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Items: 1 to 20 of 97

1.

Improved efficacy of fosmidomycin against Plasmodium and Mycobacterium species by combination with the cell-penetrating peptide octaarginine.

Sparr C, Purkayastha N, Kolesinska B, Gengenbacher M, Amulic B, Matuschewski K, Seebach D, Kamena F.

Antimicrob Agents Chemother. 2013 Oct;57(10):4689-98. doi: 10.1128/AAC.00427-13. Epub 2013 Jul 15.

2.

Fosmidomycin uptake into Plasmodium and Babesia-infected erythrocytes is facilitated by parasite-induced new permeability pathways.

Baumeister S, Wiesner J, Reichenberg A, Hintz M, Bietz S, Harb OS, Roos DS, Kordes M, Friesen J, Matuschewski K, Lingelbach K, Jomaa H, Seeber F.

PLoS One. 2011 May 4;6(5):e19334. doi: 10.1371/journal.pone.0019334.

3.

In vitro and in vivo synergy of fosmidomycin, a novel antimalarial drug, with clindamycin.

Wiesner J, Henschker D, Hutchinson DB, Beck E, Jomaa H.

Antimicrob Agents Chemother. 2002 Sep;46(9):2889-94.

4.

A second target of the antimalarial and antibacterial agent fosmidomycin revealed by cellular metabolic profiling.

Zhang B, Watts KM, Hodge D, Kemp LM, Hunstad DA, Hicks LM, Odom AR.

Biochemistry. 2011 May 3;50(17):3570-7. doi: 10.1021/bi200113y. Epub 2011 Apr 11.

5.

Fosmidomycin for the treatment of malaria.

Wiesner J, Borrmann S, Jomaa H.

Parasitol Res. 2003 Jun;90 Suppl 2:S71-6. Epub 2002 Nov 30. Review.

PMID:
12937969
6.

Apicoplast isoprenoid precursor synthesis and the molecular basis of fosmidomycin resistance in Toxoplasma gondii.

Nair SC, Brooks CF, Goodman CD, Sturm A, McFadden GI, Sundriyal S, Anglin JL, Song Y, Moreno SN, Striepen B.

J Exp Med. 2011 Jul 4;208(7):1547-59. doi: 10.1084/jem.20110039. Epub 2011 Jun 20. Erratum in: J Exp Med. 2012 May 7;209(5):1051. Strurm, Angelika [corrected to Sturm, Angelika].

7.

Resistance to the antimicrobial agent fosmidomycin and an FR900098 prodrug through mutations in the deoxyxylulose phosphate reductoisomerase gene (dxr).

Armstrong CM, Meyers DJ, Imlay LS, Freel Meyers C, Odom AR.

Antimicrob Agents Chemother. 2015 Sep;59(9):5511-9. doi: 10.1128/AAC.00602-15. Epub 2015 Jun 29.

8.

Dxr is essential in Mycobacterium tuberculosis and fosmidomycin resistance is due to a lack of uptake.

Brown AC, Parish T.

BMC Microbiol. 2008 May 20;8:78. doi: 10.1186/1471-2180-8-78.

9.

Prodrugs of reverse fosmidomycin analogues.

Brücher K, Gräwert T, Konzuch S, Held J, Lienau C, Behrendt C, Illarionov B, Maes L, Bacher A, Wittlin S, Mordmüller B, Fischer M, Kurz T.

J Med Chem. 2015 Feb 26;58(4):2025-35. doi: 10.1021/jm5019719. Epub 2015 Feb 12.

PMID:
25633870
10.

Isoprenoid biosynthesis inhibition disrupts Rab5 localization and food vacuolar integrity in Plasmodium falciparum.

Howe R, Kelly M, Jimah J, Hodge D, Odom AR.

Eukaryot Cell. 2013 Feb;12(2):215-23. doi: 10.1128/EC.00073-12. Epub 2012 Dec 7.

11.

DXR inhibition by potent mono- and disubstituted fosmidomycin analogues.

Jansson AM, Więckowska A, Björkelid C, Yahiaoui S, Sooriyaarachchi S, Lindh M, Bergfors T, Dharavath S, Desroses M, Suresh S, Andaloussi M, Nikhil R, Sreevalli S, Srinivasa BR, Larhed M, Jones TA, Karlén A, Mowbray SL.

J Med Chem. 2013 Aug 8;56(15):6190-9. doi: 10.1021/jm4006498. Epub 2013 Jul 17.

PMID:
23819803
12.

Isoprenoid biosynthesis in Plasmodium falciparum.

Guggisberg AM, Amthor RE, Odom AR.

Eukaryot Cell. 2014 Nov;13(11):1348-59. doi: 10.1128/EC.00160-14. Epub 2014 Sep 12. Review.

13.

The isoprenoid-precursor dependence of Plasmodium spp.

van der Meer JY, Hirsch AK.

Nat Prod Rep. 2012 Jul;29(7):721-8. doi: 10.1039/c2np20013a. Epub 2012 May 4. Review.

PMID:
22555616
14.
15.

Fosmidomycin-clindamycin for the treatment of Plasmodium falciparum malaria.

Borrmann S, Issifou S, Esser G, Adegnika AA, Ramharter M, Matsiegui PB, Oyakhirome S, Mawili-Mboumba DP, Missinou MA, Kun JF, Jomaa H, Kremsner PG.

J Infect Dis. 2004 Nov 1;190(9):1534-40. Epub 2004 Sep 21.

PMID:
15478056
16.

Chemical rescue of malaria parasites lacking an apicoplast defines organelle function in blood-stage Plasmodium falciparum.

Yeh E, DeRisi JL.

PLoS Biol. 2011 Aug;9(8):e1001138. doi: 10.1371/journal.pbio.1001138. Epub 2011 Aug 30.

17.

[Evaluation of in vitro antibacterial activity of fosmidomycin and its derivatives].

Shtannikov AV, Sergeeva EE, Biketov SF, Ostrovskiĭ DN.

Antibiot Khimioter. 2007;52(7-8):3-9. Russian.

PMID:
18986018
18.

Synthesis and antimalarial evaluation of prodrugs of novel fosmidomycin analogues.

Faísca Phillips AM, Nogueira F, Murtinheira F, Barros MT.

Bioorg Med Chem Lett. 2015;25(10):2112-6. doi: 10.1016/j.bmcl.2015.03.077. Epub 2015 Mar 31.

PMID:
25881827
19.

The methylerythritol phosphate pathway for isoprenoid biosynthesis in coccidia: presence and sensitivity to fosmidomycin.

Clastre M, Goubard A, Prel A, Mincheva Z, Viaud-Massuart MC, Bout D, Rideau M, Velge-Roussel F, Laurent F.

Exp Parasitol. 2007 Aug;116(4):375-84. Epub 2007 Feb 21.

PMID:
17399705
20.

Assessment of in vitro antimalarial interactions between dihydroartemisinin and fosmidomycin.

Chaijaroenkul W, Pruktal P, Muhamad P, Na-Bangchang K.

Southeast Asian J Trop Med Public Health. 2007 Sep;38(5):791-5.

PMID:
18041293

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