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Items: 1 to 20 of 149

1.

The neuroinflammation marker translocator protein is not elevated in individuals with mild-to-moderate depression: a [¹¹C]PBR28 PET study.

Hannestad J, DellaGioia N, Gallezot JD, Lim K, Nabulsi N, Esterlis I, Pittman B, Lee JY, O'Connor KC, Pelletier D, Carson RE.

Brain Behav Immun. 2013 Oct;33:131-8. doi: 10.1016/j.bbi.2013.06.010. Epub 2013 Jul 9.

2.

Cocaine abuse in humans is not associated with increased microglial activation: an 18-kDa translocator protein positron emission tomography imaging study with [11C]PBR28.

Narendran R, Lopresti BJ, Mason NS, Deuitch L, Paris J, Himes ML, Kodavali CV, Nimgaonkar VL.

J Neurosci. 2014 Jul 23;34(30):9945-50. doi: 10.1523/JNEUROSCI.0928-14.2014.

3.

Endotoxin-induced systemic inflammation activates microglia: [¹¹C]PBR28 positron emission tomography in nonhuman primates.

Hannestad J, Gallezot JD, Schafbauer T, Lim K, Kloczynski T, Morris ED, Carson RE, Ding YS, Cosgrove KP.

Neuroimage. 2012 Oct 15;63(1):232-9. doi: 10.1016/j.neuroimage.2012.06.055. Epub 2012 Jul 6.

4.

In vivo evidence of a functional association between immune cells in blood and brain in healthy human subjects.

Kanegawa N, Collste K, Forsberg A, Schain M, Arakawa R, Jucaite A, Lekander M, Olgart Höglund C, Kosek E, Lampa J, Halldin C, Farde L, Varrone A, Cervenka S.

Brain Behav Immun. 2016 May;54:149-157. doi: 10.1016/j.bbi.2016.01.019. Epub 2016 Jan 25.

PMID:
26820224
5.

Neuroinflammation in Temporal Lobe Epilepsy Measured Using Positron Emission Tomographic Imaging of Translocator Protein.

Gershen LD, Zanotti-Fregonara P, Dustin IH, Liow JS, Hirvonen J, Kreisl WC, Jenko KJ, Inati SK, Fujita M, Morse CL, Brouwer C, Hong JS, Pike VW, Zoghbi SS, Innis RB, Theodore WH.

JAMA Neurol. 2015 Aug;72(8):882-8. doi: 10.1001/jamaneurol.2015.0941. Erratum in: JAMA Neurol. 2015 Aug;72(8):950.

6.

Cerebellum Can Serve As a Pseudo-Reference Region in Alzheimer Disease to Detect Neuroinflammation Measured with PET Radioligand Binding to Translocator Protein.

Lyoo CH, Ikawa M, Liow JS, Zoghbi SS, Morse CL, Pike VW, Fujita M, Innis RB, Kreisl WC.

J Nucl Med. 2015 May;56(5):701-6. doi: 10.2967/jnumed.114.146027. Epub 2015 Mar 12.

7.

Role of translocator protein density, a marker of neuroinflammation, in the brain during major depressive episodes.

Setiawan E, Wilson AA, Mizrahi R, Rusjan PM, Miler L, Rajkowska G, Suridjan I, Kennedy JL, Rekkas PV, Houle S, Meyer JH.

JAMA Psychiatry. 2015 Mar;72(3):268-75. doi: 10.1001/jamapsychiatry.2014.2427.

8.

A genetic polymorphism for translocator protein 18 kDa affects both in vitro and in vivo radioligand binding in human brain to this putative biomarker of neuroinflammation.

Kreisl WC, Jenko KJ, Hines CS, Lyoo CH, Corona W, Morse CL, Zoghbi SS, Hyde T, Kleinman JE, Pike VW, McMahon FJ, Innis RB; Biomarkers Consortium PET Radioligand Project Team.

J Cereb Blood Flow Metab. 2013 Jan;33(1):53-8. doi: 10.1038/jcbfm.2012.131. Epub 2012 Sep 12.

9.

Comparison of standardized uptake values with volume of distribution for quantitation of [(11)C]PBR28 brain uptake.

Yoder KK, Territo PR, Hutchins GD, Hannestad J, Morris ED, Gallezot JD, Normandin MD, Cosgrove KP.

Nucl Med Biol. 2015 Mar;42(3):305-8. doi: 10.1016/j.nucmedbio.2014.11.003. Epub 2014 Nov 15.

10.

Imaging robust microglial activation after lipopolysaccharide administration in humans with PET.

Sandiego CM, Gallezot JD, Pittman B, Nabulsi N, Lim K, Lin SF, Matuskey D, Lee JY, O'Connor KC, Huang Y, Carson RE, Hannestad J, Cosgrove KP.

Proc Natl Acad Sci U S A. 2015 Oct 6;112(40):12468-73. doi: 10.1073/pnas.1511003112. Epub 2015 Sep 18.

