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Items: 1 to 20 of 97

1.

Control of the hippo pathway by Set7-dependent methylation of Yap.

Oudhoff MJ, Freeman SA, Couzens AL, Antignano F, Kuznetsova E, Min PH, Northrop JP, Lehnertz B, Barsyte-Lovejoy D, Vedadi M, Arrowsmith CH, Nishina H, Gold MR, Rossi FM, Gingras AC, Zaph C.

Dev Cell. 2013 Jul 29;26(2):188-94. doi: 10.1016/j.devcel.2013.05.025. Epub 2013 Jul 11.

2.

SETD7 Controls Intestinal Regeneration and Tumorigenesis by Regulating Wnt/β-Catenin and Hippo/YAP Signaling.

Oudhoff MJ, Braam MJS, Freeman SA, Wong D, Rattray DG, Wang J, Antignano F, Snyder K, Refaeli I, Hughes MR, McNagny KM, Gold MR, Arrowsmith CH, Sato T, Rossi FMV, Tatlock JH, Owen DR, Brown PJ, Zaph C.

Dev Cell. 2016 Apr 4;37(1):47-57. doi: 10.1016/j.devcel.2016.03.002.

3.

Targeting YAP and Hippo signaling pathway in liver cancer.

Liu AM, Xu MZ, Chen J, Poon RT, Luk JM.

Expert Opin Ther Targets. 2010 Aug;14(8):855-68. doi: 10.1517/14728222.2010.499361. Review.

PMID:
20545481
4.

The Hippo pathway is controlled by Angiotensin II signaling and its reactivation induces apoptosis in podocytes.

Wennmann DO, Vollenbröker B, Eckart AK, Bonse J, Erdmann F, Wolters DA, Schenk LK, Schulze U, Kremerskothen J, Weide T, Pavenstädt H.

Cell Death Dis. 2014 Nov 13;5:e1519. doi: 10.1038/cddis.2014.476.

5.

Mask proteins are cofactors of Yorkie/YAP in the Hippo pathway.

Sidor CM, Brain R, Thompson BJ.

Curr Biol. 2013 Feb 4;23(3):223-8. doi: 10.1016/j.cub.2012.11.061. Epub 2013 Jan 17.

6.

Hippo pathway regulation by cell morphology and stress fibers.

Wada K, Itoga K, Okano T, Yonemura S, Sasaki H.

Development. 2011 Sep;138(18):3907-14. doi: 10.1242/dev.070987. Epub 2011 Aug 10.

7.

LIM-domain protein AJUBA suppresses malignant mesothelioma cell proliferation via Hippo signaling cascade.

Tanaka I, Osada H, Fujii M, Fukatsu A, Hida T, Horio Y, Kondo Y, Sato A, Hasegawa Y, Tsujimura T, Sekido Y.

Oncogene. 2015 Jan 2;34(1):73-83. doi: 10.1038/onc.2013.528. Epub 2013 Dec 16.

PMID:
24336325
8.

Intestinal Epithelial Cell-Intrinsic Deletion of Setd7 Identifies Role for Developmental Pathways in Immunity to Helminth Infection.

Oudhoff MJ, Antignano F, Chenery AL, Burrows K, Redpath SA, Braam MJ, Perona-Wright G, Zaph C.

PLoS Pathog. 2016 Sep 6;12(9):e1005876. doi: 10.1371/journal.ppat.1005876. eCollection 2016 Sep.

9.

YAP and TAZ, Hippo signaling targets, act as a rheostat for nuclear SHP2 function.

Tsutsumi R, Masoudi M, Takahashi A, Fujii Y, Hayashi T, Kikuchi I, Satou Y, Taira M, Hatakeyama M.

Dev Cell. 2013 Sep 30;26(6):658-65. doi: 10.1016/j.devcel.2013.08.013. Epub 2013 Sep 12.

10.

Tumor suppressor LATS1 is a negative regulator of oncogene YAP.

Hao Y, Chun A, Cheung K, Rashidi B, Yang X.

