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Items: 1 to 20 of 105

1.

Identification and structural characterization of a Legionella phosphoinositide phosphatase.

Toulabi L, Wu X, Cheng Y, Mao Y.

J Biol Chem. 2013 Aug 23;288(34):24518-27. doi: 10.1074/jbc.M113.474239.

2.

Structural basis for substrate recognition by a unique Legionella phosphoinositide phosphatase.

Hsu F, Zhu W, Brennan L, Tao L, Luo ZQ, Mao Y.

Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13567-72. doi: 10.1073/pnas.1207903109.

3.

Rab1 guanine nucleotide exchange factor SidM is a major phosphatidylinositol 4-phosphate-binding effector protein of Legionella pneumophila.

Brombacher E, Urwyler S, Ragaz C, Weber SS, Kami K, Overduin M, Hilbi H.

J Biol Chem. 2009 Feb 20;284(8):4846-56. doi: 10.1074/jbc.M807505200.

4.

Legionella pneumophila exploits PI(4)P to anchor secreted effector proteins to the replicative vacuole.

Weber SS, Ragaz C, Reus K, Nyfeler Y, Hilbi H.

PLoS Pathog. 2006 May;2(5):e46.

5.

Structure of the Legionella Virulence Factor, SidC Reveals a Unique PI(4)P-Specific Binding Domain Essential for Its Targeting to the Bacterial Phagosome.

Luo X, Wasilko DJ, Liu Y, Sun J, Wu X, Luo ZQ, Mao Y.

PLoS Pathog. 2015 Jun 12;11(6):e1004965. doi: 10.1371/journal.ppat.1004965.

6.

A type IV translocated Legionella cysteine phytase counteracts intracellular growth restriction by phytate.

Weber S, Stirnimann CU, Wieser M, Frey D, Meier R, Engelhardt S, Li X, Capitani G, Kammerer RA, Hilbi H.

J Biol Chem. 2014 Dec 5;289(49):34175-88. doi: 10.1074/jbc.M114.592568.

7.
8.

Live-cell imaging of phosphoinositide dynamics and membrane architecture during Legionella infection.

Weber S, Wagner M, Hilbi H.

MBio. 2014 Jan 28;5(1):e00839-13. doi: 10.1128/mBio.00839-13.

9.

Domain organization of Legionella effector SetA.

Jank T, Böhmer KE, Tzivelekidis T, Schwan C, Belyi Y, Aktories K.

Cell Microbiol. 2012 Jun;14(6):852-68. doi: 10.1111/j.1462-5822.2012.01761.x.

PMID:
22288428
10.

Phagocytic entry of Legionella pneumophila into macrophages through phosphatidylinositol 3,4,5-trisphosphate-independent pathway.

Harada T, Tanikawa T, Iwasaki Y, Yamada M, Imai Y, Miyake M.

Biol Pharm Bull. 2012;35(9):1460-8.

11.

Legionella pneumophila SidD is a deAMPylase that modifies Rab1.

Tan Y, Luo ZQ.

Nature. 2011 Jul 6;475(7357):506-9. doi: 10.1038/nature10307.

12.
13.

Modulation of phosphoinositide metabolism by pathogenic bacteria.

Hilbi H.

Cell Microbiol. 2006 Nov;8(11):1697-706. Review.

PMID:
16939534
14.

Activation of Ran GTPase by a Legionella effector promotes microtubule polymerization, pathogen vacuole motility and infection.

Rothmeier E, Pfaffinger G, Hoffmann C, Harrison CF, Grabmayr H, Repnik U, Hannemann M, Wölke S, Bausch A, Griffiths G, Müller-Taubenberger A, Itzen A, Hilbi H.

PLoS Pathog. 2013 Sep;9(9):e1003598. doi: 10.1371/journal.ppat.1003598.

15.

LtpD is a novel Legionella pneumophila effector that binds phosphatidylinositol 3-phosphate and inositol monophosphatase IMPA1.

Harding CR, Mattheis C, Mousnier A, Oates CV, Hartland EL, Frankel G, Schroeder GN.

Infect Immun. 2013 Nov;81(11):4261-70. doi: 10.1128/IAI.01054-13.

16.

Structural basis for PI(4)P-specific membrane recruitment of the Legionella pneumophila effector DrrA/SidM.

Del Campo CM, Mishra AK, Wang YH, Roy CR, Janmey PA, Lambright DG.

Structure. 2014 Mar 4;22(3):397-408. doi: 10.1016/j.str.2013.12.018.

17.

Analysis of the Legionella longbeachae genome and transcriptome uncovers unique strategies to cause Legionnaires' disease.

Cazalet C, Gomez-Valero L, Rusniok C, Lomma M, Dervins-Ravault D, Newton HJ, Sansom FM, Jarraud S, Zidane N, Ma L, Bouchier C, Etienne J, Hartland EL, Buchrieser C.

PLoS Genet. 2010 Feb 19;6(2):e1000851. doi: 10.1371/journal.pgen.1000851.

18.

Inhibition of host vacuolar H+-ATPase activity by a Legionella pneumophila effector.

Xu L, Shen X, Bryan A, Banga S, Swanson MS, Luo ZQ.

PLoS Pathog. 2010 Mar 19;6(3):e1000822. doi: 10.1371/journal.ppat.1000822.

19.

Legionella pneumophila Effector LpdA Is a Palmitoylated Phospholipase D Virulence Factor.

Schroeder GN, Aurass P, Oates CV, Tate EW, Hartland EL, Flieger A, Frankel G.

Infect Immun. 2015 Oct;83(10):3989-4002. doi: 10.1128/IAI.00785-15.

20.

The machinery at endoplasmic reticulum-plasma membrane contact sites contributes to spatial regulation of multiple Legionella effector proteins.

Hubber A, Arasaki K, Nakatsu F, Hardiman C, Lambright D, De Camilli P, Nagai H, Roy CR.

PLoS Pathog. 2014 Jul 3;10(7):e1004222. doi: 10.1371/journal.ppat.1004222.

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