Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 94


Role of Fas-associated death domain-containing protein (FADD) phosphorylation in regulating glucose homeostasis: from proteomic discovery to physiological validation.

Yao C, Zhuang H, Du P, Cheng W, Yang B, Guan S, Hu Y, Zhu D, Christine M, Shi L, Hua ZC.

Mol Cell Proteomics. 2013 Oct;12(10):2689-700. doi: 10.1074/mcp.M113.029306. Epub 2013 Jul 4.


FADD phosphorylation impaired islet morphology and function.

Yao C, Zhuang H, Cheng W, Lin Y, Du P, Yang B, Huang X, Chen S, Hu Q, Hua ZC.

J Cell Physiol. 2015 Jul;230(7):1448-56. doi: 10.1002/jcp.24885.


Comparative proteomics analysis reveals roles for FADD in the regulation of energy metabolism and proteolysis pathway in mouse embryonic fibroblast.

Zhuang H, Gan Z, Jiang W, Zhang X, Hua ZC.

Proteomics. 2013 Aug;13(16):2398-413. doi: 10.1002/pmic.201300017. Epub 2013 Jul 11.


Functional specific roles of FADD: comparative proteomic analyses from knockout cell lines.

Zhuang H, Gan Z, Jiang W, Zhang X, Hua ZC.

Mol Biosyst. 2013 Aug;9(8):2063-78. doi: 10.1039/c3mb70023b. Epub 2013 May 21.


FADD is essential for glucose uptake and survival of thymocytes.

Zhang XY, Yang BY, Wang JY, Mo X, Zhang J, Hua ZC.

Biochem Biophys Res Commun. 2014 Aug 22;451(2):202-7. doi: 10.1016/j.bbrc.2014.07.092. Epub 2014 Jul 28.


Constitutive phosphorylation mutation in Fas-associated death domain (FADD) results in early cell cycle defects.

Osborn SL, Sohn SJ, Winoto A.

J Biol Chem. 2007 Aug 3;282(31):22786-92. Epub 2007 Jun 6.


Regulation of protein kinase C inactivation by Fas-associated protein with death domain.

Cheng W, Wang L, Zhang R, Du P, Yang B, Zhuang H, Tang B, Yao C, Yu M, Wang Y, Zhang J, Yin W, Li J, Zheng W, Lu M, Hua Z.

J Biol Chem. 2012 Jul 27;287(31):26126-35. doi: 10.1074/jbc.M112.342170. Epub 2012 May 11.


The death domain of FADD is essential for embryogenesis, lymphocyte development, and proliferation.

Imtiyaz HZ, Zhou X, Zhang H, Chen D, Hu T, Zhang J.

J Biol Chem. 2009 Apr 10;284(15):9917-26. doi: 10.1074/jbc.M900249200. Epub 2009 Feb 9.


FADD is a key regulator of lipid metabolism.

Zhuang H, Wang X, Zha D, Gan Z, Cai F, Du P, Yang Y, Yang B, Zhang X, Yao C, Zhou Y, Jiang C, Guan S, Zhang X, Zhang J, Jiang W, Hu Q, Hua ZC.

EMBO Mol Med. 2016 Aug 1;8(8):895-918. doi: 10.15252/emmm.201505924. Print 2016 Aug.


Effects of constitutive deletion of opioid receptors on the basal densities of Fas and Fas-associated protein with death domain (FADD) in the mouse brain: a delta-opioid tone inhibits FADD.

García-Fuster MJ, Ferrer-Alcón M, Martín M, Kieffer BL, Maldonado R, García-Sevilla JA.

Eur Neuropsychopharmacol. 2007 Apr;17(5):366-74. Epub 2006 Oct 9.


A critical role of Fas-associated protein with death domain phosphorylation in intracellular reactive oxygen species homeostasis and aging.

Cheng W, Zhang R, Yao C, He L, Jia K, Yang B, Du P, Zhuang H, Chen J, Liu Z, Ding X, Hua Z.

