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Items: 1 to 20 of 171

1.

Large scale meta-analyses of fasting plasma glucose raising variants in GCK, GCKR, MTNR1B and G6PC2 and their impacts on type 2 diabetes mellitus risk.

Wang H, Liu L, Zhao J, Cui G, Chen C, Ding H, Wang DW.

PLoS One. 2013 Jun 28;8(6):e67665. doi: 10.1371/journal.pone.0067665. Print 2013.

2.

Effects of GCK, GCKR, G6PC2 and MTNR1B variants on glucose metabolism and insulin secretion.

Hu C, Zhang R, Wang C, Yu W, Lu J, Ma X, Wang J, Jiang F, Tang S, Bao Y, Xiang K, Jia W.

PLoS One. 2010 Jul 23;5(7):e11761. doi: 10.1371/journal.pone.0011761.

3.

Common polymorphisms in MTNR1B, G6PC2 and GCK are associated with increased fasting plasma glucose and impaired beta-cell function in Chinese subjects.

Tam CH, Ho JS, Wang Y, Lee HM, Lam VK, Germer S, Martin M, So WY, Ma RC, Chan JC, Ng MC.

PLoS One. 2010 Jul 8;5(7):e11428. doi: 10.1371/journal.pone.0011428.

4.

Common variants at the GCK, GCKR, G6PC2-ABCB11 and MTNR1B loci are associated with fasting glucose in two Asian populations.

Takeuchi F, Katsuya T, Chakrewarthy S, Yamamoto K, Fujioka A, Serizawa M, Fujisawa T, Nakashima E, Ohnaka K, Ikegami H, Sugiyama T, Nabika T, Kasturiratne A, Yamaguchi S, Kono S, Takayanagi R, Yamori Y, Kobayashi S, Ogihara T, de Silva A, Wickremasinghe R, Kato N.

Diabetologia. 2010 Feb;53(2):299-308. doi: 10.1007/s00125-009-1595-1. Epub 2009 Nov 25.

PMID:
19937311
5.

Common genetic determinants of glucose homeostasis in healthy children: the European Youth Heart Study.

Kelliny C, Ekelund U, Andersen LB, Brage S, Loos RJ, Wareham NJ, Langenberg C.

Diabetes. 2009 Dec;58(12):2939-45. doi: 10.2337/db09-0374. Epub 2009 Sep 9.

6.

Polymorphisms in Four Genes (KCNQ1 rs151290, KLF14 rs972283, GCKR rs780094 and MTNR1B rs10830963) and Their Correlation with Type 2 Diabetes Mellitus in Han Chinese in Henan Province, China.

Gao K, Wang J, Li L, Zhai Y, Ren Y, You H, Wang B, Wu X, Li J, Liu Z, Li X, Huang Y, Luo XP, Hu D, Ohno K, Wang C.

Int J Environ Res Public Health. 2016 Feb 26;13(3). pii: E260. doi: 10.3390/ijerph13030260.

7.

Common genetic variation near melatonin receptor MTNR1B contributes to raised plasma glucose and increased risk of type 2 diabetes among Indian Asians and European Caucasians.

Chambers JC, Zhang W, Zabaneh D, Sehmi J, Jain P, McCarthy MI, Froguel P, Ruokonen A, Balding D, Jarvelin MR, Scott J, Elliott P, Kooner JS.

Diabetes. 2009 Nov;58(11):2703-8. doi: 10.2337/db08-1805. Epub 2009 Aug 3.

8.

Combined effects of single-nucleotide polymorphisms in GCK, GCKR, G6PC2 and MTNR1B on fasting plasma glucose and type 2 diabetes risk.

Reiling E, van 't Riet E, Groenewoud MJ, Welschen LM, van Hove EC, Nijpels G, Maassen JA, Dekker JM, 't Hart LM.

Diabetologia. 2009 Sep;52(9):1866-70. doi: 10.1007/s00125-009-1413-9. Epub 2009 Jun 17.

9.

Association of GCKR rs780094, alone or in combination with GCK rs1799884, with type 2 diabetes and related traits in a Han Chinese population.

Qi Q, Wu Y, Li H, Loos RJ, Hu FB, Sun L, Lu L, Pan A, Liu C, Wu H, Chen L, Yu Z, Lin X.

Diabetologia. 2009 May;52(5):834-43. doi: 10.1007/s00125-009-1290-2. Epub 2009 Feb 25.

PMID:
19241058
10.

