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Items: 1 to 20 of 153

1.

Clinicopathological correlates of activating GNAS mutations in intraductal papillary mucinous neoplasm (IPMN) of the pancreas.

Dal Molin M, Matthaei H, Wu J, Blackford A, Debeljak M, Rezaee N, Wolfgang CL, Butturini G, Salvia R, Bassi C, Goggins MG, Kinzler KW, Vogelstein B, Eshleman JR, Hruban RH, Maitra A.

Ann Surg Oncol. 2013 Nov;20(12):3802-8. doi: 10.1245/s10434-013-3096-1.

2.

Intraductal papillary mucinous neoplasms of the pancreas with distinct pancreatic ductal adenocarcinomas are frequently of gastric subtype.

Ideno N, Ohtsuka T, Kono H, Fujiwara K, Oda Y, Aishima S, Ito T, Ishigami K, Tokunaga S, Ohuchida K, Takahata S, Nakamura M, Mizumoto K, Tanaka M.

Ann Surg. 2013 Jul;258(1):141-51. doi: 10.1097/SLA.0b013e31828cd008.

PMID:
23532108
3.

GNAS mutation is a frequent event in pancreatic intraductal papillary mucinous neoplasms and associated adenocarcinomas.

Hosoda W, Sasaki E, Murakami Y, Yamao K, Shimizu Y, Yatabe Y.

Virchows Arch. 2015 Jun;466(6):665-74. doi: 10.1007/s00428-015-1751-6.

PMID:
25796395
4.

GNAS and KRAS Mutations Define Separate Progression Pathways in Intraductal Papillary Mucinous Neoplasm-Associated Carcinoma.

Tan MC, Basturk O, Brannon AR, Bhanot U, Scott SN, Bouvier N, LaFemina J, Jarnagin WR, Berger MF, Klimstra D, Allen PJ.

J Am Coll Surg. 2015 May;220(5):845-54.e1. doi: 10.1016/j.jamcollsurg.2014.11.029.

5.

GNAS sequencing identifies IPMN-specific mutations in a subgroup of diminutive pancreatic cysts referred to as "incipient IPMNs".

Matthaei H, Wu J, Dal Molin M, Shi C, Perner S, Kristiansen G, Lingohr P, Kalff JC, Wolfgang CL, Kinzler KW, Vogelstein B, Maitra A, Hruban RH.

Am J Surg Pathol. 2014 Mar;38(3):360-3. doi: 10.1097/PAS.0000000000000117.

6.

Deep sequencing of cancer-related genes revealed GNAS mutations to be associated with intraductal papillary mucinous neoplasms and its main pancreatic duct dilation.

Takano S, Fukasawa M, Maekawa S, Kadokura M, Miura M, Shindo H, Takahashi E, Sato T, Enomoto N.

PLoS One. 2014 Jun 4;9(6):e98718. doi: 10.1371/journal.pone.0098718.

7.

Clinical significance of GNAS mutation in intraductal papillary mucinous neoplasm of the pancreas with concomitant pancreatic ductal adenocarcinoma.

Ideno N, Ohtsuka T, Matsunaga T, Kimura H, Watanabe Y, Tamura K, Aso T, Aishima S, Miyasaka Y, Ohuchida K, Ueda J, Takahata S, Oda Y, Mizumoto K, Tanaka M.

Pancreas. 2015 Mar;44(2):311-20. doi: 10.1097/MPA.0000000000000258.

PMID:
25479586
8.

Preoperative GNAS and KRAS testing in the diagnosis of pancreatic mucinous cysts.

Singhi AD, Nikiforova MN, Fasanella KE, McGrath KM, Pai RK, Ohori NP, Bartholow TL, Brand RE, Chennat JS, Lu X, Papachristou GI, Slivka A, Zeh HJ, Zureikat AH, Lee KK, Tsung A, Mantha GS, Khalid A.

Clin Cancer Res. 2014 Aug 15;20(16):4381-9. doi: 10.1158/1078-0432.CCR-14-0513.

9.

Assessment of clonality of multisegmental main duct intraductal papillary mucinous neoplasms of the pancreas based on GNAS mutation analysis.

Tamura K, Ohtsuka T, Matsunaga T, Kimura H, Watanabe Y, Ideno N, Aso T, Miyazaki T, Ohuchida K, Takahata S, Ito T, Ushijima Y, Oda Y, Mizumoto K, Tanaka M.

Surgery. 2015 Feb;157(2):277-84. doi: 10.1016/j.surg.2014.09.013.

PMID:
25530484
10.

Lessons from McCune-Albright syndrome-associated intraductal papillary mucinous neoplasms: : GNAS-activating mutations in pancreatic carcinogenesis.

Parvanescu A, Cros J, Ronot M, Hentic O, Grybek V, Couvelard A, Levy P, Chanson P, Ruszniewski P, Sauvanet A, Gaujoux S.

