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Items: 1 to 20 of 72

1.

Ionizing radiation enhances dl922-947-mediated cell death of anaplastic thyroid carcinoma cells.

Passaro C, Abagnale A, Libertini S, Volpe M, Botta G, Cella L, Pacelli R, Halldèn G, Gillespie D, Portella G.

Endocr Relat Cancer. 2013 Aug 19;20(5):633-47. doi: 10.1530/ERC-13-0001. Print 2013 Oct.

2.

Bevacizumab increases viral distribution in human anaplastic thyroid carcinoma xenografts and enhances the effects of E1A-defective adenovirus dl922-947.

Libertini S, Iacuzzo I, Perruolo G, Scala S, Ieranò C, Franco R, Hallden G, Portella G.

Clin Cancer Res. 2008 Oct 15;14(20):6505-14. doi: 10.1158/1078-0432.CCR-08-0200.

3.

AZD1152 negatively affects the growth of anaplastic thyroid carcinoma cells and enhances the effects of oncolytic virus dl922-947.

Libertini S, Abagnale A, Passaro C, Botta G, Barbato S, Chieffi P, Portella G.

Endocr Relat Cancer. 2011 Jan 13;18(1):129-41. doi: 10.1677/ERC-10-0234. Print 2011 Feb.

4.

PARP inhibitor olaparib increases the oncolytic activity of dl922-947 in in vitro and in vivo model of anaplastic thyroid carcinoma.

Passaro C, Volpe M, Botta G, Scamardella E, Perruolo G, Gillespie D, Libertini S, Portella G.

Mol Oncol. 2015 Jan;9(1):78-92. doi: 10.1016/j.molonc.2014.07.022. Epub 2014 Aug 2.

5.

The oncolytic virus dl922-947 reduces IL-8/CXCL8 and MCP-1/CCL2 expression and impairs angiogenesis and macrophage infiltration in anaplastic thyroid carcinoma.

Passaro C, Borriello F, Vastolo V, Di Somma S, Scamardella E, Gigantino V, Franco R, Marone G, Portella G.

Oncotarget. 2016 Jan 12;7(2):1500-15. doi: 10.18632/oncotarget.6430.

6.

Lovastatin enhances the replication of the oncolytic adenovirus dl1520 and its antineoplastic activity against anaplastic thyroid carcinoma cells.

Libertini S, Iacuzzo I, Ferraro A, Vitale M, Bifulco M, Fusco A, Portella G.

Endocrinology. 2007 Nov;148(11):5186-94. Epub 2007 Aug 9.

PMID:
17690162
7.

Telomerase-dependent oncolytic adenovirus sensitizes human cancer cells to ionizing radiation via inhibition of DNA repair machinery.

Kuroda S, Fujiwara T, Shirakawa Y, Yamasaki Y, Yano S, Uno F, Tazawa H, Hashimoto Y, Watanabe Y, Noma K, Urata Y, Kagawa S, Fujiwara T.

Cancer Res. 2010 Nov 15;70(22):9339-48. doi: 10.1158/0008-5472.CAN-10-2333. Epub 2010 Nov 2.

8.

ONYX-411, a conditionally replicative oncolytic adenovirus, induces cell death in anaplastic thyroid carcinoma cell lines and suppresses the growth of xenograft tumors in nude mice.

Reddi HV, Madde P, Reichert-Eberhardt AJ, Galanis EC, Copland JA, McIver B, Grebe SK, Eberhardt NL.

Cancer Gene Ther. 2008 Nov;15(11):750-7. doi: 10.1038/cgt.2008.44. Epub 2008 Jun 27.

9.

Mre11 inhibition by oncolytic adenovirus associates with autophagy and underlies synergy with ionizing radiation.

Rajecki M, af Hällström T, Hakkarainen T, Nokisalmi P, Hautaniemi S, Nieminen AI, Tenhunen M, Rantanen V, Desmond RA, Chen DT, Guse K, Stenman UH, Gargini R, Kapanen M, Klefström J, Kanerva A, Pesonen S, Ahtiainen L, Hemminki A.

Int J Cancer. 2009 Nov 15;125(10):2441-9. doi: 10.1002/ijc.24608.

10.

Genomic DNA damage and ATR-Chk1 signaling determine oncolytic adenoviral efficacy in human ovarian cancer cells.

