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Items: 1 to 20 of 72

1.

Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3⁺ regulatory T cells.

Pierson W, Cauwe B, Policheni A, Schlenner SM, Franckaert D, Berges J, Humblet-Baron S, Schönefeldt S, Herold MJ, Hildeman D, Strasser A, Bouillet P, Lu LF, Matthys P, Freitas AA, Luther RJ, Weaver CT, Dooley J, Gray DH, Liston A.

Nat Immunol. 2013 Sep;14(9):959-65. doi: 10.1038/ni.2649. Epub 2013 Jul 14.

2.

Defective cell death signalling along the Bcl-2 regulated apoptosis pathway compromises Treg cell development and limits their functionality in mice.

Tischner D, Gaggl I, Peschel I, Kaufmann M, Tuzlak S, Drach M, Thuille N, Villunger A, Jan Wiegers G.

J Autoimmun. 2012 Feb;38(1):59-69. doi: 10.1016/j.jaut.2011.12.008. Epub 2012 Jan 17.

3.

Bach2 regulates homeostasis of Foxp3+ regulatory T cells and protects against fatal lung disease in mice.

Kim EH, Gasper DJ, Lee SH, Plisch EH, Svaren J, Suresh M.

J Immunol. 2014 Feb 1;192(3):985-95. doi: 10.4049/jimmunol.1302378. Epub 2013 Dec 23.

4.

Preferential control of induced regulatory T cell homeostasis via a Bim/Bcl-2 axis.

Wang X, Szymczak-Workman AL, Gravano DM, Workman CJ, Green DR, Vignali DA.

Cell Death Dis. 2012 Feb 9;3:e270. doi: 10.1038/cddis.2012.9.

5.

Differential requirement of PKC-theta in the development and function of natural regulatory T cells.

Gupta S, Manicassamy S, Vasu C, Kumar A, Shang W, Sun Z.

Mol Immunol. 2008 Dec;46(2):213-24. doi: 10.1016/j.molimm.2008.08.275. Epub 2008 Oct 8.

6.

Foxp3 transcription factor is proapoptotic and lethal to developing regulatory T cells unless counterbalanced by cytokine survival signals.

Tai X, Erman B, Alag A, Mu J, Kimura M, Katz G, Guinter T, McCaughtry T, Etzensperger R, Feigenbaum L, Singer DS, Singer A.

Immunity. 2013 Jun 27;38(6):1116-28. doi: 10.1016/j.immuni.2013.02.022. Epub 2013 Jun 6.

7.

The control of CD4+CD25+Foxp3+ regulatory T cell survival.

Pandiyan P, Lenardo MJ.

Biol Direct. 2008 Feb 27;3:6. doi: 10.1186/1745-6150-3-6.

8.

A major role for Bim in regulatory T cell homeostasis.

Chougnet CA, Tripathi P, Lages CS, Raynor J, Sholl A, Fink P, Plas DR, Hildeman DA.

J Immunol. 2011 Jan 1;186(1):156-63. doi: 10.4049/jimmunol.1001505. Epub 2010 Nov 22.

9.

Apoptosis signaling is altered in CD4⁺CD25⁺FoxP3⁺ T regulatory lymphocytes in pre-eclampsia.

Darmochwal-Kolarz D, Saito S, Tabarkiewicz J, Kolarz B, Rolinski J, Leszczynska-Gorzelak B, Oleszczuk J.

Int J Mol Sci. 2012;13(6):6548-60. doi: 10.3390/ijms13066548. Epub 2012 May 29.

10.

IL-2 promotes the function of memory-like autoregulatory CD8+ T cells but suppresses their development via FoxP3+ Treg cells.

Shameli A, Yamanouchi J, Tsai S, Yang Y, Clemente-Casares X, Moore A, Serra P, Santamaria P.

Eur J Immunol. 2013 Feb;43(2):394-403. doi: 10.1002/eji.201242845. Epub 2013 Jan 15.

11.

Stability and function of regulatory T cells is maintained by a neuropilin-1-semaphorin-4a axis.

Delgoffe GM, Woo SR, Turnis ME, Gravano DM, Guy C, Overacre AE, Bettini ML, Vogel P, Finkelstein D, Bonnevier J, Workman CJ, Vignali DA.

Nature. 2013 Sep 12;501(7466):252-6. doi: 10.1038/nature12428. Epub 2013 Aug 4.

12.

Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+ regulatory T cell development via the CD27-CD70 pathway.

Coquet JM, Ribot JC, Bąbała N, Middendorp S, van der Horst G, Xiao Y, Neves JF, Fonseca-Pereira D, Jacobs H, Pennington DJ, Silva-Santos B, Borst J.

J Exp Med. 2013 Apr 8;210(4):715-28. doi: 10.1084/jem.20112061. Epub 2013 Apr 1.

13.

IL-2 contributes to maintaining a balance between CD4+Foxp3+ regulatory T cells and effector CD4+ T cells required for immune control of blood-stage malaria infection.

Berretta F, St-Pierre J, Piccirillo CA, Stevenson MM.

J Immunol. 2011 Apr 15;186(8):4862-71. doi: 10.4049/jimmunol.1003777. Epub 2011 Mar 9.

14.

Engagement of TLR2 does not reverse the suppressor function of mouse regulatory T cells, but promotes their survival.

Chen Q, Davidson TS, Huter EN, Shevach EM.

J Immunol. 2009 Oct 1;183(7):4458-66. doi: 10.4049/jimmunol.0901465. Epub 2009 Sep 11.

15.

Natural killer cells prevent CD28-mediated Foxp3 transcription in CD4+CD25- T lymphocytes.

Brillard E, Pallandre JR, Chalmers D, Ryffel B, Radlovic A, Seilles E, Rohrlich PS, Pivot X, Tiberghien P, Saas P, Borg C.

Exp Hematol. 2007 Mar;35(3):416-25.

PMID:
17309822
16.

Two lysines in the forkhead domain of foxp3 are key to T regulatory cell function.

Liu Y, Wang L, Han R, Beier UH, Hancock WW.

PLoS One. 2012;7(1):e29035. doi: 10.1371/journal.pone.0029035. Epub 2012 Jan 11.

17.

Bcl-xL is required for the development of functional regulatory CD4 cells in lupus-afflicted mice following treatment with a tolerogenic peptide.

Sharabi A, Lapter S, Mozes E.

J Autoimmun. 2010 Mar;34(2):87-95. doi: 10.1016/j.jaut.2009.06.002. Epub 2009 Jul 12.

PMID:
19596183
18.

Dendritic cells support homeostatic expansion of Foxp3+ regulatory T cells in Foxp3.LuciDTR mice.

Suffner J, Hochweller K, Kühnle MC, Li X, Kroczek RA, Garbi N, Hämmerling GJ.

J Immunol. 2010 Feb 15;184(4):1810-20. doi: 10.4049/jimmunol.0902420. Epub 2010 Jan 18.

19.

Functional dynamics of Foxp3⁺ regulatory T cells in mice and humans.

Bin Dhuban K, Kornete M, S Mason E, Piccirillo CA.

Immunol Rev. 2014 May;259(1):140-58. doi: 10.1111/imr.12168. Review.

PMID:
24712464
20.

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