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Items: 1 to 20 of 160

1.

System-based identification of toxicity pathways associated with multi-walled carbon nanotube-induced pathological responses.

Snyder-Talkington BN, Dymacek J, Porter DW, Wolfarth MG, Mercer RR, Pacurari M, Denvir J, Castranova V, Qian Y, Guo NL.

Toxicol Appl Pharmacol. 2013 Oct 15;272(2):476-89. doi: 10.1016/j.taap.2013.06.026. Epub 2013 Jul 8.

2.

mRNA and miRNA regulatory networks reflective of multi-walled carbon nanotube-induced lung inflammatory and fibrotic pathologies in mice.

Dymacek J, Snyder-Talkington BN, Porter DW, Mercer RR, Wolfarth MG, Castranova V, Qian Y, Guo NL.

Toxicol Sci. 2015 Mar;144(1):51-64. doi: 10.1093/toxsci/kfu262. Epub 2014 Dec 18.

3.

Distribution and fibrotic response following inhalation exposure to multi-walled carbon nanotubes.

Mercer RR, Scabilloni JF, Hubbs AF, Battelli LA, McKinney W, Friend S, Wolfarth MG, Andrew M, Castranova V, Porter DW.

Part Fibre Toxicol. 2013 Jul 30;10:33. doi: 10.1186/1743-8977-10-33.

4.

In vivo activation of a T helper 2-driven innate immune response in lung fibrosis induced by multi-walled carbon nanotubes.

Dong J, Ma Q.

Arch Toxicol. 2016 Sep;90(9):2231-48. doi: 10.1007/s00204-016-1711-1. Epub 2016 Apr 22.

5.

Mouse pulmonary dose- and time course-responses induced by exposure to multi-walled carbon nanotubes.

Porter DW, Hubbs AF, Mercer RR, Wu N, Wolfarth MG, Sriram K, Leonard S, Battelli L, Schwegler-Berry D, Friend S, Andrew M, Chen BT, Tsuruoka S, Endo M, Castranova V.

Toxicology. 2010 Mar 10;269(2-3):136-47. doi: 10.1016/j.tox.2009.10.017. Epub 2009 Oct 24.

PMID:
19857541
6.

Multiwalled carbon nanotube-induced pulmonary inflammatory and fibrotic responses and genomic changes following aspiration exposure in mice: A 1-year postexposure study.

Snyder-Talkington BN, Dong C, Porter DW, Ducatman B, Wolfarth MG, Andrew M, Battelli L, Raese R, Castranova V, Guo NL, Qian Y.

J Toxicol Environ Health A. 2016;79(8):352-66. doi: 10.1080/15287394.2016.1159635. Epub 2016 Apr 19.

7.

Pulmonary toxicity of multi-walled carbon nanotubes (Baytubes) relative to alpha-quartz following a single 6h inhalation exposure of rats and a 3 months post-exposure period.

Ellinger-Ziegelbauer H, Pauluhn J.

Toxicology. 2009 Dec 21;266(1-3):16-29. doi: 10.1016/j.tox.2009.10.007. Epub 2009 Oct 28.

PMID:
19836432
8.

Multi-walled carbon nanotubes directly induce epithelial-mesenchymal transition in human bronchial epithelial cells via the TGF-β-mediated Akt/GSK-3β/SNAIL-1 signalling pathway.

Polimeni M, Gulino GR, Gazzano E, Kopecka J, Marucco A, Fenoglio I, Cesano F, Campagnolo L, Magrini A, Pietroiusti A, Ghigo D, Aldieri E.

Part Fibre Toxicol. 2016 Jun 1;13(1):27. doi: 10.1186/s12989-016-0138-4.

9.

MWCNTs of different physicochemical properties cause similar inflammatory responses, but differences in transcriptional and histological markers of fibrosis in mouse lungs.

Poulsen SS, Saber AT, Williams A, Andersen O, Købler C, Atluri R, Pozzebon ME, Mucelli SP, Simion M, Rickerby D, Mortensen A, Jackson P, Kyjovska ZO, Mølhave K, Jacobsen NR, Jensen KA, Yauk CL, Wallin H, Halappanavar S, Vogel U.

Toxicol Appl Pharmacol. 2015 Apr 1;284(1):16-32. doi: 10.1016/j.taap.2014.12.011. Epub 2014 Dec 29.

10.

Pathologic and molecular profiling of rapid-onset fibrosis and inflammation induced by multi-walled carbon nanotubes.

Dong J, Porter DW, Batteli LA, Wolfarth MG, Richardson DL, Ma Q.

Arch Toxicol. 2015 Apr;89(4):621-33. doi: 10.1007/s00204-014-1428-y. Epub 2014 Dec 16.

