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Items: 1 to 20 of 96

1.

HSP90 Inhibitors, Geldanamycin and Radicicol, Enhance Fisetin-Induced Cytotoxicity via Induction of Apoptosis in Human Colonic Cancer Cells.

Wu MS, Lien GS, Shen SC, Yang LY, Chen YC.

Evid Based Complement Alternat Med. 2013;2013:987612. doi: 10.1155/2013/987612. Epub 2013 Jun 11.

2.

N-acetyl-L-cysteine enhances fisetin-induced cytotoxicity via induction of ROS-independent apoptosis in human colonic cancer cells.

Wu MS, Lien GS, Shen SC, Yang LY, Chen YC.

Mol Carcinog. 2014 Feb;53 Suppl 1:E119-29. doi: 10.1002/mc.22053. Epub 2013 Sep 9.

PMID:
24019108
3.

Induction of p53 contributes to apoptosis of HCT-116 human colon cancer cells induced by the dietary compound fisetin.

Lim DY, Park JH.

Am J Physiol Gastrointest Liver Physiol. 2009 May;296(5):G1060-8. doi: 10.1152/ajpgi.90490.2008. Epub 2009 Mar 5.

4.

Heat shock protein inhibitors increase the efficacy of measles virotherapy.

Liu C, Erlichman C, McDonald CJ, Ingle JN, Zollman P, Iankov I, Russell SJ, Galanis E.

Gene Ther. 2008 Jul;15(14):1024-34. doi: 10.1038/gt.2008.30. Epub 2008 Mar 20.

5.
6.

Inhibition of HSP90-dependent telomerase activity in amyloid β-induced apoptosis of cerebral endothelial cells.

Chiu WT, Shen SC, Yang LY, Chow JM, Wu CY, Chen YC.

J Cell Physiol. 2011 Aug;226(8):2041-51. doi: 10.1002/jcp.22536.

PMID:
21520056
8.

Radicicol, an inhibitor of Hsp90, enhances TRAIL-induced apoptosis in human epithelial ovarian carcinoma cells by promoting activation of apoptosis-related proteins.

Kim YJ, Lee SA, Myung SC, Kim W, Lee CS.

Mol Cell Biochem. 2012 Jan;359(1-2):33-43. doi: 10.1007/s11010-011-0997-9. Epub 2011 Jul 29.

PMID:
21800052
9.

Involvement of human heat shock protein 90 alpha in nicotine-induced apoptosis.

Wu YP, Kita K, Suzuki N.

Int J Cancer. 2002 Jul 1;100(1):37-42.

10.

Heat shock protein 90 and tyrosine kinase regulate eNOS NO* generation but not NO* bioactivity.

Ou J, Fontana JT, Ou Z, Jones DW, Ackerman AW, Oldham KT, Yu J, Sessa WC, Pritchard KA Jr.

Am J Physiol Heart Circ Physiol. 2004 Feb;286(2):H561-9. Epub 2003 Oct 9.

11.

Wogonin and fisetin induction of apoptosis through activation of caspase 3 cascade and alternative expression of p21 protein in hepatocellular carcinoma cells SK-HEP-1.

Chen YC, Shen SC, Lee WR, Lin HY, Ko CH, Shih CM, Yang LL.

Arch Toxicol. 2002 Jun;76(5-6):351-9. Epub 2002 Apr 23.

PMID:
12107653
12.

Flavone inhibition of tumor growth via apoptosis in vitro and in vivo.

Chen YC, Shen SC, Chow JM, Ko CH, Tseng SW.

Int J Oncol. 2004 Sep;25(3):661-70.

PMID:
15289867
13.

18β-glycyrrhetinic acid potentiates Hsp90 inhibition-induced apoptosis in human epithelial ovarian carcinoma cells via activation of death receptor and mitochondrial pathway.

Yang JC, Myung SC, Kim W, Lee CS.

Mol Cell Biochem. 2012 Nov;370(1-2):209-19. doi: 10.1007/s11010-012-1412-x. Epub 2012 Aug 4.

PMID:
22865487
14.

Targeting PI3K/Akt/HSP90 signaling sensitizes gastric cancer cells to deoxycholate-induced apoptosis.

Redlak MJ, Miller TA.

Dig Dis Sci. 2011 Feb;56(2):323-9. doi: 10.1007/s10620-010-1294-2. Epub 2010 Jun 29.

PMID:
20585984
15.

Combined effect of Hsp90 inhibitor geldanamycin and parthenolide via reactive oxygen species-mediated apoptotic process on epithelial ovarian cancer cells.

Lee CS, Kim YJ, Lee SA, Myung SC, Kim W.

Basic Clin Pharmacol Toxicol. 2012 Sep;111(3):173-81. doi: 10.1111/j.1742-7843.2012.00883.x. Epub 2012 Apr 16.

16.

Bioflavonoid Fisetin Loaded α-Tocopherol-Poly(lactic acid)-Based Polymeric Micelles for Enhanced Anticancer Efficacy in Breast Cancers.

Wang L, Zhang DZ, Wang YX.

Pharm Res. 2017 Feb;34(2):453-461. doi: 10.1007/s11095-016-2077-z. Epub 2016 Dec 21.

PMID:
28004315
17.

Geldanamycin and its analog induce cytotoxicity in cultured human retinal pigment epithelial cells.

Wu WC, Wu MH, Chang YC, Hsieh MC, Wu HJ, Cheng KC, Lai YH, Kao YH.

Exp Eye Res. 2010 Aug;91(2):211-9. doi: 10.1016/j.exer.2010.05.005. Epub 2010 May 20.

PMID:
20493187
18.

The effects of heat shock protein 90 inhibitors on apoptosis and viral replication in primary effusion lymphoma cells.

Higashi C, Saji C, Yamada K, Kagawa H, Ohga R, Taira T, Fujimuro M.

Biol Pharm Bull. 2012;35(5):725-30.

19.

Radicicol but not geldanamycin evokes oxidative stress response and efflux protein inhibition in ARPE-19 human retinal pigment epithelial cells.

Ryhänen T, Mannermaa E, Oksala N, Viiri J, Paimela T, Salminen A, Atalay M, Kaarniranta K.

Eur J Pharmacol. 2008 Apr 28;584(2-3):229-36. doi: 10.1016/j.ejphar.2008.02.010. Epub 2008 Feb 14.

PMID:
18313664
20.

Geldanamycin, an inhibitor of Hsp90, potentiates cytochrome P4502E1-mediated toxicity in HepG2 cells.

Dey A, Cederbaum AI.

J Pharmacol Exp Ther. 2006 Jun;317(3):1391-9. Epub 2006 Mar 2.

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