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Items: 1 to 20 of 60

1.

Regulation of cell proliferation and migration by keratin19-induced nuclear import of early growth response-1 in breast cancer cells.

Ju JH, Yang W, Lee KM, Oh S, Nam K, Shim S, Shin SY, Gye MC, Chu IS, Shin I.

Clin Cancer Res. 2013 Aug 15;19(16):4335-46. doi: 10.1158/1078-0432.CCR-12-3295. Epub 2013 Jul 5.

2.

Cytokeratin19 induced by HER2/ERK binds and stabilizes HER2 on cell membranes.

Ju JH, Oh S, Lee KM, Yang W, Nam KS, Moon HG, Noh DY, Kim CG, Park G, Park JB, Lee T, Arteaga CL, Shin I.

Cell Death Differ. 2015 Apr;22(4):665-76. doi: 10.1038/cdd.2014.155. Epub 2014 Oct 24.

3.

Acid ceramidase promotes nuclear export of PTEN through sphingosine 1-phosphate mediated Akt signaling.

Beckham TH, Cheng JC, Lu P, Marrison ST, Norris JS, Liu X.

PLoS One. 2013 Oct 1;8(10):e76593. doi: 10.1371/journal.pone.0076593. eCollection 2013.

4.

Crucial role for early growth response-1 in the transcriptional regulation of miR-20b in breast cancer.

Li D, Ilnytskyy Y, Kovalchuk A, Khachigian LM, Bronson RT, Wang B, Kovalchuk O.

Oncotarget. 2013 Sep;4(9):1373-87.

5.

MicroRNA miR-183 functions as an oncogene by targeting the transcription factor EGR1 and promoting tumor cell migration.

Sarver AL, Li L, Subramanian S.

Cancer Res. 2010 Dec 1;70(23):9570-80. doi: 10.1158/0008-5472.CAN-10-2074. Epub 2010 Nov 30.

6.

Nestin positively regulates the Wnt/β-catenin pathway and the proliferation, survival and invasiveness of breast cancer stem cells.

Zhao Z, Lu P, Zhang H, Xu H, Gao N, Li M, Liu C.

Breast Cancer Res. 2014 Jul 24;16(4):408. doi: 10.1186/s13058-014-0408-8.

7.

Early growth response protein 1 upregulation and nuclear translocation by 2'-benzoyloxycinnamaldehyde induces prostate cancer cell death.

Kang HS, Ock J, Lee HJ, Lee YJ, Kwon BM, Hong SH.

Cancer Lett. 2013 Feb 28;329(2):217-27. doi: 10.1016/j.canlet.2012.11.006. Epub 2012 Nov 23.

PMID:
23178451
8.

Alterations of EGFR, p53 and PTEN that mimic changes found in basal-like breast cancer promote transformation of human mammary epithelial cells.

Pires MM, Hopkins BD, Saal LH, Parsons RE.

Cancer Biol Ther. 2013 Mar;14(3):246-53. doi: 10.4161/cbt.23297. Epub 2013 Jan 4.

9.

GATA2 negatively regulates PTEN by preventing nuclear translocation of androgen receptor and by androgen-independent suppression of PTEN transcription in breast cancer.

Wang Y, He X, Ngeow J, Eng C.

Hum Mol Genet. 2012 Feb 1;21(3):569-76. doi: 10.1093/hmg/ddr491. Epub 2011 Oct 21.

PMID:
22021428
10.

microRNA-133a regulates the cell cycle and proliferation of breast cancer cells by targeting epidermal growth factor receptor through the EGFR/Akt signaling pathway.

Cui W, Zhang S, Shan C, Zhou L, Zhou Z.

FEBS J. 2013 Aug;280(16):3962-74. doi: 10.1111/febs.12398. Epub 2013 Jul 10.

11.

Grb7 upregulation is a molecular adaptation to HER2 signaling inhibition due to removal of Akt-mediated gene repression.

Nencioni A, Cea M, Garuti A, Passalacqua M, Raffaghello L, Soncini D, Moran E, Zoppoli G, Pistoia V, Patrone F, Ballestrero A.

