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Items: 1 to 20 of 114


Altering cell death pathways as an approach to cure HIV infection.

Badley AD, Sainski A, Wightman F, Lewin SR.

Cell Death Dis. 2013 Jul 11;4:e718. doi: 10.1038/cddis.2013.248. Review.


Modulation of apoptosis and viral latency - an axis to be well understood for successful cure of human immunodeficiency virus.

Timilsina U, Gaur R.

J Gen Virol. 2016 Apr;97(4):813-24. doi: 10.1099/jgv.0.000402. Epub 2016 Jan 13. Review.


Finding a cure for HIV: will it ever be achievable?

Lewin SR, Evans VA, Elliott JH, Spire B, Chomont N.

J Int AIDS Soc. 2011 Jan 24;14:4. doi: 10.1186/1758-2652-14-4.


Select host restriction factors are associated with HIV persistence during antiretroviral therapy.

Abdel-Mohsen M, Wang C, Strain MC, Lada SM, Deng X, Cockerham LR, Pilcher CD, Hecht FM, Liegler T, Richman DD, Deeks SG, Pillai SK.

AIDS. 2015 Feb 20;29(4):411-20. doi: 10.1097/QAD.0000000000000572.


Persistence of wild-type virus and lack of temporal structure in the latent reservoir for human immunodeficiency virus type 1 in pediatric patients with extensive antiretroviral exposure.

Ruff CT, Ray SC, Kwon P, Zinn R, Pendleton A, Hutton N, Ashworth R, Gange S, Quinn TC, Siliciano RF, Persaud D.

J Virol. 2002 Sep;76(18):9481-92.


Recent developments in the search for a cure for HIV-1 infection: targeting the latent reservoir for HIV-1.

Siliciano JD, Siliciano RF.

J Allergy Clin Immunol. 2014 Jul;134(1):12-9. doi: 10.1016/j.jaci.2014.05.026. Epub 2014 Jun 26. Review.


Eradicating HIV-1 infection: seeking to clear a persistent pathogen.

Archin NM, Sung JM, Garrido C, Soriano-Sarabia N, Margolis DM.

Nat Rev Microbiol. 2014 Nov;12(11):750-64. doi: 10.1038/nrmicro3352. Review.


From reactivation of latent HIV-1 to elimination of the latent reservoir: the presence of multiple barriers to viral eradication.

Shan L, Siliciano RF.

Bioessays. 2013 Jun;35(6):544-52. doi: 10.1002/bies.201200170. Epub 2013 Apr 24. Review.


Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations.

Deng K, Pertea M, Rongvaux A, Wang L, Durand CM, Ghiaur G, Lai J, McHugh HL, Hao H, Zhang H, Margolick JB, Gurer C, Murphy AJ, Valenzuela DM, Yancopoulos GD, Deeks SG, Strowig T, Kumar P, Siliciano JD, Salzberg SL, Flavell RA, Shan L, Siliciano RF.

Nature. 2015 Jan 15;517(7534):381-5. doi: 10.1038/nature14053. Epub 2015 Jan 7.


Finding a cure for human immunodeficiency virus-1 infection.

Blankson JN, Siliciano JD, Siliciano RF.

Infect Dis Clin North Am. 2014 Dec;28(4):633-50. doi: 10.1016/j.idc.2014.08.007. Epub 2014 Sep 30. Review.


Stable Phenotypic Changes of the Host T Cells Are Essential to the Long-Term Stability of Latent HIV-1 Infection.

Seu L, Sabbaj S, Duverger A, Wagner F, Anderson JC, Davies E, Wolschendorf F, Willey CD, Saag MS, Goepfert P, Kutsch O.

J Virol. 2015 Jul;89(13):6656-72. doi: 10.1128/JVI.00571-15. Epub 2015 Apr 15.


Latent HIV-1 infection of resting CD4⁺ T cells in the humanized Rag2⁻/⁻ γc⁻/⁻ mouse.

Choudhary SK, Archin NM, Cheema M, Dahl NP, Garcia JV, Margolis DM.

J Virol. 2012 Jan;86(1):114-20. doi: 10.1128/JVI.05590-11. Epub 2011 Oct 19.


Directly infected resting CD4+T cells can produce HIV Gag without spreading infection in a model of HIV latency.

Pace MJ, Graf EH, Agosto LM, Mexas AM, Male F, Brady T, Bushman FD, O'Doherty U.

PLoS Pathog. 2012;8(7):e1002818. doi: 10.1371/journal.ppat.1002818. Epub 2012 Jul 26.


Reactivation Kinetics of HIV-1 and Susceptibility of Reactivated Latently Infected CD4+ T Cells to HIV-1-Specific CD8+ T Cells.

Walker-Sperling VE, Cohen VJ, Tarwater PM, Blankson JN.

J Virol. 2015 Sep;89(18):9631-8. doi: 10.1128/JVI.01454-15. Epub 2015 Jul 15.


Early establishment of a pool of latently infected, resting CD4(+) T cells during primary HIV-1 infection.

Chun TW, Engel D, Berrey MM, Shea T, Corey L, Fauci AS.

Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8869-73.


Residual inflammation and viral reservoirs: alliance against an HIV cure.

Massanella M, Fromentin R, Chomont N.

Curr Opin HIV AIDS. 2016 Mar;11(2):234-41. doi: 10.1097/COH.0000000000000230. Review.


HIV reservoirs and the possibility of a cure for HIV infection.

Palmer S, Josefsson L, Coffin JM.

J Intern Med. 2011 Dec;270(6):550-60. doi: 10.1111/j.1365-2796.2011.02457.x. Epub 2011 Oct 27. Review.


Curing HIV: Pharmacologic approaches to target HIV-1 latency.

Choudhary SK, Margolis DM.

Annu Rev Pharmacol Toxicol. 2011;51:397-418. doi: 10.1146/annurev-pharmtox-010510-100237. Review.


HIV DNA subspecies persist in both activated and resting memory CD4+ T cells during antiretroviral therapy.

Murray JM, Zaunders JJ, McBride KL, Xu Y, Bailey M, Suzuki K, Cooper DA, Emery S, Kelleher AD, Koelsch KK; PINT Study Team.

J Virol. 2014 Mar;88(6):3516-26. doi: 10.1128/JVI.03331-13. Epub 2014 Jan 8.

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