Format
Sort by

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 134

1.

Tetrazole and triazole as bioisosteres of carboxylic acid: discovery of diketo tetrazoles and diketo triazoles as anti-HCV agents.

Song WH, Liu MM, Zhong DW, Zhu YL, Bosscher M, Zhou L, Ye DY, Yuan ZH.

Bioorg Med Chem Lett. 2013 Aug 15;23(16):4528-31. doi: 10.1016/j.bmcl.2013.06.045.

PMID:
23856047
2.

Anti-cancer and anti-hepatitis C virus NS5B polymerase activity of etodolac 1,2,4-triazoles.

Çıkla-Süzgün P, Kaushik-Basu N, Basu A, Arora P, Talele TT, Durmaz I, Çetin-Atalay R, Küçükgüzel ŞG.

J Enzyme Inhib Med Chem. 2015;30(5):778-85. doi: 10.3109/14756366.2014.971780.

PMID:
25676325
3.

Arylethynyltriazole acyclonucleosides inhibit hepatitis C virus replication.

Zhu R, Wang M, Xia Y, Qu F, Neyts J, Peng L.

Bioorg Med Chem Lett. 2008 Jun 1;18(11):3321-7. doi: 10.1016/j.bmcl.2008.04.026.

PMID:
18445526
4.

Design and synthesis of lactam-thiophene carboxylic acids as potent hepatitis C virus polymerase inhibitors.

Barnes-Seeman D, Boiselle C, Capacci-Daniel C, Chopra R, Hoffmaster K, Jones CT, Kato M, Lin K, Ma S, Pan G, Shu L, Wang J, Whiteman L, Xu M, Zheng R, Fu J.

Bioorg Med Chem Lett. 2014 Aug 15;24(16):3979-85. doi: 10.1016/j.bmcl.2014.06.031.

PMID:
24986660
5.

C-6 aryl substituted 4-quinolone-3-carboxylic acids as inhibitors of hepatitis C virus.

Chen YL, Zacharias J, Vince R, Geraghty RJ, Wang Z.

Bioorg Med Chem. 2012 Aug 1;20(15):4790-800. doi: 10.1016/j.bmc.2012.05.066.

PMID:
22748708
6.

2-(3-Thienyl)-5,6-dihydroxypyrimidine-4-carboxylic acids as inhibitors of HCV NS5B RdRp.

Pacini B, Avolio S, Ercolani C, Koch U, Migliaccio G, Narjes F, Pacini L, Tomei L, Harper S.

Bioorg Med Chem Lett. 2009 Nov 1;19(21):6245-9. doi: 10.1016/j.bmcl.2009.06.106.

PMID:
19800789
7.

Synthesis and anti-hepatitis C virus activity of novel ethyl 1H-indole-3-carboxylates in vitro.

Sellitto G, Faruolo A, de Caprariis P, Altamura S, Paonessa G, Ciliberto G.

Bioorg Med Chem. 2010 Aug 15;18(16):6143-8. doi: 10.1016/j.bmc.2010.06.058.

PMID:
20638289
8.

Synthesis and SAR optimization of diketo acid pharmacophore for HCV NS5B polymerase inhibition.

Bhatt A, Gurukumar KR, Basu A, Patel MR, Kaushik-Basu N, Talele TT.

Eur J Med Chem. 2011 Oct;46(10):5138-45. doi: 10.1016/j.ejmech.2011.08.028.

9.

Bioisosteres of arecoline: 1,2,3,6-tetrahydro-5-pyridyl-substituted and 3-piperidyl-substituted derivatives of tetrazoles and 1,2,3-triazoles. Synthesis and muscarinic activity.

Moltzen EK, Pedersen H, Bøgesø KP, Meier E, Frederiksen K, Sánchez C, Løve Lembøl H.

J Med Chem. 1994 Nov 25;37(24):4085-99.

PMID:
7990109
10.

Structure based medicinal chemistry approach to develop 4-methyl-7-deazaadenine carbocyclic nucleosides as anti-HCV agent.

Thiyagarajan A, Salim MT, Balaraju T, Bal C, Baba M, Sharon A.

Bioorg Med Chem Lett. 2012 Dec 15;22(24):7742-7. doi: 10.1016/j.bmcl.2012.09.072.

PMID:
23122860
11.