PLoS One. 2010 Feb 2;5(2):e9024. doi: 10.1371/journal.pone.0009024.

12.

The nuclear localization signal is required for nuclear GPER translocation and function in breast Cancer-Associated Fibroblasts (CAFs).

Pupo M, Vivacqua A, Perrotta I, Pisano A, Aquila S, Abonante S, Gasperi-Campani A, Pezzi V, Maggiolini M.

Mol Cell Endocrinol. 2013 Aug 25;376(1-2):23-32. doi: 10.1016/j.mce.2013.05.023. Epub 2013 Jun 5.

PMID:
23748028
13.

EGR1-dependent PTEN upregulation by 2-benzoyloxycinnamaldehyde attenuates cell invasion and EMT in colon cancer.

Kim J, Kang HS, Lee YJ, Lee HJ, Yun J, Shin JH, Lee CW, Kwon BM, Hong SH.

Cancer Lett. 2014 Jul 10;349(1):35-44. doi: 10.1016/j.canlet.2014.03.025. Epub 2014 Apr 1.

PMID:
24704156
14.

Amyloid-β precursor protein promotes cell proliferation and motility of advanced breast cancer.

Lim S, Yoo BK, Kim HS, Gilmore HL, Lee Y, Lee HP, Kim SJ, Letterio J, Lee HG.

BMC Cancer. 2014 Dec 10;14:928. doi: 10.1186/1471-2407-14-928.

15.

Erythropoietin-induced activation of the JAK2/STAT5, PI3K/Akt, and Ras/ERK pathways promotes malignant cell behavior in a modified breast cancer cell line.

Shi Z, Hodges VM, Dunlop EA, Percy MJ, Maxwell AP, El-Tanani M, Lappin TR.

Mol Cancer Res. 2010 Apr;8(4):615-26. doi: 10.1158/1541-7786.MCR-09-0264. Epub 2010 Mar 30.

16.

Silencing of the IKKε gene by siRNA inhibits invasiveness and growth of breast cancer cells.

Qin B, Cheng K.

Breast Cancer Res. 2010;12(5):R74. doi: 10.1186/bcr2644. Epub 2010 Sep 23.

17.

Doxorubicin downregulates cell surface B7-H1 expression and upregulates its nuclear expression in breast cancer cells: role of B7-H1 as an anti-apoptotic molecule.

Ghebeh H, Lehe C, Barhoush E, Al-Romaih K, Tulbah A, Al-Alwan M, Hendrayani SF, Manogaran P, Alaiya A, Al-Tweigeri T, Aboussekhra A, Dermime S.

Breast Cancer Res. 2010;12(4):R48. doi: 10.1186/bcr2605. Epub 2010 Jul 13.

18.

Crk adaptor proteins act as key signaling integrators for breast tumorigenesis.

Fathers KE, Bell ES, Rajadurai CV, Cory S, Zhao H, Mourskaia A, Zuo D, Madore J, Monast A, Mes-Masson AM, Grosset AA, Gaboury L, Hallet M, Siegel P, Park M.

Breast Cancer Res. 2012 May 8;14(3):R74.

19.

RNAi-mediated silencing of VEGF-C inhibits non-small cell lung cancer progression by simultaneously down-regulating the CXCR4, CCR7, VEGFR-2 and VEGFR-3-dependent axes-induced ERK, p38 and AKT signalling pathways.

Feng Y, Hu J, Ma J, Feng K, Zhang X, Yang S, Wang W, Zhang J, Zhang Y.

Eur J Cancer. 2011 Oct;47(15):2353-63. doi: 10.1016/j.ejca.2011.05.006. Epub 2011 Jun 15.

PMID:
21680174
20.

Nuclear and cytoplasmic LIMK1 enhances human breast cancer progression.

McConnell BV, Koto K, Gutierrez-Hartmann A.

Mol Cancer. 2011 Jun 18;10:75. doi: 10.1186/1476-4598-10-75.

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