Antioxid Redox Signal. 2014 Jul 1;21(1):33-45. doi: 10.1089/ars.2013.5390. Epub 2014 Mar 6.


Phosphorylation of FADD (Fas-associated death domain protein) at serine 194 is increased in the prefrontal cortex of opiate abusers: relation to mitogen activated protein kinase, phosphoprotein enriched in astrocytes of 15 kDa, and Akt signaling pathways involved in neuroplasticity.

Ramos-Miguel A, García-Fuster MJ, Callado LF, La Harpe R, Meana JJ, García-Sevilla JA.

Neuroscience. 2009 Jun 16;161(1):23-38. doi: 10.1016/j.neuroscience.2009.03.028. Epub 2009 Mar 20.


The neuroplastic index p-FADD/FADD and phosphoprotein PEA-15, interacting at GABAA receptor, are upregulated in brain cortex during midazolam-induced hypnosis in mice.

Álvaro-Bartolomé M, García-Sevilla JA.

Eur Neuropsychopharmacol. 2015 Nov;25(11):2131-44. doi: 10.1016/j.euroneuro.2015.07.019. Epub 2015 Jul 31.


Self-renewal and differentiation of muscle satellite cells are regulated by the Fas-associated death domain.

Cheng W, Wang L, Yang B, Zhang R, Yao C, He L, Liu Z, Du P, Hammache K, Wen J, Li H, Xu Q, Hua Z.

J Biol Chem. 2014 Feb 21;289(8):5040-50. doi: 10.1074/jbc.M113.533448. Epub 2013 Dec 27.


Regulation of Fas receptor/Fas-associated protein with death domain apoptotic complex and associated signalling systems by cannabinoid receptors in the mouse brain.

Alvaro-Bartolomé M, Esteban S, García-Gutiérrez MS, Manzanares J, Valverde O, García-Sevilla JA.

Br J Pharmacol. 2010 Jun;160(3):643-56. doi: 10.1111/j.1476-5381.2010.00710.x.


Modulatory role of the anti-apoptotic protein kinase CK2 in the sub-cellular localization of Fas associated death domain protein (FADD).

Vilmont V, Filhol O, Hesse AM, Couté Y, Hue C, Rémy-Tourneur L, Mistou S, Cochet C, Chiocchia G.

Biochim Biophys Acta. 2015 Nov;1853(11 Pt A):2885-96. doi: 10.1016/j.bbamcr.2015.08.001. Epub 2015 Aug 5.


Irisin inhibits hepatic gluconeogenesis and increases glycogen synthesis via the PI3K/Akt pathway in type 2 diabetic mice and hepatocytes.

Liu TY, Shi CX, Gao R, Sun HJ, Xiong XQ, Ding L, Chen Q, Li YH, Wang JJ, Kang YM, Zhu GQ.

Clin Sci (Lond). 2015 Nov;129(10):839-50. doi: 10.1042/CS20150009. Epub 2015 Jul 13.


Phosphorylation of FADD by the kinase CK1α promotes KRASG12D-induced lung cancer.

Bowman BM, Sebolt KA, Hoff BA, Boes JL, Daniels DL, Heist KA, Galbán CJ, Patel RM, Zhang J, Beer DG, Ross BD, Rehemtulla A, Galbán S.

Sci Signal. 2015 Jan 27;8(361):ra9. doi: 10.1126/scisignal.2005607. Erratum in: Sci Signal. 2015 Mar 17;8(368):er3.


Calmodulin mediates Fas-induced FADD-independent survival signaling in pancreatic cancer cells via activation of Src-extracellular signal-regulated kinase (ERK).

Yuan K, Jing G, Chen J, Liu H, Zhang K, Li Y, Wu H, McDonald JM, Chen Y.

J Biol Chem. 2011 Jul 15;286(28):24776-84. doi: 10.1074/jbc.M110.202804. Epub 2011 May 25.

Supplemental Content

Support Center