Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 98


A rare population of CD24(+)ITGB4(+)Notch(hi) cells drives tumor propagation in NSCLC and requires Notch3 for self-renewal.

Zheng Y, de la Cruz CC, Sayles LC, Alleyne-Chin C, Vaka D, Knaak TD, Bigos M, Xu Y, Hoang CD, Shrager JB, Fehling HJ, French D, Forrest W, Jiang Z, Carano RA, Barck KH, Jackson EL, Sweet-Cordero EA.

Cancer Cell. 2013 Jul 8;24(1):59-74. doi: 10.1016/j.ccr.2013.05.021.


Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling.

Sullivan JP, Spinola M, Dodge M, Raso MG, Behrens C, Gao B, Schuster K, Shao C, Larsen JE, Sullivan LA, Honorio S, Xie Y, Scaglioni PP, DiMaio JM, Gazdar AF, Shay JW, Wistuba II, Minna JD.

Cancer Res. 2010 Dec 1;70(23):9937-48. doi: 10.1158/0008-5472.CAN-10-0881. Epub 2010 Nov 30.


Evaluation of role of Notch3 signaling pathway in human lung cancer cells.

Hassan WA, Yoshida R, Kudoh S, Motooka Y, Ito T.

J Cancer Res Clin Oncol. 2016 May;142(5):981-93. doi: 10.1007/s00432-016-2117-4. Epub 2016 Feb 2.


Notch3 is important for TGF-β-induced epithelial-mesenchymal transition in non-small cell lung cancer bone metastasis by regulating ZEB-1.

Liu L, Chen X, Wang Y, Qu Z, Lu Q, Zhao J, Yan X, Zhang H, Zhou Y.

Cancer Gene Ther. 2014 Sep;21(9):364-72. doi: 10.1038/cgt.2014.39. Epub 2014 Aug 1.


Notch signaling contributes to lung cancer clonogenic capacity in vitro but may be circumvented in tumorigenesis in vivo.

Osanyingbemi-Obidi J, Dobromilskaya I, Illei PB, Hann CL, Rudin CM.

Mol Cancer Res. 2011 Dec;9(12):1746-54. doi: 10.1158/1541-7786.MCR-11-0286. Epub 2011 Oct 12.


Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer.

Xiong J, Zhang X, Chen X, Wei Y, Lu DG, Han YW, Xu J, Yu D.

Oncotarget. 2017 Feb 21;8(8):13157-13165. doi: 10.18632/oncotarget.14483.


Notch 3 protein, not its gene polymorphism, is associated with the chemotherapy response and prognosis of advanced NSCLC patients.

Shi C, Qian J, Ma M, Zhang Y, Han B.

Cell Physiol Biochem. 2014;34(3):743-52. doi: 10.1159/000363039. Epub 2014 Aug 19.


Gamma-secretase inhibitor prevents Notch3 activation and reduces proliferation in human lung cancers.

Konishi J, Kawaguchi KS, Vo H, Haruki N, Gonzalez A, Carbone DP, Dang TP.

Cancer Res. 2007 Sep 1;67(17):8051-7.


Evidence of the cross talk between Wnt and Notch signaling pathways in non-small-cell lung cancer (NSCLC): Notch3-siRNA weakens the effect of LiCl on the cell cycle of NSCLC cell lines.

Li C, Zhang Y, Lu Y, Cui Z, Yu M, Zhang S, Xue X.

J Cancer Res Clin Oncol. 2011 May;137(5):771-8. doi: 10.1007/s00432-010-0934-4. Epub 2010 Jul 8.


Meta-analysis reveals the correlation of Notch signaling with non-small cell lung cancer progression and prognosis.

Yuan X, Wu H, Xu H, Han N, Chu Q, Yu S, Chen Y, Wu K.

Sci Rep. 2015 May 21;5:10338. doi: 10.1038/srep10338.


Elevated integrin α6β4 expression is associated with venous invasion and decreased overall survival in non-small cell lung cancer.

Stewart RL, West D, Wang C, Weiss HL, Gal T, Durbin EB, O'Connor W, Chen M, O'Connor KL.

Hum Pathol. 2016 Aug;54:174-83. doi: 10.1016/j.humpath.2016.04.003. Epub 2016 Apr 20.


Wnt3a increases the metastatic potential of non-small cell lung cancer cells in vitro in part via its upregulation of Notch3.

Li C, Song G, Zhang S, Wang E, Cui Z.