11.

Quantitative imaging of neuroinflammation in human white matter: a positron emission tomography study with translocator protein 18 kDa radioligand, [18F]-FEPPA.

Suridjan I, Rusjan PM, Kenk M, Verhoeff NP, Voineskos AN, Rotenberg D, Wilson AA, Meyer JH, Houle S, Mizrahi R.

Synapse. 2014 Nov;68(11):536-47. doi: 10.1002/syn.21765. Epub 2014 Jul 28.

PMID:
25043159
12.

In vivo imaging of microglial activation by positron emission tomography with [(11)C]PBR28 in the 5XFAD model of Alzheimer's disease.

Mirzaei N, Tang SP, Ashworth S, Coello C, Plisson C, Passchier J, Selvaraj V, Tyacke RJ, Nutt DJ, Sastre M.

Glia. 2016 Jun;64(6):993-1006. doi: 10.1002/glia.22978. Epub 2016 Mar 9.

PMID:
26959396
13.

Imaging neuroinflammation in gray and white matter in schizophrenia: an in-vivo PET study with [18F]-FEPPA.

Kenk M, Selvanathan T, Rao N, Suridjan I, Rusjan P, Remington G, Meyer JH, Wilson AA, Houle S, Mizrahi R.

Schizophr Bull. 2015 Jan;41(1):85-93. doi: 10.1093/schbul/sbu157. Epub 2014 Nov 9.

14.

Comparison of [(11)C]-(R)-PK 11195 and [(11)C]PBR28, two radioligands for translocator protein (18 kDa) in human and monkey: Implications for positron emission tomographic imaging of this inflammation biomarker.

Kreisl WC, Fujita M, Fujimura Y, Kimura N, Jenko KJ, Kannan P, Hong J, Morse CL, Zoghbi SS, Gladding RL, Jacobson S, Oh U, Pike VW, Innis RB.

Neuroimage. 2010 Feb 15;49(4):2924-32. doi: 10.1016/j.neuroimage.2009.11.056. Epub 2009 Dec 4.

15.

Neuroinflammation in healthy aging: a PET study using a novel Translocator Protein 18kDa (TSPO) radioligand, [(18)F]-FEPPA.

Suridjan I, Rusjan PM, Voineskos AN, Selvanathan T, Setiawan E, Strafella AP, Wilson AA, Meyer JH, Houle S, Mizrahi R.

Neuroimage. 2014 Jan 1;84:868-75. doi: 10.1016/j.neuroimage.2013.09.021. Epub 2013 Sep 21.

PMID:
24064066
16.

Kinetic analysis of the translocator protein positron emission tomography ligand [18F]GE-180 in the human brain.

Feeney C, Scott G, Raffel J, Roberts S, Coello C, Jolly A, Searle G, Goldstone AP, Brooks DJ, Nicholas RS, Trigg W, Gunn RN, Sharp DJ.

Eur J Nucl Med Mol Imaging. 2016 Nov;43(12):2201-2210. Epub 2016 Jun 28.

17.

Neuroinflammatory component of gray matter pathology in multiple sclerosis.

Herranz E, Giannì C, Louapre C, Treaba CA, Govindarajan ST, Ouellette R, Loggia ML, Sloane JA, Madigan N, Izquierdo-Garcia D, Ward N, Mangeat G, Granberg T, Klawiter EC, Catana C, Hooker JM, Taylor N, Ionete C, Kinkel RP, Mainero C.

Ann Neurol. 2016 Nov;80(5):776-790. doi: 10.1002/ana.24791. Epub 2016 Oct 25.

PMID:
27686563
18.

Positron Emission Tomography studies with [11C]PBR28 in the Healthy Rodent Brain: Validating SUV as an Outcome Measure of Neuroinflammation.

Tóth M, Doorduin J, Häggkvist J, Varrone A, Amini N, Halldin C, Gulyás B.

PLoS One. 2015 May 21;10(5):e0125917. doi: 10.1371/journal.pone.0125917. eCollection 2015.

19.

Influence of TSPO genotype on 11C-PBR28 standardized uptake values.

Yoder KK, Nho K, Risacher SL, Kim S, Shen L, Saykin AJ.

J Nucl Med. 2013 Aug;54(8):1320-2. doi: 10.2967/jnumed.112.118885. Epub 2013 Jun 19.

20.

Regional brain distribution of translocator protein using [(11)C]DPA-713 PET in individuals infected with HIV.

Coughlin JM, Wang Y, Ma S, Yue C, Kim PK, Adams AV, Roosa HV, Gage KL, Stathis M, Rais R, Rojas C, McGlothan JL, Watkins CC, Sacktor N, Guilarte TR, Zhou Y, Sawa A, Slusher BS, Caffo B, Kassiou M, Endres CJ, Pomper MG.

J Neurovirol. 2014 Jun;20(3):219-32. doi: 10.1007/s13365-014-0239-5. Epub 2014 Feb 25.

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