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Items: 1 to 20 of 211

1.

Neuroprotective effect of bicyclol in rat ischemic stroke: down-regulates TLR4, TLR9, TRAF6, NF-κB, MMP-9 and up-regulates claudin-5 expression.

Zhang J, Fu B, Zhang X, Chen L, Zhang L, Zhao X, Bai X, Zhu C, Cui L, Wang L.

Brain Res. 2013 Aug 28;1528:80-8. doi: 10.1016/j.brainres.2013.06.032. Epub 2013 Jul 10.

PMID:
23850770
2.

Luteolin downregulates TLR4, TLR5, NF-κB and p-p38MAPK expression, upregulates the p-ERK expression, and protects rat brains against focal ischemia.

Qiao H, Zhang X, Zhu C, Dong L, Wang L, Zhang X, Xing Y, Wang C, Ji Y, Cao X.

Brain Res. 2012 Apr 11;1448:71-81. doi: 10.1016/j.brainres.2012.02.003. Epub 2012 Feb 9.

PMID:
22377454
3.

Bicyclol upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia.

Zhang J, Fu B, Zhang X, Zhang L, Bai X, Zhao X, Chen L, Cui L, Zhu C, Wang L, Zhao Y, Zhao T, Wang X.

Brain Res Bull. 2014 Jan;100:38-43. doi: 10.1016/j.brainresbull.2013.11.001. Epub 2013 Nov 16.

PMID:
24252362
4.

Protective effect of shikonin in experimental ischemic stroke: attenuated TLR4, p-p38MAPK, NF-κB, TNF-α and MMP-9 expression, up-regulated claudin-5 expression, ameliorated BBB permeability.

Wang L, Li Z, Zhang X, Wang S, Zhu C, Miao J, Chen L, Cui L, Qiao H.

Neurochem Res. 2014 Jan;39(1):97-106. doi: 10.1007/s11064-013-1194-x. Epub 2013 Nov 19.

PMID:
24248858
5.

Protective effect of naringenin in experimental ischemic stroke: down-regulated NOD2, RIP2, NF-κB, MMP-9 and up-regulated claudin-5 expression.

Bai X, Zhang X, Chen L, Zhang J, Zhang L, Zhao X, Zhao T, Zhao Y.

Neurochem Res. 2014 Aug;39(8):1405-15. doi: 10.1007/s11064-014-1326-y. Epub 2014 May 20.

PMID:
24842554
6.

Neuroprotective effect of early and short-time applying sophoridine in pMCAO rat brain: down-regulated TRAF6 and up-regulated p-ERK1/2 expression, ameliorated brain infaction and edema.

Liu Z, He D, Zhang X, Li Y, Zhu C, Dong L, Zhang X, Xing Y, Wang C, Qiao H, Chen L.

Brain Res Bull. 2012 Jul 1;88(4):379-84. doi: 10.1016/j.brainresbull.2012.04.003. Epub 2012 Apr 10.

PMID:
22521762
7.

Tanshinone II A down-regulates HMGB1, RAGE, TLR4, NF-kappaB expression, ameliorates BBB permeability and endothelial cell function, and protects rat brains against focal ischemia.

Wang L, Zhang X, Liu L, Cui L, Yang R, Li M, Du W.

Brain Res. 2010 Mar 19;1321:143-51. doi: 10.1016/j.brainres.2009.12.046. Epub 2010 Jan 4.

PMID:
20043889
8.

Oxymatrine protects rat brains against permanent focal ischemia and downregulates NF-kappaB expression.

Liu Y, Zhang XJ, Yang CH, Fan HG.

Brain Res. 2009 May 1;1268:174-80. doi: 10.1016/j.brainres.2009.02.069. Epub 2009 Mar 10.

PMID:
19285049
9.
10.

Pretreatment by evodiamine is neuroprotective in cerebral ischemia: up-regulated pAkt, pGSK3β, down-regulated NF-κB expression, and ameliorated BBB permeability.

Zhao T, Zhang X, Zhao Y, Zhang L, Bai X, Zhang J, Zhao X, Chen L, Wang L, Cui L.

Neurochem Res. 2014 Aug;39(8):1612-20. doi: 10.1007/s11064-014-1356-5. Epub 2014 Jun 12.

PMID:
24919817
11.

Neuroprotective effects of pioglitazone in a rat model of permanent focal cerebral ischemia are associated with peroxisome proliferator-activated receptor gamma-mediated suppression of nuclear factor-κB signaling pathway.