Connell CM, Shibata A, Tookman LA, Archibald KM, Flak MB, Pirlo KJ, Lockley M, Wheatley SP, McNeish IA.

J Clin Invest. 2011 Apr;121(4):1283-97. doi: 10.1172/JCI43976. Epub 2011 Mar 7.

11.

The control of anaplastic thyroid carcinoma cell lines by oncolytic poxviruses.

Mundi N, Um S, Yoo J, Rizzo G, Black M, Pinto N, Palma DA, Fung K, MacNeil D, Mymryk JS, Barrett JW, Nichols AC.

Virus Res. 2014 Sep 22;190:53-9. doi: 10.1016/j.virusres.2014.07.009. Epub 2014 Jul 16.

PMID:
25038405
12.

An oncolytic adenovirus defective in pRb-binding (dl922-947) can efficiently eliminate pancreatic cancer cells and tumors in vivo in combination with 5-FU or gemcitabine.

Bhattacharyya M, Francis J, Eddouadi A, Lemoine NR, Halldén G.

Cancer Gene Ther. 2011 Oct;18(10):734-43. doi: 10.1038/cgt.2011.45. Epub 2011 Aug 12.

PMID:
21836633
13.

Inhibition of autophagy enhances the effects of E1A-defective oncolytic adenovirus dl922-947 against glioma cells in vitro and in vivo.

Botta G, Passaro C, Libertini S, Abagnale A, Barbato S, Maione AS, Hallden G, Beguinot F, Formisano P, Portella G.

Hum Gene Ther. 2012 Jun;23(6):623-34. doi: 10.1089/hum.2011.120. Epub 2012 Jun 5.

PMID:
22475378
14.

Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks.

Takemura H, Rao VA, Sordet O, Furuta T, Miao ZH, Meng L, Zhang H, Pommier Y.

J Biol Chem. 2006 Oct 13;281(41):30814-23. Epub 2006 Aug 10.

15.

Comparison of molecular strategies for breast cancer virotherapy using oncolytic adenovirus.

Bazan-Peregrino M, Carlisle RC, Hernandez-Alcoceba R, Iggo R, Homicsko K, Fisher KD, Halldén G, Mautner V, Shen Y, Seymour LW.

Hum Gene Ther. 2008 Sep;19(9):873-86. doi: 10.1089/hum.2008.047.

PMID:
18710328
16.

Synergy of a herpes oncolytic virus and paclitaxel for anaplastic thyroid cancer.

Lin SF, Gao SP, Price DL, Li S, Chou TC, Singh P, Huang YY, Fong Y, Wong RJ.

Clin Cancer Res. 2008 Mar 1;14(5):1519-28. doi: 10.1158/1078-0432.CCR-07-4628.

17.

Intratumoral coadministration of hyaluronidase enzyme and oncolytic adenoviruses enhances virus potency in metastatic tumor models.

Ganesh S, Gonzalez-Edick M, Gibbons D, Van Roey M, Jooss K.

Clin Cancer Res. 2008 Jun 15;14(12):3933-41. doi: 10.1158/1078-0432.CCR-07-4732.

18.

Treatment of cholangiocarcinoma with oncolytic herpes simplex virus combined with external beam radiation therapy.

Jarnagin WR, Zager JS, Hezel M, Stanziale SF, Adusumilli PS, Gonen M, Ebright MI, Culliford A, Gusani NJ, Fong Y.

Cancer Gene Ther. 2006 Mar;13(3):326-34.

PMID:
16138120
19.

HSF1 overexpression enhances oncolytic effect of replicative adenovirus.

Wang C, Dai Z, Fan R, Deng Y, Lv G, Lu G.

J Transl Med. 2010 May 6;8:44. doi: 10.1186/1479-5876-8-44.

20.

Reexpression of human somatostatin receptor gene 2 gene mediated by oncolytic adenovirus increases antitumor activity of tumor necrosis factor-related apoptosis-inducing ligand against pancreatic cancer.

Zhang Z, Huang Y, Newman K, Gu J, Zhang X, Wu H, Zhao M, Xianyu Z, Liu X.

Clin Cancer Res. 2009 Aug 15;15(16):5154-60. doi: 10.1158/1078-0432.CCR-09-0025. Epub 2009 Aug 11.

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