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Items: 1 to 20 of 215

1.

A2E induces IL-1ß production in retinal pigment epithelial cells via the NLRP3 inflammasome.

Anderson OA, Finkelstein A, Shima DT.

PLoS One. 2013 Jun 28;8(6):e67263. doi: 10.1371/journal.pone.0067263. Print 2013.

2.

NLRP3 inflammasome activation in retinal pigment epithelial cells by lysosomal destabilization: implications for age-related macular degeneration.

Tseng WA, Thein T, Kinnunen K, Lashkari K, Gregory MS, D'Amore PA, Ksander BR.

Invest Ophthalmol Vis Sci. 2013 Jan 7;54(1):110-20. doi: 10.1167/iovs.12-10655.

3.

Interleukin-17A Induces IL-1β Secretion From RPE Cells Via the NLRP3 Inflammasome.

Zhang S, Yu N, Zhang R, Zhang S, Wu J.

Invest Ophthalmol Vis Sci. 2016 Feb;57(2):312-9. doi: 10.1167/iovs.15-17578.

PMID:
26830368
4.

Complement Component C5a Primes Retinal Pigment Epithelial Cells for Inflammasome Activation by Lipofuscin-mediated Photooxidative Damage.

Brandstetter C, Holz FG, Krohne TU.

J Biol Chem. 2015 Dec 25;290(52):31189-98. doi: 10.1074/jbc.M115.671180. Epub 2015 Nov 12.

5.

Vinpocetine inhibits amyloid-beta induced activation of NF-κB, NLRP3 inflammasome and cytokine production in retinal pigment epithelial cells.

Liu RT, Wang A, To E, Gao J, Cao S, Cui JZ, Matsubara JA.

Exp Eye Res. 2014 Oct;127:49-58. doi: 10.1016/j.exer.2014.07.003. Epub 2014 Jul 17.

6.

NLRP3 Upregulation in Retinal Pigment Epithelium in Age-Related Macular Degeneration.

Wang Y, Hanus JW, Abu-Asab MS, Shen D, Ogilvy A, Ou J, Chu XK, Shi G, Li W, Wang S, Chan CC.

Int J Mol Sci. 2016 Jan 8;17(1). pii: E73. doi: 10.3390/ijms17010073.

7.

Light induces NLRP3 inflammasome activation in retinal pigment epithelial cells via lipofuscin-mediated photooxidative damage.

Brandstetter C, Mohr LK, Latz E, Holz FG, Krohne TU.

J Mol Med (Berl). 2015 Aug;93(8):905-16. doi: 10.1007/s00109-015-1275-1. Epub 2015 Mar 18.

8.

Reactive oxygen species activated NLRP3 inflammasomes initiate inflammation in hyperosmolarity stressed human corneal epithelial cells and environment-induced dry eye patients.

Zheng Q, Ren Y, Reinach PS, Xiao B, Lu H, Zhu Y, Qu J, Chen W.

Exp Eye Res. 2015 May;134:133-40. doi: 10.1016/j.exer.2015.02.013. Epub 2015 Feb 18.

PMID:
25701684
9.

P2Y1 Receptor Signaling Contributes to High Salt-Induced Priming of the NLRP3 Inflammasome in Retinal Pigment Epithelial Cells.

Prager P, Hollborn M, Steffen A, Wiedemann P, Kohen L, Bringmann A.

PLoS One. 2016 Oct 27;11(10):e0165653. doi: 10.1371/journal.pone.0165653. eCollection 2016.

10.

Suppression of ribosomal function triggers innate immune signaling through activation of the NLRP3 inflammasome.

Vyleta ML, Wong J, Magun BE.

PLoS One. 2012;7(5):e36044. doi: 10.1371/journal.pone.0036044. Epub 2012 May 14.

11.

Trichomonas vaginalis induces IL-1β production in a human prostate epithelial cell line by activating the NLRP3 inflammasome via reactive oxygen species and potassium ion efflux.

Gu NY, Kim JH, Han IH, Im SJ, Seo MY, Chung YH, Ryu JS.

Prostate. 2016 Jul;76(10):885-96. doi: 10.1002/pros.23178. Epub 2016 Mar 9.

PMID:
26959386
12.

Serum amyloid A activates the NLRP3 inflammasome via P2X7 receptor and a cathepsin B-sensitive pathway.

Niemi K, Teirilä L, Lappalainen J, Rajamäki K, Baumann MH, Öörni K, Wolff H, Kovanen PT, Matikainen S, Eklund KK.

J Immunol. 2011 Jun 1;186(11):6119-28. doi: 10.4049/jimmunol.1002843. Epub 2011 Apr 20.

13.

Protective effect of autophagy on human retinal pigment epithelial cells against lipofuscin fluorophore A2E: implications for age-related macular degeneration.

Zhang J, Bai Y, Huang L, Qi Y, Zhang Q, Li S, Wu Y, Li X.

Cell Death Dis. 2015 Nov 12;6:e1972. doi: 10.1038/cddis.2015.330.

14.

Aloe vera downregulates LPS-induced inflammatory cytokine production and expression of NLRP3 inflammasome in human macrophages.

Budai MM, Varga A, Milesz S, Tőzsér J, Benkő S.

Mol Immunol. 2013 Dec;56(4):471-9. doi: 10.1016/j.molimm.2013.05.005. Epub 2013 Aug 1.

PMID:
23911403
15.

Alcohol-induced IL-1β in the brain is mediated by NLRP3/ASC inflammasome activation that amplifies neuroinflammation.

Lippai D, Bala S, Petrasek J, Csak T, Levin I, Kurt-Jones EA, Szabo G.

J Leukoc Biol. 2013 Jul;94(1):171-82. doi: 10.1189/jlb.1212659. Epub 2013 Apr 26.

16.

Lipopolysaccharide/adenosine triphosphate induces IL‑1β and IL-18 secretion through the NLRP3 inflammasome in RAW264.7 murine macrophage cells.

Xie Q, Shen WW, Zhong J, Huang C, Zhang L, Li J.

Int J Mol Med. 2014 Jul;34(1):341-9. doi: 10.3892/ijmm.2014.1755. Epub 2014 Apr 24.

PMID:
24789624
17.

TLR agonists stimulate Nlrp3-dependent IL-1β production independently of the purinergic P2X7 receptor in dendritic cells and in vivo.

He Y, Franchi L, Núñez G.

J Immunol. 2013 Jan 1;190(1):334-9. doi: 10.4049/jimmunol.1202737. Epub 2012 Dec 7.

19.

VEGF-A and the NLRP3 Inflammasome in Age-Related Macular Degeneration.

Marneros AG.

Adv Exp Med Biol. 2016;854:79-85. doi: 10.1007/978-3-319-17121-0_12.

PMID:
26427397
20.

NLRP3 inflammasome: activation and regulation in age-related macular degeneration.

Gao J, Liu RT, Cao S, Cui JZ, Wang A, To E, Matsubara JA.

Mediators Inflamm. 2015;2015:690243. doi: 10.1155/2015/690243. Epub 2015 Jan 27. Review.

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