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Caspase-2 short isoform interacts with membrane-associated cytoskeleton proteins to inhibit apoptosis.

Han C, Zhao R, Kroger J, Qu M, Wani AA, Wang QE.

PLoS One. 2013 Jul 1;8(7):e67033. doi: 10.1371/journal.pone.0067033. Print 2013.


Nucleotide excision repair factor XPC enhances DNA damage-induced apoptosis by downregulating the antiapoptotic short isoform of caspase-2.

Wang QE, Han C, Zhang B, Sabapathy K, Wani AA.

Cancer Res. 2012 Feb 1;72(3):666-75. doi: 10.1158/0008-5472.CAN-11-2774. Epub 2011 Dec 15.


Identification of a caspase-2 isoform that behaves as an endogenous inhibitor of the caspase cascade.

Droin N, Beauchemin M, Solary E, Bertrand R.

Cancer Res. 2000 Dec 15;60(24):7039-47.


Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis.

Jänicke RU, Ng P, Sprengart ML, Porter AG.

J Biol Chem. 1998 Jun 19;273(25):15540-5.


Calpain-mediated processing of p53-associated parkin-like cytoplasmic protein (PARC) affects chemosensitivity of human ovarian cancer cells by promoting p53 subcellular trafficking.

Woo MG, Xue K, Liu J, McBride H, Tsang BK.

J Biol Chem. 2012 Feb 3;287(6):3963-75. doi: 10.1074/jbc.M111.314765. Epub 2011 Nov 23.


Downregulation of LRRC8A protects human ovarian and alveolar carcinoma cells against Cisplatin-induced expression of p53, MDM2, p21Waf1/Cip1, and Caspase-9/-3 activation.

Sørensen BH, Nielsen D, Thorsteinsdottir UA, Hoffmann EK, Lambert IH.

Am J Physiol Cell Physiol. 2016 Jun 1;310(11):C857-73. doi: 10.1152/ajpcell.00256.2015. Epub 2016 Mar 16.


Over-expression of PTEN sensitizes human ovarian cancer cells to cisplatin-induced apoptosis in a p53-dependent manner.

Yan X, Fraser M, Qiu Q, Tsang BK.

Gynecol Oncol. 2006 Aug;102(2):348-55. Epub 2006 Mar 20.


Selective inhibition of tumor cell associated Vacuolar-ATPase 'a2' isoform overcomes cisplatin resistance in ovarian cancer cells.

Kulshrestha A, Katara GK, Ginter J, Pamarthy S, Ibrahim SA, Jaiswal MK, Sandulescu C, Periakaruppan R, Dolan J, Gilman-Sachs A, Beaman KD.

Mol Oncol. 2016 Jun;10(6):789-805. doi: 10.1016/j.molonc.2016.01.003. Epub 2016 Jan 29.


ABCF2, an Nrf2 target gene, contributes to cisplatin resistance in ovarian cancer cells.

Bao L, Wu J, Dodson M, Rojo de la Vega EM, Ning Y, Zhang Z, Yao M, Zhang DD, Xu C, Yi X.

Mol Carcinog. 2017 Jun;56(6):1543-1553. doi: 10.1002/mc.22615. Epub 2017 May 2.


Overexpression of HIPK2 circumvents the blockade of apoptosis in chemoresistant ovarian cancer cells.

Puca R, Nardinocchi L, Pistritto G, D'Orazi G.

Gynecol Oncol. 2008 Jun;109(3):403-10. doi: 10.1016/j.ygyno.2008.02.018. Epub 2008 Apr 18.


ARHI (DIRAS3)-mediated autophagy-associated cell death enhances chemosensitivity to cisplatin in ovarian cancer cell lines and xenografts.

Washington MN, Suh G, Orozco AF, Sutton MN, Yang H, Wang Y, Mao W, Millward S, Ornelas A, Atkinson N, Liao W, Bast RC Jr, Lu Z.

Cell Death Dis. 2015 Aug 6;6:e1836. doi: 10.1038/cddis.2015.208.


Time-dependent changes in factors involved in the apoptotic process in human ovarian cancer cells as a response to cisplatin.

Kolfschoten GM, Hulscher TM, Schrier SM, van Houten VM, Pinedo HM, Boven E.

Gynecol Oncol. 2002 Mar;84(3):404-12.


Ionizing radiation but not anticancer drugs causes cell cycle arrest and failure to activate the mitochondrial death pathway in MCF-7 breast carcinoma cells.

Jänicke RU, Engels IH, Dunkern T, Kaina B, Schulze-Osthoff K, Porter AG.

Oncogene. 2001 Aug 16;20(36):5043-53.


Cleavage of the actin-capping protein alpha -adducin at Asp-Asp-Ser-Asp633-Ala by caspase-3 is preceded by its phosphorylation on serine 726 in cisplatin-induced apoptosis of renal epithelial cells.

van de Water B, Tijdens IB, Verbrugge A, Huigsloot M, Dihal AA, Stevens JL, Jaken S, Mulder GJ.

J Biol Chem. 2000 Aug 18;275(33):25805-13.


Proapoptotic protein Smac mediates apoptosis in cisplatin-resistant ovarian cancer cells when treated with the anti-tumor agent AT101.

Hu W, Wang F, Tang J, Liu X, Yuan Z, Nie C, Wei Y.

J Biol Chem. 2012 Jan 2;287(1):68-80. doi: 10.1074/jbc.M111.271205. Epub 2011 Nov 3.


Mechanism of caspase-2 activation upon DNA damage.

Aksenova VI, Kopeina GS, Zamaraev AV, Zhivotovsky BD, Lavrik IN.

Dokl Biochem Biophys. 2016 Mar;467(1):132-5. doi: 10.1134/S1607672916020150. Epub 2016 May 20.


[Effect of MTRR gene on apoptosis and autophagy pathways in multiresistant epithelial ovarian cancer].

Chen J, Wang Q, Zhang W, Li L.

Zhonghua Fu Chan Ke Za Zhi. 2016 Apr 25;51(4):285-92. doi: 10.3760/cma.j.issn.0529-567X.2016.04.008. Chinese.


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