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Items: 1 to 20 of 190

1.

Spontaneous atopic dermatitis-like symptoms in a/a ma ft/ma ft/J flaky tail mice appear early after birth.

Kypriotou M, Boéchat C, Huber M, Hohl D.

PLoS One. 2013 Jul 3;8(7):e67869. doi: 10.1371/journal.pone.0067869. Print 2013.

2.

Loss of normal profilaggrin and filaggrin in flaky tail (ft/ft) mice: an animal model for the filaggrin-deficient skin disease ichthyosis vulgaris.

Presland RB, Boggess D, Lewis SP, Hull C, Fleckman P, Sundberg JP.

J Invest Dermatol. 2000 Dec;115(6):1072-81.

3.

Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency.

Kezic S, O'Regan GM, Lutter R, Jakasa I, Koster ES, Saunders S, Caspers P, Kemperman PM, Puppels GJ, Sandilands A, Chen H, Campbell LE, Kroboth K, Watson R, Fallon PG, McLean WH, Irvine AD.

J Allergy Clin Immunol. 2012 Apr;129(4):1031-9.e1. doi: 10.1016/j.jaci.2011.12.989. Epub 2012 Feb 8.

4.

A homozygous nonsense mutation in the gene for Tmem79, a component for the lamellar granule secretory system, produces spontaneous eczema in an experimental model of atopic dermatitis.

Sasaki T, Shiohama A, Kubo A, Kawasaki H, Ishida-Yamamoto A, Yamada T, Hachiya T, Shimizu A, Okano H, Kudoh J, Amagai M.

J Allergy Clin Immunol. 2013 Nov;132(5):1111-1120.e4. doi: 10.1016/j.jaci.2013.08.027. Epub 2013 Sep 20.

PMID:
24060273
5.

IL-1β induces thymic stromal lymphopoietin and an atopic dermatitis-like phenotype in reconstructed healthy human epidermis.

Bernard M, Carrasco C, Laoubi L, Guiraud B, Rozières A, Goujon C, Duplan H, Bessou-Touya S, Nicolas JF, Vocanson M, Galliano MF.

J Pathol. 2017 Jun;242(2):234-245. doi: 10.1002/path.4887. Epub 2017 Apr 6.

PMID:
28191908
6.

Spontaneous atopic dermatitis is mediated by innate immunity, with the secondary lung inflammation of the atopic march requiring adaptive immunity.

Saunders SP, Moran T, Floudas A, Wurlod F, Kaszlikowska A, Salimi M, Quinn EM, Oliphant CJ, Núñez G, McManus R, Hams E, Irvine AD, McKenzie AN, Ogg GS, Fallon PG.

J Allergy Clin Immunol. 2016 Feb;137(2):482-91. doi: 10.1016/j.jaci.2015.06.045. Epub 2015 Aug 20.

7.

Protease activity enhances production of thymic stromal lymphopoietin and basophil accumulation in flaky tail mice.

Moniaga CS, Jeong SK, Egawa G, Nakajima S, Hara-Chikuma M, Jeon JE, Lee SH, Hibino T, Miyachi Y, Kabashima K.

Am J Pathol. 2013 Mar;182(3):841-51. doi: 10.1016/j.ajpath.2012.11.039. Epub 2013 Jan 17.

PMID:
23333753
8.

Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects.

Saunders SP, Goh CS, Brown SJ, Palmer CN, Porter RM, Cole C, Campbell LE, Gierlinski M, Barton GJ, Schneider G, Balmain A, Prescott AR, Weidinger S, Baurecht H, Kabesch M, Gieger C, Lee YA, Tavendale R, Mukhopadhyay S, Turner SW, Madhok VB, Sullivan FM, Relton C, Burn J, Meggitt S, Smith CH, Allen MA, Barker JN, Reynolds NJ, Cordell HJ, Irvine AD, McLean WH, Sandilands A, Fallon PG.

J Allergy Clin Immunol. 2013 Nov;132(5):1121-9. doi: 10.1016/j.jaci.2013.08.046. Epub 2013 Sep 29.

9.

Analyses of FLG mutation frequency and filaggrin expression in isolated ichthyosis vulgaris (IV) and atopic dermatitis-associated IV.

Li M, Cheng R, Shi M, Liu J, Zhang G, Liu Q, Yu H, Yao Z.

Br J Dermatol. 2013 Jun;168(6):1335-8. doi: 10.1111/bjd.12206. Epub 2013 Apr 1.

PMID:
23290076
10.