PMID:
25510677
11.

Nano-risk Science: application of toxicogenomics in an adverse outcome pathway framework for risk assessment of multi-walled carbon nanotubes.

Labib S, Williams A, Yauk CL, Nikota JK, Wallin H, Vogel U, Halappanavar S.

Part Fibre Toxicol. 2016 Mar 15;13:15. doi: 10.1186/s12989-016-0125-9.

12.

Multi-walled carbon nanotube instillation impairs pulmonary function in C57BL/6 mice.

Wang X, Katwa P, Podila R, Chen P, Ke PC, Rao AM, Walters DM, Wingard CJ, Brown JM.

Part Fibre Toxicol. 2011 Aug 18;8:24. doi: 10.1186/1743-8977-8-24.

13.

Acute pulmonary dose-responses to inhaled multi-walled carbon nanotubes.

Porter DW, Hubbs AF, Chen BT, McKinney W, Mercer RR, Wolfarth MG, Battelli L, Wu N, Sriram K, Leonard S, Andrew M, Willard P, Tsuruoka S, Endo M, Tsukada T, Munekane F, Frazer DG, Castranova V.

Nanotoxicology. 2013 Nov;7(7):1179-94. doi: 10.3109/17435390.2012.719649. Epub 2012 Sep 13. Erratum in: Nanotoxicology. 2013 Dec;7(8):1399.

14.

Epithelial-mesenchymal transition involved in pulmonary fibrosis induced by multi-walled carbon nanotubes via TGF-beta/Smad signaling pathway.

Chen T, Nie H, Gao X, Yang J, Pu J, Chen Z, Cui X, Wang Y, Wang H, Jia G.

Toxicol Lett. 2014 Apr 21;226(2):150-62. doi: 10.1016/j.toxlet.2014.02.004. Epub 2014 Feb 12.

PMID:
24530353
15.

Multi-walled carbon nanotube physicochemical properties predict pulmonary inflammation and genotoxicity.

Poulsen SS, Jackson P, Kling K, Knudsen KB, Skaug V, Kyjovska ZO, Thomsen BL, Clausen PA, Atluri R, Berthing T, Bengtson S, Wolff H, Jensen KA, Wallin H, Vogel U.

Nanotoxicology. 2016 Nov;10(9):1263-75. doi: 10.1080/17435390.2016.1202351. Epub 2016 Jul 7.

16.

Suppression of basal and carbon nanotube-induced oxidative stress, inflammation and fibrosis in mouse lungs by Nrf2.

Dong J, Ma Q.

Nanotoxicology. 2016 Aug;10(6):699-709. doi: 10.3109/17435390.2015.1110758. Epub 2015 Nov 23.

PMID:
26592091
17.

Multi-walled carbon nanotube-induced genotoxic, inflammatory and pro-fibrotic responses in mice: Investigating the mechanisms of pulmonary carcinogenesis.

Rahman L, Jacobsen NR, Aziz SA, Wu D, Williams A, Yauk CL, White P, Wallin H, Vogel U, Halappanavar S.

Mutat Res. 2017 Nov;823:28-44. doi: 10.1016/j.mrgentox.2017.08.005. Epub 2017 Sep 8.

18.

Transcriptomic analysis reveals novel mechanistic insight into murine biological responses to multi-walled carbon nanotubes in lungs and cultured lung epithelial cells.

Søs Poulsen S, Jacobsen NR, Labib S, Wu D, Husain M, Williams A, Bøgelund JP, Andersen O, Købler C, Mølhave K, Kyjovska ZO, Saber AT, Wallin H, Yauk CL, Vogel U, Halappanavar S.

PLoS One. 2013 Nov 19;8(11):e80452. doi: 10.1371/journal.pone.0080452. eCollection 2013.

19.

Comparative proteomics and pulmonary toxicity of instilled single-walled carbon nanotubes, crocidolite asbestos, and ultrafine carbon black in mice.

Teeguarden JG, Webb-Robertson BJ, Waters KM, Murray AR, Kisin ER, Varnum SM, Jacobs JM, Pounds JG, Zanger RC, Shvedova AA.

Toxicol Sci. 2011 Mar;120(1):123-35. doi: 10.1093/toxsci/kfq363. Epub 2010 Dec 6.

20.

Long-term effects of carbon containing engineered nanomaterials and asbestos in the lung: one year postexposure comparisons.

Shvedova AA, Yanamala N, Kisin ER, Tkach AV, Murray AR, Hubbs A, Chirila MM, Keohavong P, Sycheva LP, Kagan VE, Castranova V.

Am J Physiol Lung Cell Mol Physiol. 2014 Jan;306(2):L170-82. doi: 10.1152/ajplung.00167.2013. Epub 2013 Nov 8.

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