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Items: 1 to 20 of 127


Antitumour effects of Yangzheng Xiaoji in human osteosarcoma: the pivotal role of focal adhesion kinase signalling.

Jiang WG, Ye L, Ji K, Ruge F, Wu Y, Gao Y, Ji J, Mason MD.

Oncol Rep. 2013 Sep;30(3):1405-13. doi: 10.3892/or.2013.2586. Epub 2013 Jul 3.


YangZheng XiaoJi exerts anti-tumour growth effects by antagonising the effects of HGF and its receptor, cMET, in human lung cancer cells.

Jiang WG, Ye L, Ruge F, Owen S, Martin T, Sun PH, Sanders AJ, Lane J, Satherley L, Weeks HP, Gao Y, Wei C, Wu Y, Mason MD.

J Transl Med. 2015 Aug 27;13:280. doi: 10.1186/s12967-015-0639-1.


Inhibitory effects of Yangzheng Xiaoji on angiogenesis and the role of the focal adhesion kinase pathway.

Jiang WG, Ye L, Ji K, Frewer N, Ji J, Mason MD.

Int J Oncol. 2012 Nov;41(5):1635-42. doi: 10.3892/ijo.2012.1627. Epub 2012 Sep 11.


Impact of Yangzheng Xiaoji on the adhesion and migration of human cancer cells: the role of the AKT signalling pathway.

Ye L, Ji K, Frewer N, Ji J, Jiang WG.

Anticancer Res. 2012 Jul;32(7):2537-43.


Heat shock protein 27 is a potential indicator for response to YangZheng XiaoJi and chemotherapy agents in cancer cells.

Owen S, Zhao H, Dart A, Wang Y, Ruge F, Gao Y, Wei C, Wu Y, Jiang WG.

Int J Oncol. 2016 Nov;49(5):1839-1847. doi: 10.3892/ijo.2016.3685. Epub 2016 Sep 6.


Expression of Sonic Hedgehog (SHH) in human lung cancer and the impact of YangZheng XiaoJi on SHH-mediated biological function of lung cancer cells and tumor growth.

Jiang WG, Ye L, Ruge F, Sun PH, Sanders AJ, Ji K, Lane J, Zhang L, Satherley L, Weeks HP, Zhi X, Gao Y, Wei C, Wu Y, Mason MD.

Anticancer Res. 2015 Mar;35(3):1321-31.


3-Hydroxyflavone inhibits human osteosarcoma U2OS and 143B cells metastasis by affecting EMT and repressing u-PA/MMP-2 via FAK-Src to MEK/ERK and RhoA/MLC2 pathways and reduces 143B tumor growth in vivo.

Lu KH, Chen PN, Hsieh YH, Lin CY, Cheng FY, Chiu PC, Chu SC, Hsieh YS.

Food Chem Toxicol. 2016 Nov;97:177-186. doi: 10.1016/j.fct.2016.09.006. Epub 2016 Sep 4.


Inhibition of Src phosphorylation alters metastatic potential of osteosarcoma in vitro but not in vivo.

Hingorani P, Zhang W, Gorlick R, Kolb EA.

Clin Cancer Res. 2009 May 15;15(10):3416-22. doi: 10.1158/1078-0432.CCR-08-1657. Epub 2009 May 15.


Maternal embryonic leucine zipper kinase enhances gastric cancer progression via the FAK/Paxillin pathway.

Du T, Qu Y, Li J, Li H, Su L, Zhou Q, Yan M, Li C, Zhu Z, Liu B.

Mol Cancer. 2014 May 4;13:100. doi: 10.1186/1476-4598-13-100.


4-Methoxydalbergione suppresses growth and induces apoptosis in human osteosarcoma cells in vitro and in vivo xenograft model through down-regulation of the JAK2/STAT3 pathway.

Park KR, Yun HM, Quang TH, Oh H, Lee DS, Auh QS, Kim EC.

Oncotarget. 2016 Feb 9;7(6):6960-71. doi: 10.18632/oncotarget.6873.


Contribution of the PI3K/MMPs/Ln-5γ2 and EphA2/FAK/Paxillin signaling pathways to tumor growth and vasculogenic mimicry of gallbladder carcinomas.

Lu XS, Sun W, Ge CY, Zhang WZ, Fan YZ.

Int J Oncol. 2013 Jun;42(6):2103-15. doi: 10.3892/ijo.2013.1897. Epub 2013 Apr 15.


Enhancement of malignant properties of human osteosarcoma cells with disialyl gangliosides GD2/GD3.

Shibuya H, Hamamura K, Hotta H, Matsumoto Y, Nishida Y, Hattori H, Furukawa K, Ueda M, Furukawa K.

Cancer Sci. 2012 Sep;103(9):1656-64. doi: 10.1111/j.1349-7006.2012.02344.x. Epub 2012 Jul 16.


Small GTP-binding protein, Rho, both increased and decreased cellular motility, activation of matrix metalloproteinase 2 and invasion of human osteosarcoma cells.

Matsumoto Y, Tanaka K, Harimaya K, Nakatani F, Matsuda S, Iwamoto Y.

Jpn J Cancer Res. 2001 Apr;92(4):429-38.


Antitumor effect of focal adhesion kinase inhibitor PF562271 against human osteosarcoma in vitro and in vivo.

Hu C, Chen X, Wen J, Gong L, Liu Z, Wang J, Liang J, Hu F, Zhou Q, Wei L, Shen Y, Zhang W.

Cancer Sci. 2017 Jul;108(7):1347-1356. doi: 10.1111/cas.13256. Epub 2017 Jun 8.


Focal adhesion kinase overexpression and its impact on human osteosarcoma.

Ren K, Lu X, Yao N, Chen Y, Yang A, Chen H, Zhang J, Wu S, Shi X, Wang C, Sun X.

Oncotarget. 2015 Oct 13;6(31):31085-103. doi: 10.18632/oncotarget.5044.


Artesunate inhibits growth and induces apoptosis in human osteosarcoma HOS cell line in vitro and in vivo.

Xu Q, Li ZX, Peng HQ, Sun ZW, Cheng RL, Ye ZM, Li WX.

J Zhejiang Univ Sci B. 2011 Apr;12(4):247-55. doi: 10.1631/jzus.B1000373.


Tetramethylpyrazine inhibits osteosarcoma cell proliferation via downregulation of NF-κB in vitro and in vivo.

Wang Y, Fu Q, Zhao W.

Mol Med Rep. 2013 Oct;8(4):984-8. doi: 10.3892/mmr.2013.1611. Epub 2013 Aug 2.


Extracellular pressure stimulates tumor cell adhesion in vitro by paxillin activation.

van Zyp Jv, Conway WC, Craig DH, van Zyp Nv, Thamilselvan V, Basson MD.

Cancer Biol Ther. 2006 Sep;5(9):1169-78. Epub 2006 Sep 6.


Inhibition of polo-like kinase 1 leads to the suppression of osteosarcoma cell growth in vitro and in vivo.

Liu X, Choy E, Harmon D, Yang S, Yang C, Mankin H, Hornicek FJ, Duan Z.

Anticancer Drugs. 2011 Jun;22(5):444-53. doi: 10.1097/CAD.0b013e32834513f4.


Evaluation of quercetin as a potential drug in osteosarcoma treatment.

Berndt K, Campanile C, Muff R, Strehler E, Born W, Fuchs B.

Anticancer Res. 2013 Apr;33(4):1297-306.


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