JAMA Surg. 2014 Aug;149(8):858-62. doi: 10.1001/jamasurg.2014.535.

PMID:
24898823
11.

The discrete nature and distinguishing molecular features of pancreatic intraductal tubulopapillary neoplasms and intraductal papillary mucinous neoplasms of the gastric type, pyloric gland variant.

Yamaguchi H, Kuboki Y, Hatori T, Yamamoto M, Shimizu K, Shiratori K, Shibata N, Shimizu M, Furukawa T.

J Pathol. 2013 Nov;231(3):335-41. doi: 10.1002/path.4242.

PMID:
23893889
12.

Targeted next-generation sequencing of cancer genes dissects the molecular profiles of intraductal papillary neoplasms of the pancreas.

Amato E, Molin MD, Mafficini A, Yu J, Malleo G, Rusev B, Fassan M, Antonello D, Sadakari Y, Castelli P, Zamboni G, Maitra A, Salvia R, Hruban RH, Bassi C, Capelli P, Lawlor RT, Goggins M, Scarpa A.

J Pathol. 2014 Jul;233(3):217-27. doi: 10.1002/path.4344.

13.

A GNAS mutation found in pancreatic intraductal papillary mucinous neoplasms induces drastic alterations of gene expression profiles with upregulation of mucin genes.

Komatsu H, Tanji E, Sakata N, Aoki T, Motoi F, Naitoh T, Katayose Y, Egawa S, Unno M, Furukawa T.

PLoS One. 2014 Feb 3;9(2):e87875. doi: 10.1371/journal.pone.0087875.

14.

Treatment strategy for main duct intraductal papillary mucinous neoplasms of the pancreas based on the assessment of recurrence in the remnant pancreas after resection: a retrospective review.

Tamura K, Ohtsuka T, Ideno N, Aso T, Shindo K, Aishima S, Ohuchida K, Takahata S, Ushijima Y, Ito T, Oda Y, Mizumoto K, Tanaka M.

Ann Surg. 2014 Feb;259(2):360-8. doi: 10.1097/SLA.0b013e3182a690ff.

PMID:
23989056
15.

Clinicopathological characteristics and molecular analyses of multifocal intraductal papillary mucinous neoplasms of the pancreas.

Matthaei H, Norris AL, Tsiatis AC, Olino K, Hong SM, dal Molin M, Goggins MG, Canto M, Horton KM, Jackson KD, Capelli P, Zamboni G, Bortesi L, Furukawa T, Egawa S, Ishida M, Ottomo S, Unno M, Motoi F, Wolfgang CL, Edil BH, Cameron JL, Eshleman JR, Schulick RD, Maitra A, Hruban RH.

Ann Surg. 2012 Feb;255(2):326-33. doi: 10.1097/SLA.0b013e3182378a18.

16.

Mutant GNAS detected in duodenal collections of secretin-stimulated pancreatic juice indicates the presence or emergence of pancreatic cysts.

Kanda M, Knight S, Topazian M, Syngal S, Farrell J, Lee J, Kamel I, Lennon AM, Borges M, Young A, Fujiwara S, Seike J, Eshleman J, Hruban RH, Canto MI, Goggins M.

Gut. 2013 Jul;62(7):1024-33. doi: 10.1136/gutjnl-2012-302823.

17.

Whole-exome sequencing uncovers frequent GNAS mutations in intraductal papillary mucinous neoplasms of the pancreas.

Furukawa T, Kuboki Y, Tanji E, Yoshida S, Hatori T, Yamamoto M, Shibata N, Shimizu K, Kamatani N, Shiratori K.

Sci Rep. 2011;1:161. doi: 10.1038/srep00161.

18.

Intraductal papillary mucinous neoplasms of the pancreas: an updated experience.

Sohn TA, Yeo CJ, Cameron JL, Hruban RH, Fukushima N, Campbell KA, Lillemoe KD.

Ann Surg. 2004 Jun;239(6):788-97; discussion 797-9.

19.

Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development.

Wu J, Matthaei H, Maitra A, Dal Molin M, Wood LD, Eshleman JR, Goggins M, Canto MI, Schulick RD, Edil BH, Wolfgang CL, Klein AP, Diaz LA Jr, Allen PJ, Schmidt CM, Kinzler KW, Papadopoulos N, Hruban RH, Vogelstein B.

Sci Transl Med. 2011 Jul 20;3(92):92ra66. doi: 10.1126/scitranslmed.3002543.

20.

Clinicopathological significance of somatic RNF43 mutation and aberrant expression of ring finger protein 43 in intraductal papillary mucinous neoplasms of the pancreas.

Sakamoto H, Kuboki Y, Hatori T, Yamamoto M, Sugiyama M, Shibata N, Shimizu K, Shiratori K, Furukawa T.

Mod Pathol. 2015 Feb;28(2):261-7. doi: 10.1038/modpathol.2014.98.

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