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Items: 1 to 20 of 82

1.

Facilitates chromatin transcription complex is an "accelerator" of tumor transformation and potential marker and target of aggressive cancers.

Garcia H, Miecznikowski JC, Safina A, Commane M, Ruusulehto A, Kilpinen S, Leach RW, Attwood K, Li Y, Degan S, Omilian AR, Guryanova O, Papantonopoulou O, Wang J, Buck M, Liu S, Morrison C, Gurova KV.

Cell Rep. 2013 Jul 11;4(1):159-73. doi: 10.1016/j.celrep.2013.06.013. Epub 2013 Jul 3.

2.

Expression of FACT in mammalian tissues suggests its role in maintaining of undifferentiated state of cells.

Garcia H, Fleyshman D, Kolesnikova K, Safina A, Commane M, Paszkiewicz G, Omelian A, Morrison C, Gurova K.

Oncotarget. 2011 Oct;2(10):783-96.

3.

Complex mutual regulation of facilitates chromatin transcription (FACT) subunits on both mRNA and protein levels in human cells.

Safina A, Garcia H, Commane M, Guryanova O, Degan S, Kolesnikova K, Gurova KV.

Cell Cycle. 2013 Aug 1;12(15):2423-34. doi: 10.4161/cc.25452. Epub 2013 Jun 28.

4.

Keys to open chromatin for transcription activation: FACT and Asf1.

Krebs A, Tora L.

Mol Cell. 2009 May 14;34(4):397-9. doi: 10.1016/j.molcel.2009.05.004.

5.

Histone chaperone FACT coordinates nucleosome interaction through multiple synergistic binding events.

Winkler DD, Muthurajan UM, Hieb AR, Luger K.

J Biol Chem. 2011 Dec 2;286(48):41883-92. doi: 10.1074/jbc.M111.301465. Epub 2011 Oct 3.

6.

HMG-I/Y, a new c-Myc target gene and potential oncogene.

Wood LJ, Mukherjee M, Dolde CE, Xu Y, Maher JF, Bunton TE, Williams JB, Resar LM.

Mol Cell Biol. 2000 Aug;20(15):5490-502.

7.

FACT and the proteasome promote promoter chromatin disassembly and transcriptional initiation.

Ransom M, Williams SK, Dechassa ML, Das C, Linger J, Adkins M, Liu C, Bartholomew B, Tyler JK.

J Biol Chem. 2009 Aug 28;284(35):23461-71. doi: 10.1074/jbc.M109.019562. Epub 2009 Jul 1.

8.

The histone chaperone facilitates chromatin transcription (FACT) protein maintains normal replication fork rates.

Abe T, Sugimura K, Hosono Y, Takami Y, Akita M, Yoshimura A, Tada S, Nakayama T, Murofushi H, Okumura K, Takeda S, Horikoshi M, Seki M, Enomoto T.

J Biol Chem. 2011 Sep 2;286(35):30504-12. doi: 10.1074/jbc.M111.264721. Epub 2011 Jul 7.

9.

Inhibition of expression of the chromatin remodeling gene, SNF2L, selectively leads to DNA damage, growth inhibition, and cancer cell death.

Ye Y, Xiao Y, Wang W, Wang Q, Yearsley K, Wani AA, Yan Q, Gao JX, Shetuni BS, Barsky SH.

Mol Cancer Res. 2009 Dec;7(12):1984-99. doi: 10.1158/1541-7786.MCR-09-0119. Epub 2009 Dec 8.

10.

Biphasic chromatin binding of histone chaperone FACT during eukaryotic chromatin DNA replication.

Kundu LR, Seki M, Watanabe N, Murofushi H, Furukohri A, Waga S, Score AJ, Blow JJ, Horikoshi M, Enomoto T, Tada S.

Biochim Biophys Acta. 2011 Jun;1813(6):1129-36. doi: 10.1016/j.bbamcr.2011.01.002. Epub 2011 Jan 11.

11.

Enhanced chromatin dynamics by FACT promotes transcriptional restart after UV-induced DNA damage.

Dinant C, Ampatziadis-Michailidis G, Lans H, Tresini M, Lagarou A, Grosbart M, Theil AF, van Cappellen WA, Kimura H, Bartek J, Fousteri M, Houtsmuller AB, Vermeulen W, Marteijn JA.

Mol Cell. 2013 Aug 22;51(4):469-79. doi: 10.1016/j.molcel.2013.08.007.

12.

The yeast and human FACT chromatin-reorganizing complexes solve R-loop-mediated transcription-replication conflicts.

Herrera-Moyano E, Mergui X, García-Rubio ML, Barroso S, Aguilera A.

Genes Dev. 2014 Apr 1;28(7):735-48. doi: 10.1101/gad.234070.113. Epub 2014 Mar 17.

13.

Tracking FACT and the RNA polymerase II elongation complex through chromatin in vivo.

Saunders A, Werner J, Andrulis ED, Nakayama T, Hirose S, Reinberg D, Lis JT.

Science. 2003 Aug 22;301(5636):1094-6.

14.

FACT facilitates chromatin transcription by RNA polymerases I and III.

Birch JL, Tan BC, Panov KI, Panova TB, Andersen JS, Owen-Hughes TA, Russell J, Lee SC, Zomerdijk JC.

EMBO J. 2009 Apr 8;28(7):854-65. doi: 10.1038/emboj.2009.33. Epub 2009 Feb 12.

15.

Genome-wide analysis of self-renewal in Drosophila neural stem cells by transgenic RNAi.

Neumüller RA, Richter C, Fischer A, Novatchkova M, Neumüller KG, Knoblich JA.

Cell Stem Cell. 2011 May 6;8(5):580-93. doi: 10.1016/j.stem.2011.02.022.

16.

Experimental analysis of hFACT action during Pol II transcription in vitro.

Hsieh FK, Kulaeva OI, Studitsky VM.

Methods Mol Biol. 2015;1276:315-26. doi: 10.1007/978-1-4939-2392-2_19.

17.

The chromatin-specific transcription elongation factor FACT comprises human SPT16 and SSRP1 proteins.

Orphanides G, Wu WH, Lane WS, Hampsey M, Reinberg D.

Nature. 1999 Jul 15;400(6741):284-8.

PMID:
10421373
18.

Targeting FACT complex suppresses mammary tumorigenesis in Her2/neu transgenic mice.

Koman IE, Commane M, Paszkiewicz G, Hoonjan B, Pal S, Safina A, Toshkov I, Purmal AA, Wang D, Liu S, Morrison C, Gudkov AV, Gurova KV.

Cancer Prev Res (Phila). 2012 Aug;5(8):1025-35. doi: 10.1158/1940-6207.CAPR-11-0529. Epub 2012 Jun 11.

19.

Drosophila FACT contributes to Hox gene expression through physical and functional interactions with GAGA factor.

Shimojima T, Okada M, Nakayama T, Ueda H, Okawa K, Iwamatsu A, Handa H, Hirose S.

Genes Dev. 2003 Jul 1;17(13):1605-16. Epub 2003 Jun 18.

20.

FACT Assists Base Excision Repair by Boosting the Remodeling Activity of RSC.

Charles Richard JL, Shukla MS, Menoni H, Ouararhni K, Lone IN, Roulland Y, Papin C, Ben Simon E, Kundu T, Hamiche A, Angelov D, Dimitrov S.

PLoS Genet. 2016 Jul 28;12(7):e1006221. doi: 10.1371/journal.pgen.1006221. eCollection 2016 Jul.

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