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Items: 1 to 20 of 74

1.

The role of thioredoxin 1 in the mycophenolic acid-induced apoptosis of insulin-producing cells.

Huh KH, Cho Y, Kim BS, Do JH, Park YJ, Joo DJ, Kim MS, Kim YS.

Cell Death Dis. 2013 Jul 11;4:e721. doi: 10.1038/cddis.2013.247.

2.

Illumina-microarray analysis of mycophenolic acid-induced cell death in an insulin-producing cell line and primary rat islet cells: new insights into apoptotic pathways involved.

Park YJ, Ahn HJ, Kim YS, Cho Y, Joo DJ, Ju MK.

Cell Signal. 2010 Nov;22(11):1773-82. doi: 10.1016/j.cellsig.2010.07.005.

PMID:
20637860
3.

Mycophenolic acid induces islet apoptosis by regulating mitogen-activated protein kinase activation.

Kim JY, Yoon SY, Park J, Kim YS.

Transplant Proc. 2006 Dec;38(10):3277-9.

PMID:
17175248
4.

The RhoGDI-alpha/JNK signaling pathway plays a significant role in mycophenolic acid-induced apoptosis in an insulin-secreting cell line.

Park YJ, Ahn HJ, Chang HK, Kim JY, Huh KH, Kim MS, Kim YS.

Cell Signal. 2009 Feb;21(2):356-64. doi: 10.1016/j.cellsig.2008.11.009.

PMID:
19041939
5.

Molecular mechanisms of cell death of mycophenolic acid-treated primary isolated rat islets: implication of mitogen-activated protein kinase activation.

Kim JY, Huh KH, Park YJ, Fang Y, Kang CM, Kim YS.

Transplant Proc. 2008 Oct;40(8):2575-7. doi: 10.1016/j.transproceed.2008.07.123.

PMID:
18929805
6.

Cadmium induces apoptosis in pancreatic β-cells through a mitochondria-dependent pathway: the role of oxidative stress-mediated c-Jun N-terminal kinase activation.

Chang KC, Hsu CC, Liu SH, Su CC, Yen CC, Lee MJ, Chen KL, Ho TJ, Hung DZ, Wu CC, Lu TH, Su YC, Chen YW, Huang CF.

PLoS One. 2013;8(2):e54374. doi: 10.1371/journal.pone.0054374.

7.

In vitro effects of mycophenolic acid on survival, function, and gene expression of pancreatic beta-cells.

Gallo R, Natale M, Vendrame F, Boggi U, Filipponi F, Marchetti P, Laghi Pasini F, Dotta F.

Acta Diabetol. 2012 Dec;49 Suppl 1:S123-31. doi: 10.1007/s00592-011-0368-8.

PMID:
22249339
8.

Cellular function of RhoGDI-α mediates the cycling of Rac1 and the regulation of pancreatic beta cell death.

Cho Y, Huh KH, Park YJ, Do JH, Joo DJ, Kim MS, Kim YS.

Transplant Proc. 2012 May;44(4):1083-5. doi: 10.1016/j.transproceed.2012.03.021.

PMID:
22564631
9.

PRMT3: new binding molecule to RhoGDI-α during mycophenolic acid-induced β-cell death.

Huh KH, Cho Y, Kim BS, Joo DJ, Kim MS, Kim YS.

Transplant Proc. 2014 May;46(4):1229-32. doi: 10.1016/j.transproceed.2013.12.016.

PMID:
24815167
10.

Prolonged depletion of guanosine triphosphate induces death of insulin-secreting cells by apoptosis.

Li G, Segu VB, Rabaglia ME, Luo RH, Kowluru A, Metz SA.

Endocrinology. 1998 Sep;139(9):3752-62.

PMID:
9724027
11.

Role of thioredoxin 1 and thioredoxin 2 on proliferation of human adipose tissue-derived mesenchymal stem cells.

Song JS, Cho HH, Lee BJ, Bae YC, Jung JS.

Stem Cells Dev. 2011 Sep;20(9):1529-37. doi: 10.1089/scd.2010.0364.

PMID:
21158569
12.

Phycocyanin protects INS-1E pancreatic beta cells against human islet amyloid polypeptide-induced apoptosis through attenuating oxidative stress and modulating JNK and p38 mitogen-activated protein kinase pathways.

Li XL, Xu G, Chen T, Wong YS, Zhao HL, Fan RR, Gu XM, Tong PC, Chan JC.

Int J Biochem Cell Biol. 2009 Jul;41(7):1526-35. doi: 10.1016/j.biocel.2009.01.002.

PMID:
19166964
13.

Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.

Ou YC, Yang CR, Cheng CL, Raung SL, Hung YY, Chen CJ.

Eur J Pharmacol. 2007 Jun 1;563(1-3):49-60.

PMID:
17341418
14.

The c-Jun amino-terminal kinase pathway is preferentially activated by interleukin-1 and controls apoptosis in differentiating pancreatic beta-cells.

Ammendrup A, Maillard A, Nielsen K, Aabenhus Andersen N, Serup P, Dragsbaek Madsen O, Mandrup-Poulsen T, Bonny C.

Diabetes. 2000 Sep;49(9):1468-76.

PMID:
10969830
15.

Nitric oxide contributes to cytokine-induced apoptosis in pancreatic beta cells via potentiation of JNK activity and inhibition of Akt.

Størling J, Binzer J, Andersson AK, Züllig RA, Tonnesen M, Lehmann R, Spinas GA, Sandler S, Billestrup N, Mandrup-Poulsen T.

Diabetologia. 2005 Oct;48(10):2039-50.

PMID:
16132952
16.

Involvement of mitochondrial dysfunction in human islet amyloid polypeptide-induced apoptosis in INS-1E pancreatic beta cells: An effect attenuated by phycocyanin.

Li XL, Chen T, Wong YS, Xu G, Fan RR, Zhao HL, Chan JC.

Int J Biochem Cell Biol. 2011 Apr;43(4):525-34. doi: 10.1016/j.biocel.2010.12.008.

PMID:
21163363
17.

Insulin counteracts glucotoxic effects by suppressing thioredoxin-interacting protein production in INS-1E beta cells and in Psammomys obesus pancreatic islets.

Shaked M, Ketzinel-Gilad M, Ariav Y, Cerasi E, Kaiser N, Leibowitz G.

Diabetologia. 2009 Apr;52(4):636-44. doi: 10.1007/s00125-009-1274-2.

PMID:
19214472
18.

Synthesis and Characterization of a Novel Mycophenolic Acid-Quinic Acid Conjugate Serving as Immunosuppressant with Decreased Toxicity.

Peng Y, Dong Y, Mahato RI.

Mol Pharm. 2015 Dec 7;12(12):4445-53. doi: 10.1021/acs.molpharmaceut.5b00639.

PMID:
26529468
19.

Arsenic induces reactive oxygen species-caused neuronal cell apoptosis through JNK/ERK-mediated mitochondria-dependent and GRP 78/CHOP-regulated pathways.

Lu TH, Tseng TJ, Su CC, Tang FC, Yen CC, Liu YY, Yang CY, Wu CC, Chen KL, Hung DZ, Chen YW.

Toxicol Lett. 2014 Jan 3;224(1):130-40. doi: 10.1016/j.toxlet.2013.10.013.

PMID:
24157283
20.

The scaffold protein IB1/JIP-1 is a critical mediator of cytokine-induced apoptosis in pancreatic beta cells.

Haefliger JA, Tawadros T, Meylan L, Gurun SL, Roehrich ME, Martin D, Thorens B, Waeber G.

J Cell Sci. 2003 Apr 15;116(Pt 8):1463-9.

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