Oncol Rep. 2015 Mar;33(3):1207-14. doi: 10.3892/or.2014.3700. Epub 2014 Dec 30.


Notch3 overexpression associates with poor prognosis in human non-small-cell lung cancer.

Ye YZ, Zhang ZH, Fan XY, Xu XL, Chen ML, Chang BW, Zhang YB.

Med Oncol. 2013;30(2):595. doi: 10.1007/s12032-013-0595-7. Epub 2013 May 7. Erratum in: Med Oncol. 2013 Dec;30(4):716.


High NOTCH activity induces radiation resistance in non small cell lung cancer.

Theys J, Yahyanejad S, Habets R, Span P, Dubois L, Paesmans K, Kattenbeld B, Cleutjens J, Groot AJ, Schuurbiers OCJ, Lambin P, Bussink J, Vooijs M.

Radiother Oncol. 2013 Sep;108(3):440-445. doi: 10.1016/j.radonc.2013.06.020. Epub 2013 Jul 25.


Blockade of Notch3 inhibits the stem-like property and is associated with ALDH1A1 and CD44 via autophagy in non-small lung cancer.

Ma Y, Li M, Si J, Xiong Y, Lu F, Zhang J, Zhang L, Zhang P, Yang Y.

Int J Oncol. 2016 Jun;48(6):2349-58. doi: 10.3892/ijo.2016.3464. Epub 2016 Mar 30.


Identification and Targeting of Long-Term Tumor-Propagating Cells in Small Cell Lung Cancer.

Jahchan NS, Lim JS, Bola B, Morris K, Seitz G, Tran KQ, Xu L, Trapani F, Morrow CJ, Cristea S, Coles GL, Yang D, Vaka D, Kareta MS, George J, Mazur PK, Nguyen T, Anderson WC, Dylla SJ, Blackhall F, Peifer M, Dive C, Sage J.

Cell Rep. 2016 Jul 19;16(3):644-56. doi: 10.1016/j.celrep.2016.06.021. Epub 2016 Jun 30.


NOTCH3 expression is linked to breast cancer seeding and distant metastasis.

Leontovich AA, Jalalirad M, Salisbury JL, Mills L, Haddox C, Schroeder M, Tuma A, Guicciardi ME, Zammataro L, Gambino MW, Amato A, Di Leonardo A, McCubrey J, Lange CA, Liu M, Haddad T, Goetz M, Boughey J, Sarkaria J, Wang L, Ingle JN, Galanis E, D'Assoro AB.

Breast Cancer Res. 2018 Sep 4;20(1):105. doi: 10.1186/s13058-018-1020-0.


NOTCH3 signaling regulates MUSASHI-1 expression in metastatic colorectal cancer cells.

Pastò A, Serafin V, Pilotto G, Lago C, Bellio C, Trusolino L, Bertotti A, Hoey T, Plateroti M, Esposito G, Pinazza M, Agostini M, Nitti D, Amadori A, Indraccolo S.

Cancer Res. 2014 Apr 1;74(7):2106-18. doi: 10.1158/0008-5472.CAN-13-2022. Epub 2014 Feb 13.


Tumor-propagating cells and Yap/Taz activity contribute to lung tumor progression and metastasis.

Lau AN, Curtis SJ, Fillmore CM, Rowbotham SP, Mohseni M, Wagner DE, Beede AM, Montoro DT, Sinkevicius KW, Walton ZE, Barrios J, Weiss DJ, Camargo FD, Wong KK, Kim CF.

EMBO J. 2014 Mar 3;33(5):468-81. doi: 10.1002/embj.201386082. Epub 2014 Feb 4. Erratum in: EMBO J. 2014 Jul 1;33(13):1502.


Self-renewal of CD133(hi) cells by IL6/Notch3 signalling regulates endocrine resistance in metastatic breast cancer.

Sansone P, Ceccarelli C, Berishaj M, Chang Q, Rajasekhar VK, Perna F, Bowman RL, Vidone M, Daly L, Nnoli J, Santini D, Taffurelli M, Shih NN, Feldman M, Mao JJ, Colameco C, Chen J, DeMichele A, Fabbri N, Healey JH, Cricca M, Gasparre G, Lyden D, Bonafé M, Bromberg J.

Nat Commun. 2016 Feb 9;7:10442. doi: 10.1038/ncomms10442.

Supplemental Content

Support Center