Design and synthesis of low molecular weight compounds with complement inhibition activity.

Master HE, Khan SI, Poojari KA.

Bioorg Med Chem. 2005 Aug 15;13(16):4891-9.

PMID:
15978815
12.

Novel 1,2,4-triazole and imidazole derivatives of L-ascorbic and imino-ascorbic acid: synthesis, anti-HCV and antitumor activity evaluations.

Wittine K, Stipković Babić M, Makuc D, Plavec J, Kraljević Pavelić S, Sedić M, Pavelić K, Leyssen P, Neyts J, Balzarini J, Mintas M.

Bioorg Med Chem. 2012 Jun 1;20(11):3675-85. doi: 10.1016/j.bmc.2012.01.054.

PMID:
22555152
13.

S-aryltriazole acyclonucleosides: synthesis and biological evaluation against hepatitis C virus.

Liu Y, Xia Y, Li W, Cong M, Maggiani A, Leyssen P, Qu F, Neyts J, Peng L.

Bioorg Med Chem Lett. 2010 Jun 15;20(12):3610-3. doi: 10.1016/j.bmcl.2010.04.115.

PMID:
20483607
14.

7-O-Arylmethylgalangin as a novel scaffold for anti-HCV agents.

Lee HS, Park KS, Lee C, Lee B, Kim DE, Chong Y.

Bioorg Med Chem Lett. 2010 Oct 1;20(19):5709-12. doi: 10.1016/j.bmcl.2010.08.012.

PMID:
20797857
15.

Discovery of Metal Ions Chelator Quercetin Derivatives with Potent Anti-HCV Activities.

Zhong D, Liu M, Cao Y, Zhu Y, Bian S, Zhou J, Wu F, Ryu KC, Zhou L, Ye D.

Molecules. 2015 Apr 16;20(4):6978-99. doi: 10.3390/molecules20046978.

16.

Novel anilinocoumarin derivatives as agents against hepatitis C virus by the induction of IFN-mediated antiviral responses.

Peng HK, Chen WC, Lee JC, Yang SY, Tzeng CC, Lin YT, Yang SC.

Org Biomol Chem. 2013 Mar 21;11(11):1858-66. doi: 10.1039/c2ob26860d.

PMID:
23377187
17.

Discovery of 2-iminobenzimidazoles as potent hepatitis C virus inhibitors with a novel mechanism of action.

Windisch MP, Jo S, Kim HY, Kim SH, Kim K, Kong S, Jeong H, Ahn S, No Z, Hwang JY.

Eur J Med Chem. 2014 May 6;78:35-42. doi: 10.1016/j.ejmech.2014.03.030.

PMID:
24675178
18.

The design, synthesis, and antiviral activity of 4'-azidocytidine analogues against hepatitis C virus replication: the discovery of 4'-azidoarabinocytidine.

Smith DB, Kalayanov G, Sund C, Winqvist A, Pinho P, Maltseva T, Morisson V, Leveque V, Rajyaguru S, Le Pogam S, Najera I, Benkestock K, Zhou XX, Maag H, Cammack N, Martin JA, Swallow S, Johansson NG, Klumpp K, Smith M.

J Med Chem. 2009 Jan 8;52(1):219-23. doi: 10.1021/jm800981y.

PMID:
19055482
19.

2-hydroxy-1-oxo-1,2-dihydroisoquinoline-3-carboxylic acid with inbuilt β-N-hydroxy-γ-keto-acid pharmacophore as HCV NS5B polymerase inhibitors.

Deore RR, Chen GS, Chen CS, Chang PT, Chuang MH, Chern TR, Wang HC, Chern JW.

Curr Med Chem. 2012;19(4):613-24. Review.

PMID:
22204334
20.

Discovery of GS-9451: an acid inhibitor of the hepatitis C virus NS3/4A protease.

Sheng XC, Appleby T, Butler T, Cai R, Chen X, Cho A, Clarke MO, Cottell J, Delaney WE 4th, Doerffler E, Link J, Ji M, Pakdaman R, Pyun HJ, Wu Q, Xu J, Kim CU.

Bioorg Med Chem Lett. 2012 Apr 1;22(7):2629-34. doi: 10.1016/j.bmcl.2012.01.017.

PMID:
22366653
Items per page

Supplemental Content

Support Center