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Items: 1 to 20 of 200

1.

Paternal obesity initiates metabolic disturbances in two generations of mice with incomplete penetrance to the F2 generation and alters the transcriptional profile of testis and sperm microRNA content.

Fullston T, Ohlsson Teague EM, Palmer NO, DeBlasio MJ, Mitchell M, Corbett M, Print CG, Owens JA, Lane M.

FASEB J. 2013 Oct;27(10):4226-43. doi: 10.1096/fj.12-224048. Epub 2013 Jul 11.

PMID:
23845863
2.

Sperm microRNA Content Is Altered in a Mouse Model of Male Obesity, but the Same Suite of microRNAs Are Not Altered in Offspring's Sperm.

Fullston T, Ohlsson-Teague EM, Print CG, Sandeman LY, Lane M.

PLoS One. 2016 Nov 4;11(11):e0166076. doi: 10.1371/journal.pone.0166076. eCollection 2016.

3.

Diet-induced paternal obesity in the absence of diabetes diminishes the reproductive health of two subsequent generations of mice.

Fullston T, Palmer NO, Owens JA, Mitchell M, Bakos HW, Lane M.

Hum Reprod. 2012 May;27(5):1391-400. doi: 10.1093/humrep/des030. Epub 2012 Feb 21.

PMID:
22357767
4.

Preconception diet or exercise intervention in obese fathers normalizes sperm microRNA profile and metabolic syndrome in female offspring.

McPherson NO, Owens JA, Fullston T, Lane M.

Am J Physiol Endocrinol Metab. 2015 May 1;308(9):E805-21. doi: 10.1152/ajpendo.00013.2015. Epub 2015 Feb 17.

PMID:
25690453
5.

Resistance to high-fat diet in the female progeny of obese mice fed a control diet during the periconceptual, gestation, and lactation periods.

Gallou-Kabani C, Vigé A, Gross MS, Boileau C, Rabes JP, Fruchart-Najib J, Jais JP, Junien C.

Am J Physiol Endocrinol Metab. 2007 Apr;292(4):E1095-100. Epub 2006 Dec 12.

PMID:
17164437
6.

Diet-induced obesity leads to metabolic dysregulation in offspring via endoplasmic reticulum stress in a sex-specific manner.

Park JH, Yoo Y, Cho M, Lim J, Lindroth AM, Park YJ.

Int J Obes (Lond). 2017 Aug 16. doi: 10.1038/ijo.2017.203. [Epub ahead of print]

PMID:
28811650
7.

Paternal obesity induces metabolic and sperm disturbances in male offspring that are exacerbated by their exposure to an "obesogenic" diet.

Fullston T, McPherson NO, Owens JA, Kang WX, Sandeman LY, Lane M.

Physiol Rep. 2015 Mar;3(3). pii: e12336. doi: 10.14814/phy2.12336.

8.

Obese father's metabolic state, adiposity, and reproductive capacity indicate son's reproductive health.

McPherson NO, Fullston T, Bakos HW, Setchell BP, Lane M.

Fertil Steril. 2014 Mar;101(3):865-73. doi: 10.1016/j.fertnstert.2013.12.007. Epub 2014 Jan 11.

PMID:
24424359
10.

Intergenerational impact of paternal lifetime exposures to both folic acid deficiency and supplementation on reproductive outcomes and imprinted gene methylation.

Ly L, Chan D, Aarabi M, Landry M, Behan NA, MacFarlane AJ, Trasler J.

Mol Hum Reprod. 2017 Jul 1;23(7):461-477. doi: 10.1093/molehr/gax029.

PMID:
28535307
11.

Diet and exercise in an obese mouse fed a high-fat diet improve metabolic health and reverse perturbed sperm function.

Palmer NO, Bakos HW, Owens JA, Setchell BP, Lane M.

Am J Physiol Endocrinol Metab. 2012 Apr 1;302(7):E768-80. doi: 10.1152/ajpendo.00401.2011. Epub 2012 Jan 17.

PMID:
22252945
12.

Male mice produced by in vitro culture have reduced fertility and transmit organomegaly and glucose intolerance to their male offspring.

Calle A, Miranda A, Fernandez-Gonzalez R, Pericuesta E, Laguna R, Gutierrez-Adan A.

Biol Reprod. 2012 Aug 9;87(2):34. doi: 10.1095/biolreprod.112.100743. Print 2012 Aug.

PMID:
22649070
13.

Oxidative stress in mouse sperm impairs embryo development, fetal growth and alters adiposity and glucose regulation in female offspring.

Lane M, McPherson NO, Fullston T, Spillane M, Sandeman L, Kang WX, Zander-Fox DL.

PLoS One. 2014 Jul 9;9(7):e100832. doi: 10.1371/journal.pone.0100832. eCollection 2014.

14.

Paternal BPA exposure in early life alters Igf2 epigenetic status in sperm and induces pancreatic impairment in rat offspring.

Mao Z, Xia W, Chang H, Huo W, Li Y, Xu S.

Toxicol Lett. 2015 Nov 4;238(3):30-8. doi: 10.1016/j.toxlet.2015.08.009. Epub 2015 Aug 11.

PMID:
26276081
15.

Elevated paternal glucocorticoid exposure alters the small noncoding RNA profile in sperm and modifies anxiety and depressive phenotypes in the offspring.

Short AK, Fennell KA, Perreau VM, Fox A, O'Bryan MK, Kim JH, Bredy TW, Pang TY, Hannan AJ.

Transl Psychiatry. 2016 Jun 14;6(6):e837. doi: 10.1038/tp.2016.109.

16.

Accumulation of endoplasmic reticulum stress and lipogenesis in the liver through generational effects of high fat diets.

Li J, Huang J, Li JS, Chen H, Huang K, Zheng L.

J Hepatol. 2012 Apr;56(4):900-7. doi: 10.1016/j.jhep.2011.10.018. Epub 2011 Dec 13.

PMID:
22173165
17.

Paternal long-term exercise programs offspring for low energy expenditure and increased risk for obesity in mice.

Murashov AK, Pak ES, Koury M, Ajmera A, Jeyakumar M, Parker M, Williams O, Ding J, Walters D, Neufer PD.

FASEB J. 2016 Feb;30(2):775-84. doi: 10.1096/fj.15-274274. Epub 2015 Oct 27.

18.

The effect of paternal diet-induced obesity on sperm function and fertilization in a mouse model.

Bakos HW, Mitchell M, Setchell BP, Lane M.

Int J Androl. 2011 Oct;34(5 Pt 1):402-10. doi: 10.1111/j.1365-2605.2010.01092.x. Epub 2010 Jul 23.

PMID:
20649934
19.

Transgenerational epigenetic programming via sperm microRNA recapitulates effects of paternal stress.

Rodgers AB, Morgan CP, Leu NA, Bale TL.

Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):13699-704. doi: 10.1073/pnas.1508347112. Epub 2015 Oct 19.

20.

Sex differences in transgenerational alterations of growth and metabolism in progeny (F2) of female offspring (F1) of rats fed a low protein diet during pregnancy and lactation.

Zambrano E, Martínez-Samayoa PM, Bautista CJ, Deás M, Guillén L, Rodríguez-González GL, Guzmán C, Larrea F, Nathanielsz PW.

J Physiol. 2005 Jul 1;566(Pt 1):225-36. Epub 2005 Apr 28.

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