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Items: 1 to 20 of 159

1.

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes.

Gilbert LA, Larson MH, Morsut L, Liu Z, Brar GA, Torres SE, Stern-Ginossar N, Brandman O, Whitehead EH, Doudna JA, Lim WA, Weissman JS, Qi LS.

Cell. 2013 Jul 18;154(2):442-51. doi: 10.1016/j.cell.2013.06.044. Epub 2013 Jul 11.

2.

CRISPR RNA-guided activation of endogenous human genes.

Maeder ML, Linder SJ, Cascio VM, Fu Y, Ho QH, Joung JK.

Nat Methods. 2013 Oct;10(10):977-9. doi: 10.1038/nmeth.2598. Epub 2013 Jul 25.

3.

CRISPR Technology for Genome Activation and Repression in Mammalian Cells.

Du D, Qi LS.

Cold Spring Harb Protoc. 2016 Jan 4;2016(1):pdb.prot090175. doi: 10.1101/pdb.prot090175.

PMID:
26729910
4.

Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression.

Qi LS, Larson MH, Gilbert LA, Doudna JA, Weissman JS, Arkin AP, Lim WA.

Cell. 2013 Feb 28;152(5):1173-83. doi: 10.1016/j.cell.2013.02.022.

5.

Transcriptional reprogramming in yeast using dCas9 and combinatorial gRNA strategies.

Jensen ED, Ferreira R, Jakočiūnas T, Arsovska D, Zhang J, Ding L, Smith JD, David F, Nielsen J, Jensen MK, Keasling JD.

Microb Cell Fact. 2017 Mar 15;16(1):46. doi: 10.1186/s12934-017-0664-2.

6.

RNA-guided transcriptional regulation in planta via synthetic dCas9-based transcription factors.

Piatek A, Ali Z, Baazim H, Li L, Abulfaraj A, Al-Shareef S, Aouida M, Mahfouz MM.

Plant Biotechnol J. 2015 May;13(4):578-89. doi: 10.1111/pbi.12284. Epub 2014 Nov 14.

7.

Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds.

Zalatan JG, Lee ME, Almeida R, Gilbert LA, Whitehead EH, La Russa M, Tsai JC, Weissman JS, Dueber JE, Qi LS, Lim WA.

Cell. 2015 Jan 15;160(1-2):339-50. doi: 10.1016/j.cell.2014.11.052. Epub 2014 Dec 18.

8.

Transcriptional Regulation with CRISPR/Cas9 Effectors in Mammalian Cells.

Pham H, Kearns NA, Maehr R.

Methods Mol Biol. 2016;1358:43-57. doi: 10.1007/978-1-4939-3067-8_3.

PMID:
26463376
9.

An Introduction to CRISPR Technology for Genome Activation and Repression in Mammalian Cells.

Du D, Qi LS.

Cold Spring Harb Protoc. 2016 Jan 4;2016(1):pdb.top086835. doi: 10.1101/pdb.top086835.

PMID:
26729914
10.

CRISPRi is not strand-specific at all loci and redefines the transcriptional landscape.

Howe FS, Russell A, Lamstaes AR, El-Sagheer A, Nair A, Brown T, Mellor J.

Elife. 2017 Oct 23;6. pii: e29878. doi: 10.7554/eLife.29878.

11.

CRISPR interference (CRISPRi) for sequence-specific control of gene expression.

Larson MH, Gilbert LA, Wang X, Lim WA, Weissman JS, Qi LS.

Nat Protoc. 2013 Nov;8(11):2180-96. doi: 10.1038/nprot.2013.132. Epub 2013 Oct 17.

12.

Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system.

Cheng AW, Wang H, Yang H, Shi L, Katz Y, Theunissen TW, Rangarajan S, Shivalila CS, Dadon DB, Jaenisch R.

Cell Res. 2013 Oct;23(10):1163-71. doi: 10.1038/cr.2013.122. Epub 2013 Aug 27.

13.

Using an Inducible CRISPR-dCas9-KRAB Effector System to Dissect Transcriptional Regulation in Human Embryonic Stem Cells.

Parsi KM, Hennessy E, Kearns N, Maehr R.

Methods Mol Biol. 2017;1507:221-233.

PMID:
27832543
14.

Evaluation of sgRNA target sites for CRISPR-mediated repression of TP53.

Lawhorn IE, Ferreira JP, Wang CL.

PLoS One. 2014 Nov 14;9(11):e113232. doi: 10.1371/journal.pone.0113232. eCollection 2014.

15.

Construction of a Gene Knockdown System Based on Catalytically Inactive ("Dead") Cas9 (dCas9) in Staphylococcus aureus.

Zhao C, Shu X, Sun B.

Appl Environ Microbiol. 2017 May 31;83(12). pii: e00291-17. doi: 10.1128/AEM.00291-17. Print 2017 Jun 15.

16.

Sequence-specific inhibition of microRNA via CRISPR/CRISPRi system.

Zhao Y, Dai Z, Liang Y, Yin M, Ma K, He M, Ouyang H, Teng CB.

Sci Rep. 2014 Feb 3;4:3943. doi: 10.1038/srep03943.

17.

Optimizing sgRNA position markedly improves the efficiency of CRISPR/dCas9-mediated transcriptional repression.

Radzisheuskaya A, Shlyueva D, Müller I, Helin K.

Nucleic Acids Res. 2016 Oct 14;44(18):e141. Epub 2016 Jun 28.

18.

Gene silencing by CRISPR interference in mycobacteria.

Choudhary E, Thakur P, Pareek M, Agarwal N.

Nat Commun. 2015 Feb 25;6:6267. doi: 10.1038/ncomms7267.

PMID:
25711368
19.

Comparison of TALE designer transcription factors and the CRISPR/dCas9 in regulation of gene expression by targeting enhancers.

Gao X, Tsang JC, Gaba F, Wu D, Lu L, Liu P.

Nucleic Acids Res. 2014 Nov 10;42(20):e155. doi: 10.1093/nar/gku836. Epub 2014 Sep 15.

20.

Gene transcription repression in Clostridium beijerinckii using CRISPR-dCas9.

Wang Y, Zhang ZT, Seo SO, Lynn P, Lu T, Jin YS, Blaschek HP.

Biotechnol Bioeng. 2016 Dec;113(12):2739-2743. doi: 10.1002/bit.26020. Epub 2016 Jun 20.

PMID:
27240718

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