J Biol Chem. 2008 Feb 29;283(9):5496-509. Epub 2007 Dec 24.

11.

cAMP/PKA signalling reinforces the LATS-YAP pathway to fully suppress YAP in response to actin cytoskeletal changes.

Kim M, Kim M, Lee S, Kuninaka S, Saya H, Lee H, Lee S, Lim DS.

EMBO J. 2013 May 29;32(11):1543-55. doi: 10.1038/emboj.2013.102. Epub 2013 May 3.

12.

Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP.

Chen Q, Zhang N, Xie R, Wang W, Cai J, Choi KS, David KK, Huang B, Yabuta N, Nojima H, Anders RA, Pan D.

Genes Dev. 2015 Jun 15;29(12):1285-97. doi: 10.1101/gad.264234.115.

13.

Hippo-YAP signaling pathway: A new paradigm for cancer therapy.

Ma Y, Yang Y, Wang F, Wei Q, Qin H.

Int J Cancer. 2015 Nov 15;137(10):2275-86. doi: 10.1002/ijc.29073. Epub 2014 Jul 22. Review.

14.

The alteration of Hippo/YAP signaling in the development of hypertrophic cardiomyopathy.

Wang P, Mao B, Luo W, Wei B, Jiang W, Liu D, Song L, Ji G, Yang Z, Lai YQ, Yuan Z.

Basic Res Cardiol. 2014;109(5):435. doi: 10.1007/s00395-014-0435-8. Epub 2014 Aug 29.

PMID:
25168380
15.

(R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells.

Barsyte-Lovejoy D, Li F, Oudhoff MJ, Tatlock JH, Dong A, Zeng H, Wu H, Freeman SA, Schapira M, Senisterra GA, Kuznetsova E, Marcellus R, Allali-Hassani A, Kennedy S, Lambert JP, Couzens AL, Aman A, Gingras AC, Al-Awar R, Fish PV, Gerstenberger BS, Roberts L, Benn CL, Grimley RL, Braam MJ, Rossi FM, Sudol M, Brown PJ, Bunnage ME, Owen DR, Zaph C, Vedadi M, Arrowsmith CH.

Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12853-8. doi: 10.1073/pnas.1407358111. Epub 2014 Aug 18.

16.

Both TEAD-binding and WW domains are required for the growth stimulation and oncogenic transformation activity of yes-associated protein.

Zhao B, Kim J, Ye X, Lai ZC, Guan KL.

Cancer Res. 2009 Feb 1;69(3):1089-98. doi: 10.1158/0008-5472.CAN-08-2997. Epub 2009 Jan 13.

17.

Normal hematopoietic stem cell function in mice with enforced expression of the Hippo signaling effector YAP1.

Jansson L, Larsson J.

PLoS One. 2012;7(2):e32013. doi: 10.1371/journal.pone.0032013. Epub 2012 Feb 21.

18.

Direct Exposure to Ethanol Disrupts Junctional Cell-Cell Contact and Hippo-YAP Signaling in HL-1 Murine Atrial Cardiomyocytes.

Noritake K, Aki T, Funakoshi T, Unuma K, Uemura K.

PLoS One. 2015 Aug 28;10(8):e0136952. doi: 10.1371/journal.pone.0136952. eCollection 2015.

19.

Energy stress regulates hippo-YAP signaling involving AMPK-mediated regulation of angiomotin-like 1 protein.

DeRan M, Yang J, Shen CH, Peters EC, Fitamant J, Chan P, Hsieh M, Zhu S, Asara JM, Zheng B, Bardeesy N, Liu J, Wu X.

Cell Rep. 2014 Oct 23;9(2):495-503. doi: 10.1016/j.celrep.2014.09.036. Epub 2014 Oct 16.

20.

The methyltransferase Set7/9 (Setd7) is dispensable for the p53-mediated DNA damage response in vivo.

Campaner S, Spreafico F, Burgold T, Doni M, Rosato U, Amati B, Testa G.

Mol Cell. 2011 Aug 19;43(4):681-8. doi: 10.1016/j.molcel.2011.08.007.

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