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Items: 1 to 20 of 85

1.

Apoptosis-related BCL2-family members: Key players in chemotherapy.

Kontos CK, Christodoulou MI, Scorilas A.

Anticancer Agents Med Chem. 2014 Mar;14(3):353-74. Review.

PMID:
23848200
2.

Nature promises new anticancer agents: Interplay with the apoptosis-related BCL2 gene family.

Christodoulou MI, Kontos CK, Halabalaki M, Skaltsounis AL, Scorilas A.

Anticancer Agents Med Chem. 2014 Mar;14(3):375-99. Review.

PMID:
23848203
4.

Molecular profile of the BCL2 family of the apoptosis related genes in breast cancer cells after treatment with cytotoxic/cytostatic drugs.

Thomadaki H, Scorilas A.

Connect Tissue Res. 2008;49(3):261-4. doi: 10.1080/03008200802147829. Review.

PMID:
18661356
5.

Drugs targeting Bcl-2 family members as an emerging strategy in cancer.

Leber B, Geng F, Kale J, Andrews DW.

Expert Rev Mol Med. 2010 Sep 8;12:e28. doi: 10.1017/S1462399410001572. Review.

PMID:
20822554
6.

Apoptosis and cancer chemotherapy.

Makin G, Dive C.

Trends Cell Biol. 2001 Nov;11(11):S22-6. Review.

PMID:
11684438
7.

Pharmacological inhibition of the Bcl-2 family of apoptosis regulators as cancer therapy.

Richardson A, Kaye SB.

Curr Mol Pharmacol. 2008 Nov;1(3):244-54. Review.

PMID:
20021437
8.

The BCL2 Family: Key Mediators of the Apoptotic Response to Targeted Anticancer Therapeutics.

Hata AN, Engelman JA, Faber AC.

Cancer Discov. 2015 May;5(5):475-87. doi: 10.1158/2159-8290.CD-15-0011. Epub 2015 Apr 20. Review.

9.

Resistance to chemotherapy via Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer cells.

Real PJ, Sierra A, De Juan A, Segovia JC, Lopez-Vega JM, Fernandez-Luna JL.

Oncogene. 2002 Oct 31;21(50):7611-8.

10.

ABT-737 induces expression of the death receptor 5 and sensitizes human cancer cells to TRAIL-induced apoptosis.

Song JH, Kandasamy K, Kraft AS.

J Biol Chem. 2008 Sep 5;283(36):25003-13. doi: 10.1074/jbc.M802511200. Epub 2008 Jul 3.

11.

Diagnosing and exploiting cancer's addiction to blocks in apoptosis.

Letai AG.

Nat Rev Cancer. 2008 Feb;8(2):121-32. doi: 10.1038/nrc2297. Review.

PMID:
18202696
12.

The BCL2-family of protein ligands as cancer drugs: the next generation of therapeutics.

Liu W, Bulgaru A, Haigentz M, Stein CA, Perez-Soler R, Mani S.

Curr Med Chem Anticancer Agents. 2003 May;3(3):217-23. Review.

PMID:
12769779
13.

Mcl-1 regulates survival and sensitivity to diverse apoptotic stimuli in human non-small cell lung cancer cells.

Song L, Coppola D, Livingston S, Cress D, Haura EB.

Cancer Biol Ther. 2005 Mar;4(3):267-76. Epub 2005 Mar 20.

PMID:
15753661
14.

Hypoxia-induced modulation of apoptosis and BCL-2 family proteins in different cancer cell types.

Sermeus A, Genin M, Maincent A, Fransolet M, Notte A, Leclere L, Riquier H, Arnould T, Michiels C.

PLoS One. 2012;7(11):e47519. doi: 10.1371/journal.pone.0047519. Epub 2012 Nov 5.

15.

Targeted BCL2 inhibition effectively inhibits neuroblastoma tumour growth.

Lamers F, Schild L, den Hartog IJ, Ebus ME, Westerhout EM, Ora I, Koster J, Versteeg R, Caron HN, Molenaar JJ.

Eur J Cancer. 2012 Nov;48(16):3093-103. doi: 10.1016/j.ejca.2012.01.037. Epub 2012 Feb 25.

16.

A functional role for nicotine in Bcl2 phosphorylation and suppression of apoptosis.

Mai H, May WS, Gao F, Jin Z, Deng X.

J Biol Chem. 2003 Jan 17;278(3):1886-91. Epub 2002 Nov 5.

17.

Role of Bcl-2 in tumour cell survival and implications for pharmacotherapy.

Tomek M, Akiyama T, Dass CR.

J Pharm Pharmacol. 2012 Dec;64(12):1695-702. doi: 10.1111/j.2042-7158.2012.01526.x. Epub 2012 Apr 25. Review.

PMID:
23146031
18.

MK-2206, an allosteric Akt inhibitor, enhances antitumor efficacy by standard chemotherapeutic agents or molecular targeted drugs in vitro and in vivo.

Hirai H, Sootome H, Nakatsuru Y, Miyama K, Taguchi S, Tsujioka K, Ueno Y, Hatch H, Majumder PK, Pan BS, Kotani H.

Mol Cancer Ther. 2010 Jul;9(7):1956-67. doi: 10.1158/1535-7163.MCT-09-1012. Epub 2010 Jun 22.

19.

FKBP38-Bcl-2 interaction: a novel link to chemoresistance.

Choi BH, Yoon HS.

Curr Opin Pharmacol. 2011 Aug;11(4):354-9. doi: 10.1016/j.coph.2011.04.013. Epub 2011 May 14. Review.

PMID:
21571591
20.

[The Bcl-2 family of proteins as drug targets].

Mazars A, Geneste O, Hickman J.

J Soc Biol. 2005;199(3):253-65. Review. French.

PMID:
16471266

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