The GCKR rs780094 polymorphism is associated with susceptibility of type 2 diabetes, reduced fasting plasma glucose levels, increased triglycerides levels and lower HOMA-IR in Japanese population.

Onuma H, Tabara Y, Kawamoto R, Shimizu I, Kawamura R, Takata Y, Nishida W, Ohashi J, Miki T, Kohara K, Makino H, Osawa H.

J Hum Genet. 2010 Sep;55(9):600-4. doi: 10.1038/jhg.2010.75. Epub 2010 Jun 24.

PMID:
20574426
11.

Effects of 16 genetic variants on fasting glucose and type 2 diabetes in South Asians: ADCY5 and GLIS3 variants may predispose to type 2 diabetes.

Rees SD, Hydrie MZ, O'Hare JP, Kumar S, Shera AS, Basit A, Barnett AH, Kelly MA.

PLoS One. 2011;6(9):e24710. doi: 10.1371/journal.pone.0024710. Epub 2011 Sep 20.

12.

Association of glucokinase regulatory protein polymorphism with type 2 diabetes and fasting plasma glucose: a meta-analysis.

Li H, Xu R, Peng X, Wang Y, Wang T.

Mol Biol Rep. 2013 Jun;40(6):3935-42. doi: 10.1007/s11033-012-2470-6. Epub 2013 Jan 10.

PMID:
23307301
13.

Association between the melatonin receptor 1B gene polymorphism on the risk of type 2 diabetes, impaired glucose regulation: a meta-analysis.

Xia Q, Chen ZX, Wang YC, Ma YS, Zhang F, Che W, Fu D, Wang XF.

PLoS One. 2012;7(11):e50107. doi: 10.1371/journal.pone.0050107. Epub 2012 Nov 30.

14.

HbA1c-based diabetes diagnosis among patients with glucokinase mutation (GCK-MODY) is affected by a genetic variant of glucose-6-phosphatase (G6PC2).

Borowiec M, Fendler W, Dusatkova P, Antosik K, Pruhova S, Cinek O, Mysliwiec M, Jarosz-Chobot P, Malecki MT, Mlynarski W.

Diabet Med. 2012 Nov;29(11):1465-9. doi: 10.1111/j.1464-5491.2012.03671.x.

PMID:
22486180
15.

Association of risk variants for type 2 diabetes and hyperglycemia with gestational diabetes.

Huopio H, Cederberg H, Vangipurapu J, Hakkarainen H, Pääkkönen M, Kuulasmaa T, Heinonen S, Laakso M.

Eur J Endocrinol. 2013 Jul 29;169(3):291-7. doi: 10.1530/EJE-13-0286. Print 2013 Sep.

16.

Common variant in the glucokinase regulatory gene rs780094 and risk of nonalcoholic fatty liver disease: a meta-analysis.

Zain SM, Mohamed Z, Mohamed R.

J Gastroenterol Hepatol. 2015 Jan;30(1):21-7. doi: 10.1111/jgh.12714.

PMID:
25167786
17.

Two susceptible diabetogenic variants near/in MTNR1B are associated with fasting plasma glucose in a Han Chinese cohort.

Kan MY, Zhou DZ, Zhang D, Zhang Z, Chen Z, Yang YF, Guo XZ, Xu H, He L, Liu Y.

Diabet Med. 2010 May;27(5):598-602. doi: 10.1111/j.1464-5491.2010.02975.x.

PMID:
20536959
18.

Interaction effect of genetic polymorphisms in glucokinase (GCK) and glucokinase regulatory protein (GCKR) on metabolic traits in healthy Chinese adults and adolescents.

Tam CH, Ma RC, So WY, Wang Y, Lam VK, Germer S, Martin M, Chan JC, Ng MC.

Diabetes. 2009 Mar;58(3):765-9. doi: 10.2337/db08-1277. Epub 2008 Dec 10.

19.

Association between glucose transporter 1 rs841853 polymorphism and type 2 diabetes mellitus risk may be population specific (1rs8418532).

Du B, Liu S, Cui C, Wang S, Cui W.

J Diabetes. 2013 Sep;5(3):291-9. doi: 10.1111/1753-0407.12042. Epub 2013 May 29.

PMID:
23480298
20.

Associations of common polymorphisms in GCKR with type 2 diabetes and related traits in a Han Chinese population: a case-control study.

Ling Y, Li X, Gu Q, Chen H, Lu D, Gao X.

BMC Med Genet. 2011 May 13;12:66. doi: 10.1186/1471-2350-12-66.

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