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Items: 1 to 20 of 175

1.

Influence of chronic hyperglycemia on the loss of the unfolded protein response in transplanted islets.

Walters SN, Luzuriaga J, Chan JY, Grey ST, Laybutt DR.

J Mol Endocrinol. 2013 Sep 6;51(2):225-32. doi: 10.1530/JME-13-0016. Print 2013 Oct.

PMID:
23833251
2.

Influence of diabetes on the loss of beta cell differentiation after islet transplantation in rats.

Laybutt DR, Hawkins YC, Lock J, Lebet J, Sharma A, Bonner-Weir S, Weir GC.

Diabetologia. 2007 Oct;50(10):2117-25. Epub 2007 Jul 20.

PMID:
17641871
3.

Failure of the adaptive unfolded protein response in islets of obese mice is linked with abnormalities in β-cell gene expression and progression to diabetes.

Chan JY, Luzuriaga J, Bensellam M, Biden TJ, Laybutt DR.

Diabetes. 2013 May;62(5):1557-68. doi: 10.2337/db12-0701. Epub 2012 Dec 28.

4.

Role of blood glucose in cytokine gene expression in early syngeneic islet transplantation.

Montolio M, Téllez N, Soler J, Montanya E.

Cell Transplant. 2007;16(5):517-25.

PMID:
17708341
5.
6.

Islet graft response to transplantation injury includes upregulation of protective as well as apoptotic genes.

Rodríguez-Mulero S, Montanya E.

Cell Transplant. 2008;17(9):1025-34.

PMID:
19177839
7.

Evidence of endoplasmic reticulum stress mediating cell death in transplanted human islets.

Negi S, Park SH, Jetha A, Aikin R, Tremblay M, Paraskevas S.

Cell Transplant. 2012;21(5):889-900. doi: 10.3727/096368911X603639. Epub 2011 Dec 13.

PMID:
22182941
8.

Changes in gene expression in beta cells after islet isolation and transplantation using laser-capture microdissection.

Ahn YB, Xu G, Marselli L, Toschi E, Sharma A, Bonner-Weir S, Sgroi DC, Weir GC.

Diabetologia. 2007 Feb;50(2):334-42. Epub 2006 Dec 16.

PMID:
17180350
9.

The balance between adaptive and apoptotic unfolded protein responses regulates β-cell death under ER stress conditions through XBP1, CHOP and JNK.

Chan JY, Luzuriaga J, Maxwell EL, West PK, Bensellam M, Laybutt DR.

Mol Cell Endocrinol. 2015 Sep 15;413:189-201. doi: 10.1016/j.mce.2015.06.025. Epub 2015 Jun 30.

PMID:
26135354
10.

Beta-cell destruction in NOD mice correlates with Fas (CD95) expression on beta-cells and proinflammatory cytokine expression in islets.

Suarez-Pinzon W, Sorensen O, Bleackley RC, Elliott JF, Rajotte RV, Rabinovitch A.

Diabetes. 1999 Jan;48(1):21-8.

PMID:
9892218
11.

Signalling danger: endoplasmic reticulum stress and the unfolded protein response in pancreatic islet inflammation.

Eizirik DL, Miani M, Cardozo AK.

Diabetologia. 2013 Feb;56(2):234-41. doi: 10.1007/s00125-012-2762-3. Epub 2012 Nov 7. Review.

PMID:
23132339
12.

Survival of an islet allograft deficient in iNOS after implantation into diabetic NOD mice.

Börjesson A, Andersson AK, Sandler S.

Cell Transplant. 2006;15(8-9):769-75.

PMID:
17269447
13.

Loss of glucose-induced insulin secretion and GLUT2 expression in transplanted beta-cells.

Ogawa Y, Noma Y, Davalli AM, Wu YJ, Thorens B, Bonner-Weir S, Weir GC.

Diabetes. 1995 Jan;44(1):75-9.

PMID:
7813817
14.

Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia.

Laybutt DR, Sharma A, Sgroi DC, Gaudet J, Bonner-Weir S, Weir GC.

J Biol Chem. 2002 Mar 29;277(13):10912-21. Epub 2002 Jan 8.

15.

Interleukin-1beta and inducible form of nitric oxide synthase expression in early syngeneic islet transplantation.

Montolio M, Biarnés M, Téllez N, Escoriza J, Soler J, Montanya E.

J Endocrinol. 2007 Jan;192(1):169-77.

16.

Aberrant islet unfolded protein response in type 2 diabetes.

Engin F, Nguyen T, Yermalovich A, Hotamisligil GS.

Sci Rep. 2014 Feb 11;4:4054. doi: 10.1038/srep04054.

17.
18.

Beta-cell death and mass in syngeneically transplanted islets exposed to short- and long-term hyperglycemia.

Biarnés M, Montolio M, Nacher V, Raurell M, Soler J, Montanya E.

Diabetes. 2002 Jan;51(1):66-72.

19.

Critical reduction in beta-cell mass results in two distinct outcomes over time. Adaptation with impaired glucose tolerance or decompensated diabetes.

Laybutt DR, Glandt M, Xu G, Ahn YB, Trivedi N, Bonner-Weir S, Weir GC.

J Biol Chem. 2003 Jan 31;278(5):2997-3005. Epub 2002 Nov 15.

20.

Pancreas-Specific Sirt1-Deficiency in Mice Compromises Beta-Cell Function without Development of Hyperglycemia.

Pinho AV, Bensellam M, Wauters E, Rees M, Giry-Laterriere M, Mawson A, Ly le Q, Biankin AV, Wu J, Laybutt DR, Rooman I.

PLoS One. 2015 Jun 5;10(6):e0128012. doi: 10.1371/journal.pone.0128012. eCollection 2015.

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