Filaggrin in atopic dermatitis: flaky tail mice as a novel model for developing drug targets in atopic dermatitis.

Moniaga CS, Kabashima K.

Inflamm Allergy Drug Targets. 2011 Dec;10(6):477-85. Review.

PMID:
21999178
11.

Filaggrin genotype determines functional and molecular alterations in skin of patients with atopic dermatitis and ichthyosis vulgaris.

Winge MC, Hoppe T, Berne B, Vahlquist A, Nordenskjöld M, Bradley M, Törmä H.

PLoS One. 2011;6(12):e28254. doi: 10.1371/journal.pone.0028254. Epub 2011 Dec 2.

12.

Novel filaggrin mutation but no other loss-of-function variants found in Ethiopian patients with atopic dermatitis.

Winge MC, Bilcha KD, Liedén A, Shibeshi D, Sandilands A, Wahlgren CF, McLean WH, Nordenskjöld M, Bradley M.

Br J Dermatol. 2011 Nov;165(5):1074-80. doi: 10.1111/j.1365-2133.2011.10475.x. Epub 2011 Oct 17.

PMID:
21692775
13.

[Mouse models for spontaneous dermatitis due to impaired skin barrier formation].

Sasaki T, Shiohama A, Amagai M.

Nihon Rinsho Meneki Gakkai Kaishi. 2014;37(3):160-5. Japanese.

14.

Alterations in Epidermal Eicosanoid Metabolism Contribute to Inflammation and Impaired Late Differentiation in FLG-Mutated Atopic Dermatitis.

Blunder S, Rühl R, Moosbrugger-Martinz V, Krimmel C, Geisler A, Zhu H, Crumrine D, Elias PM, Gruber R, Schmuth M, Dubrac S.

J Invest Dermatol. 2017 Mar;137(3):706-715. doi: 10.1016/j.jid.2016.09.034. Epub 2016 Oct 26.

15.

Selective ablation of Ctip2/Bcl11b in epidermal keratinocytes triggers atopic dermatitis-like skin inflammatory responses in adult mice.

Wang Z, Zhang LJ, Guha G, Li S, Kyrylkova K, Kioussi C, Leid M, Ganguli-Indra G, Indra AK.

PLoS One. 2012;7(12):e51262. doi: 10.1371/journal.pone.0051262. Epub 2012 Dec 20.

16.

Filaggrin deficiency promotes the dissemination of cutaneously inoculated vaccinia virus.

Oyoshi MK, Beaupré J, Venturelli N, Lewis CN, Iwakura Y, Geha RS.

J Allergy Clin Immunol. 2015 Jun;135(6):1511-8.e6. doi: 10.1016/j.jaci.2014.12.1923. Epub 2015 Jan 30.

17.

Flaky tail mouse denotes human atopic dermatitis in the steady state and by topical application with Dermatophagoides pteronyssinus extract.

Moniaga CS, Egawa G, Kawasaki H, Hara-Chikuma M, Honda T, Tanizaki H, Nakajima S, Otsuka A, Matsuoka H, Kubo A, Sakabe J, Tokura Y, Miyachi Y, Amagai M, Kabashima K.

Am J Pathol. 2010 May;176(5):2385-93. doi: 10.2353/ajpath.2010.090957. Epub 2010 Mar 19.

18.

Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens.

Scharschmidt TC, Man MQ, Hatano Y, Crumrine D, Gunathilake R, Sundberg JP, Silva KA, Mauro TM, Hupe M, Cho S, Wu Y, Celli A, Schmuth M, Feingold KR, Elias PM.

J Allergy Clin Immunol. 2009 Sep;124(3):496-506, 506.e1-6. doi: 10.1016/j.jaci.2009.06.046.

19.

Filaggrin-deficient mice exhibit TH17-dominated skin inflammation and permissiveness to epicutaneous sensitization with protein antigen.

Oyoshi MK, Murphy GF, Geha RS.

J Allergy Clin Immunol. 2009 Sep;124(3):485-93, 493.e1. doi: 10.1016/j.jaci.2009.05.042. Epub 2009 Aug 8.

20.

A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming.

Fallon PG, Sasaki T, Sandilands A, Campbell LE, Saunders SP, Mangan NE, Callanan JJ, Kawasaki H, Shiohama A, Kubo A, Sundberg JP, Presland RB, Fleckman P, Shimizu N, Kudoh J, Irvine AD, Amagai M, McLean WH.

Nat Genet. 2009 May;41(5):602-8. doi: 10.1038/ng.358. Epub 2009 Apr 6.

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