Zhang HL, Xu M, Wei C, Qin AP, Liu CF, Hong LZ, Zhao XY, Liu J, Qin ZH.

Neuroscience. 2011 Mar 10;176:381-95. doi: 10.1016/j.neuroscience.2010.12.029. Epub 2010 Dec 24.

PMID:
21185913
12.

Parthenolide is neuroprotective in rat experimental stroke model: downregulating NF-κB, phospho-p38MAPK, and caspase-1 and ameliorating BBB permeability.

Dong L, Qiao H, Zhang X, Zhang X, Wang C, Wang L, Cui L, Zhao J, Xing Y, Li Y, Liu Z, Zhu C.

Mediators Inflamm. 2013;2013:370804. doi: 10.1155/2013/370804. Epub 2013 Jul 11.

13.

Ulinastatin downregulates TLR4 and NF-kB expression and protects mouse brains against ischemia/reperfusion injury.

Li X, Su L, Zhang X, Zhang C, Wang L, Li Y, Zhang Y, He T, Zhu X, Cui L.

Neurol Res. 2017 Apr;39(4):367-373. doi: 10.1080/01616412.2017.1286541. Epub 2017 Feb 13.

PMID:
28191863
14.

Nobiletin protects against cerebral ischemia via activating the p-Akt, p-CREB, BDNF and Bcl-2 pathway and ameliorating BBB permeability in rat.

Zhang L, Zhao H, Zhang X, Chen L, Zhao X, Bai X, Zhang J.

Brain Res Bull. 2013 Jul;96:45-53. doi: 10.1016/j.brainresbull.2013.04.009. Epub 2013 May 2.

PMID:
23644141
15.

Nobiletin promotes antioxidant and anti-inflammatory responses and elicits protection against ischemic stroke in vivo.

Zhang L, Zhang X, Zhang C, Bai X, Zhang J, Zhao X, Chen L, Wang L, Zhu C, Cui L, Chen R, Zhao T, Zhao Y.

Brain Res. 2016 Apr 1;1636:130-41. doi: 10.1016/j.brainres.2016.02.013. Epub 2016 Feb 10.

PMID:
26874072
16.

Protection by silibinin against experimental ischemic stroke: up-regulated pAkt, pmTOR, HIF-1α and Bcl-2, down-regulated Bax, NF-κB expression.

Wang C, Wang Z, Zhang X, Zhang X, Dong L, Xing Y, Li Y, Liu Z, Chen L, Qiao H, Wang L, Zhu C.

Neurosci Lett. 2012 Oct 31;529(1):45-50. doi: 10.1016/j.neulet.2012.08.078. Epub 2012 Sep 19.

PMID:
22999929
17.

Neuroprotection of early and short-time applying berberine in the acute phase of cerebral ischemia: up-regulated pAkt, pGSK and pCREB, down-regulated NF-κB expression, ameliorated BBB permeability.

Zhang X, Zhang X, Wang C, Li Y, Dong L, Cui L, Wang L, Liu Z, Qiao H, Zhu C, Xing Y, Cao X, Ji Y, Zhao K.

Brain Res. 2012 Jun 12;1459:61-70. doi: 10.1016/j.brainres.2012.03.065. Epub 2012 Apr 4.

PMID:
22560097
18.

Paeonol pretreatment attenuates cerebral ischemic injury via upregulating expression of pAkt, Nrf2, HO-1 and ameliorating BBB permeability in mice.

Zhao Y, Fu B, Zhang X, Zhao T, Chen L, Zhang J, Wang X.

Brain Res Bull. 2014 Oct;109:61-7. doi: 10.1016/j.brainresbull.2014.09.008. Epub 2014 Oct 5.

PMID:
25286445
19.

The protection by octreotide against experimental ischemic stroke: up-regulated transcription factor Nrf2, HO-1 and down-regulated NF-κB expression.

Chen L, Wang L, Zhang X, Cui L, Xing Y, Dong L, Liu Z, Li Y, Zhang X, Wang C, Bai X, Zhang J, Zhang L, Zhao X.

Brain Res. 2012 Sep 26;1475:80-7. doi: 10.1016/j.brainres.2012.07.052. Epub 2012 Aug 1.

PMID:
22885292
20.

Curcumin inhibits TLR2/4-NF-κB signaling pathway and attenuates brain damage in permanent focal cerebral ischemia in rats.

Tu XK, Yang WZ, Chen JP, Chen Y, Ouyang LQ, Xu YC, Shi SS.

Inflammation. 2014 Oct;37(5):1544-51. doi: 10.1007/s10753-014-9881-6.

PMID:
24723245

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