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Histone deacetylase 7 promotes Toll-like receptor 4-dependent proinflammatory gene expression in macrophages.

Shakespear MR, Hohenhaus DM, Kelly GM, Kamal NA, Gupta P, Labzin LI, Schroder K, Garceau V, Barbero S, Iyer A, Hume DA, Reid RC, Irvine KM, Fairlie DP, Sweet MJ.

J Biol Chem. 2013 Aug 30;288(35):25362-74. doi: 10.1074/jbc.M113.496281. Epub 2013 Jul 12.


Histone deacetylase 7 associates with hypoxia-inducible factor 1alpha and increases transcriptional activity.

Kato H, Tamamizu-Kato S, Shibasaki F.

J Biol Chem. 2004 Oct 1;279(40):41966-74. Epub 2004 Jul 26.


Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS.

Halili MA, Andrews MR, Labzin LI, Schroder K, Matthias G, Cao C, Lovelace E, Reid RC, Le GT, Hume DA, Irvine KM, Matthias P, Fairlie DP, Sweet MJ.

J Leukoc Biol. 2010 Jun;87(6):1103-14. doi: 10.1189/jlb.0509363. Epub 2010 Mar 3.


LPS regulates proinflammatory gene expression in macrophages by altering histone deacetylase expression.

Aung HT, Schroder K, Himes SR, Brion K, van Zuylen W, Trieu A, Suzuki H, Hayashizaki Y, Hume DA, Sweet MJ, Ravasi T.

FASEB J. 2006 Jul;20(9):1315-27.


Differential regulation of HIF-1alpha isoforms in murine macrophages by TLR4 and adenosine A(2A) receptor agonists.

Ramanathan M, Luo W, Csóka B, Haskó G, Lukashev D, Sitkovsky MV, Leibovich SJ.

J Leukoc Biol. 2009 Sep;86(3):681-9. doi: 10.1189/jlb.0109021. Epub 2009 May 28.


Hypoxic stress up-regulates the expression of Toll-like receptor 4 in macrophages via hypoxia-inducible factor.

Kim SY, Choi YJ, Joung SM, Lee BH, Jung YS, Lee JY.

Immunology. 2010 Apr;129(4):516-24. doi: 10.1111/j.1365-2567.2009.03203.x. Epub 2009 Dec 2.


Zinc finger protein 64 promotes Toll-like receptor-triggered proinflammatory and type I interferon production in macrophages by enhancing p65 subunit activation.

Wang C, Liu X, Liu Y, Zhang Q, Yao Z, Huang B, Zhang P, Li N, Cao X.

J Biol Chem. 2013 Aug 23;288(34):24600-8. doi: 10.1074/jbc.M113.473397. Epub 2013 Jul 15.


Melatonin modulates TLR4-mediated inflammatory genes through MyD88- and TRIF-dependent signaling pathways in lipopolysaccharide-stimulated RAW264.7 cells.

Xia MZ, Liang YL, Wang H, Chen X, Huang YY, Zhang ZH, Chen YH, Zhang C, Zhao M, Xu DX, Song LH.

J Pineal Res. 2012 Nov;53(4):325-34. doi: 10.1111/j.1600-079X.2012.01002.x. Epub 2012 Apr 27.


LPS induces hypoxia-inducible factor 1 activation in macrophage-differentiated cells in a reactive oxygen species-dependent manner.

Nishi K, Oda T, Takabuchi S, Oda S, Fukuda K, Adachi T, Semenza GL, Shingu K, Hirota K.

Antioxid Redox Signal. 2008 May;10(5):983-95. doi: 10.1089/ars.2007.1825.


The involvement of sphingosine kinase 1 in LPS-induced Toll-like receptor 4-mediated accumulation of HIF-1α protein, activation of ASK1 and production of the pro-inflammatory cytokine IL-6.

Pchejetski D, Nunes J, Coughlan K, Lall H, Pitson SM, Waxman J, Sumbayev VV.

Immunol Cell Biol. 2011 Feb;89(2):268-74. doi: 10.1038/icb.2010.91. Epub 2010 Jul 27.


Cutting edge: Essential role of hypoxia inducible factor-1alpha in development of lipopolysaccharide-induced sepsis.

Peyssonnaux C, Cejudo-Martin P, Doedens A, Zinkernagel AS, Johnson RS, Nizet V.

J Immunol. 2007 Jun 15;178(12):7516-9.


Phosphorylation of histone deacetylase 7 by protein kinase D mediates T cell receptor-induced Nur77 expression and apoptosis.

Dequiedt F, Van Lint J, Lecomte E, Van Duppen V, Seufferlein T, Vandenheede JR, Wattiez R, Kettmann R.

J Exp Med. 2005 Mar 7;201(5):793-804. Epub 2005 Feb 28.


A dynamic role for HDAC7 in MEF2-mediated muscle differentiation.

Dressel U, Bailey PJ, Wang SC, Downes M, Evans RM, Muscat GE.

J Biol Chem. 2001 May 18;276(20):17007-13. Epub 2001 Mar 8.


Hypoxia and hypoxia-inducible factor-1α provoke toll-like receptor signalling-induced inflammation in rheumatoid arthritis.

Hu F, Mu R, Zhu J, Shi L, Li Y, Liu X, Shao W, Li G, Li M, Su Y, Cohen PL, Qiu X, Li Z.

Ann Rheum Dis. 2014 May;73(5):928-36. doi: 10.1136/annrheumdis-2012-202444. Epub 2013 May 3.


Peroxiredoxin 1 stimulates endothelial cell expression of VEGF via TLR4 dependent activation of HIF-1α.

Riddell JR, Maier P, Sass SN, Moser MT, Foster BA, Gollnick SO.

PLoS One. 2012;7(11):e50394. doi: 10.1371/journal.pone.0050394. Epub 2012 Nov 21.


Dysregulated expression of miR-146a contributes to age-related dysfunction of macrophages.

Jiang M, Xiang Y, Wang D, Gao J, Liu D, Liu Y, Liu S, Zheng D.

Aging Cell. 2012 Feb;11(1):29-40. doi: 10.1111/j.1474-9726.2011.00757.x. Epub 2011 Nov 16.


Pyruvate kinase M2 regulates Hif-1α activity and IL-1β induction and is a critical determinant of the warburg effect in LPS-activated macrophages.

Palsson-McDermott EM, Curtis AM, Goel G, Lauterbach MA, Sheedy FJ, Gleeson LE, van den Bosch MW, Quinn SR, Domingo-Fernandez R, Johnston DG, Jiang JK, Israelsen WJ, Keane J, Thomas C, Clish C, Vander Heiden M, Xavier RJ, O'Neill LA.

Cell Metab. 2015 Jan 6;21(1):65-80. doi: 10.1016/j.cmet.2014.12.005. Erratum in: Cell Metab. 2015 Feb 3;21(2):347. Jiang, Jain-Kang [corrected to Jiang, Jian-Kang]; Vanden Heiden, Matthew [corrected to Vander Heiden, Matthew].

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