol. 2011;493:169-218. doi: 10.1016/B978-0-12-381274-2.00008-X.

PMID:
21371592
6.

A comparative study of fragment screening methods on the p38α kinase: new methods, new insights.

Pollack SJ, Beyer KS, Lock C, Müller I, Sheppard D, Lipkin M, Hardick D, Blurton P, Leonard PM, Hubbard PA, Todd D, Richardson CM, Ahrens T, Baader M, Hafenbradl DO, Hilyard K, Bürli RW.

J Comput Aided Mol Des. 2011 Jul;25(7):677-87. doi: 10.1007/s10822-011-9454-9. Epub 2011 Jul 6.

7.

Fragment-based drug discovery using a multidomain, parallel MD-MM/PBSA screening protocol.

Zhu T, Lee H, Lei H, Jones C, Patel K, Johnson ME, Hevener KE.

J Chem Inf Model. 2013 Mar 25;53(3):560-72. doi: 10.1021/ci300502h. Epub 2013 Mar 14.

8.

A Fragment-Based Ligand Screen Against Part of a Large Protein Machine: The ND1 Domains of the AAA+ ATPase p97/VCP.

Chimenti MS, Bulfer SL, Neitz RJ, Renslo AR, Jacobson MP, James TL, Arkin MR, Kelly MJ.

J Biomol Screen. 2015 Jul;20(6):788-800. doi: 10.1177/1087057115570550. Epub 2015 Feb 17.

PMID:
25690569
9.

Identification of B. anthracis N(5)-carboxyaminoimidazole ribonucleotide mutase (PurE) active site binding compounds via fragment library screening.

Lei H, Jones C, Zhu T, Patel K, Wolf NM, Fung LW, Lee H, Johnson ME.

Bioorg Med Chem. 2016 Feb 15;24(4):596-605. doi: 10.1016/j.bmc.2015.12.029. Epub 2015 Dec 18.

PMID:
26740153
10.

Fragment screening by SPR and advanced application to GPCRs.

Shepherd CA, Hopkins AL, Navratilova I.

Prog Biophys Mol Biol. 2014 Nov-Dec;116(2-3):113-23. doi: 10.1016/j.pbiomolbio.2014.09.008. Epub 2014 Oct 6. Review.

11.

High-throughput fragment screening by affinity LC-MS.

Duong-Thi MD, Bergström M, Fex T, Isaksson R, Ohlson S.

J Biomol Screen. 2013 Feb;18(2):160-71. doi: 10.1177/1087057112459271. Epub 2012 Sep 13.

PMID:
22983162
12.

Developments in SPR Fragment Screening.

Chavanieu A, Pugnière M.

Expert Opin Drug Discov. 2016;11(5):489-99. doi: 10.1517/17460441.2016.1160888. Epub 2016 Mar 21. Review.

PMID:
26948323
13.

Emerging role of surface plasmon resonance in fragment-based drug discovery.

Navratilova I, Hopkins AL.

Future Med Chem. 2011 Oct;3(14):1809-20. doi: 10.4155/fmc.11.128. Review.

PMID:
22004086
14.

Biosensor-based small molecule fragment screening with biolayer interferometry.

Wartchow CA, Podlaski F, Li S, Rowan K, Zhang X, Mark D, Huang KS.

J Comput Aided Mol Des. 2011 Jul;25(7):669-76. doi: 10.1007/s10822-011-9439-8. Epub 2011 Jun 10.

PMID:
21660516
15.

Saturation transfer difference NMR for fragment screening.

Begley DW, Moen SO, Pierce PG, Zartler ER.

Curr Protoc Chem Biol. 2013;5(4):251-68. doi: 10.1002/9780470559277.ch130118.

PMID:
24391096
16.

SPR imaging for high throughput, label-free interaction analysis.

Lausted C, Hu Z, Hood L, Campbell CT.

Comb Chem High Throughput Screen. 2009 Sep;12(8):741-51. Epub 2009 Sep 1. Review.

PMID:
19531009
17.

Applications of Biophysics in High-Throughput Screening Hit Validation.

Genick CC, Barlier D, Monna D, Brunner R, Bé C, Scheufler C, Ottl J.

J Biomol Screen. 2014 Jun;19(5):707-14. doi: 10.1177/1087057114529462. Epub 2014 Apr 2.

PMID:
24695619
18.

Surface plasmon resonance spectroscopy for characterisation of membrane protein-ligand interactions and its potential for drug discovery.

Patching SG.

Biochim Biophys Acta. 2014 Jan;1838(1 Pt A):43-55. doi: 10.1016/j.bbamem.2013.04.028. Epub 2013 May 9. Review.

19.

SPR microscopy and its applications to high-throughput analyses of biomolecular binding events and their kinetics.

Campbell CT, Kim G.

Biomaterials. 2007 May;28(15):2380-92. Epub 2007 Mar 6. Review.

PMID:
17337300
20.

Label-enhanced surface plasmon resonance applied to label-free interaction analysis of small molecules and fragments.

Eng L, Nygren-Babol L, Hanning A.

Anal Biochem. 2016 Oct 1;510:79-87. doi: 10.1016/j.ab.2016.06.008. Epub 2016 Jun 17.

PMID:
27325502

Supplemental Content

Support Center