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Items: 1 to 20 of 44

1.

Unpicking neurodegeneration in a dish with human pluripotent stem cells: one cell type at a time.

Bilican B, Serio A, Shaw CE, Maniatis T, Chandran S.

Cell Cycle. 2013 Aug 1;12(15):2339-40. doi: 10.4161/cc.25705. No abstract available.

2.

Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy.

Serio A, Bilican B, Barmada SJ, Ando DM, Zhao C, Siller R, Burr K, Haghi G, Story D, Nishimura AL, Carrasco MA, Phatnani HP, Shum C, Wilmut I, Maniatis T, Shaw CE, Finkbeiner S, Chandran S.

Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4697-702. doi: 10.1073/pnas.1300398110.

3.

Glia as primary drivers of neuropathology in TDP-43 proteinopathies.

Sloan SA, Barres BA.

Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4439-40. doi: 10.1073/pnas.1301608110. No abstract available.

4.

A cellular model for sporadic ALS using patient-derived induced pluripotent stem cells.

Burkhardt MF, Martinez FJ, Wright S, Ramos C, Volfson D, Mason M, Garnes J, Dang V, Lievers J, Shoukat-Mumtaz U, Martinez R, Gai H, Blake R, Vaisberg E, Grskovic M, Johnson C, Irion S, Bright J, Cooper B, Nguyen L, Griswold-Prenner I, Javaherian A.

Mol Cell Neurosci. 2013 Sep;56:355-64. doi: 10.1016/j.mcn.2013.07.007.

5.

Altered astrocytic expression of TDP-43 does not influence motor neuron survival.

Haidet-Phillips AM, Gross SK, Williams T, Tuteja A, Sherman A, Ko M, Jeong YH, Wong PC, Maragakis NJ.

Exp Neurol. 2013 Dec;250:250-9. doi: 10.1016/j.expneurol.2013.10.004.

PMID:
24120466
6.

Lack of TNF-alpha receptor type 2 protects motor neurons in a cellular model of amyotrophic lateral sclerosis and in mutant SOD1 mice but does not affect disease progression.

Tortarolo M, Vallarola A, Lidonnici D, Battaglia E, Gensano F, Spaltro G, Fiordaliso F, Corbelli A, Garetto S, Martini E, Pasetto L, Kallikourdis M, Bonetto V, Bendotti C.

J Neurochem. 2015 Oct;135(1):109-24. doi: 10.1111/jnc.13154.

7.

Motor neuron-astrocyte interactions and levels of Cu,Zn superoxide dismutase in sporadic amyotrophic lateral sclerosis.

O'Reilly SA, Roedica J, Nagy D, Hallewell RA, Alderson K, Marklund SL, Kuby J, Kushner PD.

Exp Neurol. 1995 Feb;131(2):203-10.

PMID:
7895821
8.

Induced pluripotent stem cells from ALS patients for disease modeling.

Richard JP, Maragakis NJ.

Brain Res. 2015 May 14;1607:15-25. doi: 10.1016/j.brainres.2014.09.017. Review.

9.

Motor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosis.

Estes PS, Daniel SG, McCallum AP, Boehringer AV, Sukhina AS, Zwick RA, Zarnescu DC.

Dis Model Mech. 2013 May;6(3):721-33. doi: 10.1242/dmm.010710.

10.

Drug screening for ALS using patient-specific induced pluripotent stem cells.

Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T, Adachi F, Kondo T, Okita K, Asaka I, Aoi T, Watanabe A, Yamada Y, Morizane A, Takahashi J, Ayaki T, Ito H, Yoshikawa K, Yamawaki S, Suzuki S, Watanabe D, Hioki H, Kaneko T, Makioka K, Okamoto K, Takuma H, Tamaoka A, Hasegawa K, Nonaka T, Hasegawa M, Kawata A, Yoshida M, Nakahata T, Takahashi R, Marchetto MC, Gage FH, Yamanaka S, Inoue H.

Sci Transl Med. 2012 Aug 1;4(145):145ra104. doi: 10.1126/scitranslmed.3004052.

11.

Comment on "Drug screening for ALS using patient-specific induced pluripotent stem cells".

Bilican B, Serio A, Barmada SJ, Nishimura AL, Sullivan GJ, Carrasco M, Phatnani HP, Puddifoot CA, Story D, Fletcher J, Park IH, Friedman BA, Daley GQ, Wyllie DJ, Hardingham GE, Wilmut I, Finkbeiner S, Maniatis T, Shaw CE, Chandran S.

Sci Transl Med. 2013 Jun 5;5(188):188le2. doi: 10.1126/scitranslmed.3005065.

12.

Stem cell-derived motor neurons: applications and challenges in amyotrophic lateral sclerosis.

Thonhoff JR, Ojeda L, Wu P.

Curr Stem Cell Res Ther. 2009 Sep;4(3):178-99. Review.

13.

Connexin 43 in astrocytes contributes to motor neuron toxicity in amyotrophic lateral sclerosis.

Almad AA, Doreswamy A, Gross SK, Richard JP, Huo Y, Haughey N, Maragakis NJ.

Glia. 2016 Jul;64(7):1154-69. doi: 10.1002/glia.22989.

PMID:
27083773
15.
16.

A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis.

Barbeito LH, Pehar M, Cassina P, Vargas MR, Peluffo H, Viera L, Estévez AG, Beckman JS.

Brain Res Brain Res Rev. 2004 Dec;47(1-3):263-74. Review.

PMID:
15572176
17.

Direct conversion of patient fibroblasts demonstrates non-cell autonomous toxicity of astrocytes to motor neurons in familial and sporadic ALS.

Meyer K, Ferraiuolo L, Miranda CJ, Likhite S, McElroy S, Renusch S, Ditsworth D, Lagier-Tourenne C, Smith RA, Ravits J, Burghes AH, Shaw PJ, Cleveland DW, Kolb SJ, Kaspar BK.

Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):829-32. doi: 10.1073/pnas.1314085111.

18.

Response to comment on "Drug screening for ALS using patient-specific induced pluripotent stem cells".

Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T, Adachi F, Kondo T, Okita K, Asaka I, Aoi T, Watanabe A, Yamada Y, Morizane A, Takahashi J, Ayaki T, Ito H, Yoshikawa K, Yamawaki S, Suzuki S, Watanabe D, Hioki H, Kaneko T, Makioka K, Okamoto K, Takuma H, Tamaoka A, Hasegawa K, Nonaka T, Hasegawa M, Kawata A, Yoshida M, Nakahata T, Takahashi R, Marchetto MC, Gage FH, Yamanaka S, Inoue H.

Sci Transl Med. 2013 Jun 5;5(188):188lr2. doi: 10.1126/scitranslmed.3005697.

19.

Human TDP-43 and FUS selectively affect motor neuron maturation and survival in a murine cell model of ALS by non-cell-autonomous mechanisms.

Wächter N, Storch A, Hermann A.

Amyotroph Lateral Scler Frontotemporal Degener. 2015;16(7-8):431-41. doi: 10.3109/21678421.2015.1055275.

PMID:
26174443
20.

Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability.

Bilican B, Serio A, Barmada SJ, Nishimura AL, Sullivan GJ, Carrasco M, Phatnani HP, Puddifoot CA, Story D, Fletcher J, Park IH, Friedman BA, Daley GQ, Wyllie DJ, Hardingham GE, Wilmut I, Finkbeiner S, Maniatis T, Shaw CE, Chandran S.

Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5803-8. doi: 10.1073/pnas.1202922109.

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