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Items: 1 to 20 of 126


The 3D genome shapes up for pluripotency.

Sexton T, Cavalli G.

Cell Stem Cell. 2013 Jul 3;13(1):3-4. doi: 10.1016/j.stem.2013.06.013.


Genome organization by Klf4 regulates transcription in pluripotent stem cells.

Huang D, Wei Z, Lu W.

Cell Cycle. 2013 Nov 1;12(21):3351-2. doi: 10.4161/cc.26577. Epub 2013 Sep 23. No abstract available.


Chromatin looping is needed for iPSC induction.

Hu JF, Hoffman AR.

Cell Cycle. 2014;13(1):1-2. doi: 10.4161/cc.27017. Epub 2013 Nov 14. No abstract available.


Klf4 organizes long-range chromosomal interactions with the oct4 locus in reprogramming and pluripotency.

Wei Z, Gao F, Kim S, Yang H, Lyu J, An W, Wang K, Lu W.

Cell Stem Cell. 2013 Jul 3;13(1):36-47. doi: 10.1016/j.stem.2013.05.010. Epub 2013 Jun 6.


Intrachromosomal looping is required for activation of endogenous pluripotency genes during reprogramming.

Zhang H, Jiao W, Sun L, Fan J, Chen M, Wang H, Xu X, Shen A, Li T, Niu B, Ge S, Li W, Cui J, Wang G, Sun J, Fan X, Hu X, Mrsny RJ, Hoffman AR, Hu JF.

Cell Stem Cell. 2013 Jul 3;13(1):30-5. doi: 10.1016/j.stem.2013.05.012. Epub 2013 Jun 6.


Dynamic regulation of human endogenous retroviruses mediates factor-induced reprogramming and differentiation potential.

Ohnuki M, Tanabe K, Sutou K, Teramoto I, Sawamura Y, Narita M, Nakamura M, Tokunaga Y, Nakamura M, Watanabe A, Yamanaka S, Takahashi K.

Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):12426-31. doi: 10.1073/pnas.1413299111. Epub 2014 Aug 5.


The pluripotent genome in three dimensions is shaped around pluripotency factors.

de Wit E, Bouwman BA, Zhu Y, Klous P, Splinter E, Verstegen MJ, Krijger PH, Festuccia N, Nora EP, Welling M, Heard E, Geijsen N, Poot RA, Chambers I, de Laat W.

Nature. 2013 Sep 12;501(7466):227-31. doi: 10.1038/nature12420. Epub 2013 Jul 24.


More synergetic cooperation of Yamanaka factors in induced pluripotent stem cells than in embryonic stem cells.

Huang J, Chen T, Liu X, Jiang J, Li J, Li D, Liu XS, Li W, Kang J, Pei G.

Cell Res. 2009 Oct;19(10):1127-38. doi: 10.1038/cr.2009.106. Epub 2009 Sep 8.


Facilitators and impediments of the pluripotency reprogramming factors' initial engagement with the genome.

Soufi A, Donahue G, Zaret KS.

Cell. 2012 Nov 21;151(5):994-1004. doi: 10.1016/j.cell.2012.09.045. Epub 2012 Nov 15.


Replacement of Oct4 by Tet1 during iPSC induction reveals an important role of DNA methylation and hydroxymethylation in reprogramming.

Gao Y, Chen J, Li K, Wu T, Huang B, Liu W, Kou X, Zhang Y, Huang H, Jiang Y, Yao C, Liu X, Lu Z, Xu Z, Kang L, Chen J, Wang H, Cai T, Gao S.

Cell Stem Cell. 2013 Apr 4;12(4):453-69. doi: 10.1016/j.stem.2013.02.005. Epub 2013 Mar 14.


Concise review: Induced pluripotent stem cells versus embryonic stem cells: close enough or yet too far apart?

Bilic J, Izpisua Belmonte JC.

Stem Cells. 2012 Jan;30(1):33-41. doi: 10.1002/stem.700. Review.


Genome-wide functional analysis reveals factors needed at the transition steps of induced reprogramming.

Yang CS, Chang KY, Rana TM.

Cell Rep. 2014 Jul 24;8(2):327-37. doi: 10.1016/j.celrep.2014.07.002. Epub 2014 Jul 17.


Epigenetic reprogramming of the germ cell nuclear factor gene is required for proper differentiation of induced pluripotent cells.

Wang H, Wang X, Xu X, Zwaka TP, Cooney AJ.

Stem Cells. 2013 Dec;31(12):2659-66. doi: 10.1002/stem.1367.


Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming.

Apostolou E, Ferrari F, Walsh RM, Bar-Nur O, Stadtfeld M, Cheloufi S, Stuart HT, Polo JM, Ohsumi TK, Borowsky ML, Kharchenko PV, Park PJ, Hochedlinger K.

Cell Stem Cell. 2013 Jun 6;12(6):699-712. doi: 10.1016/j.stem.2013.04.013. Epub 2013 May 9.


Genome-wide analysis reveals Sall4 to be a major regulator of pluripotency in murine-embryonic stem cells.

Yang J, Chai L, Fowles TC, Alipio Z, Xu D, Fink LM, Ward DC, Ma Y.

Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19756-61. doi: 10.1073/pnas.0809321105. Epub 2008 Dec 5.


Gata6 potently initiates reprograming of pluripotent and differentiated cells to extraembryonic endoderm stem cells.

Wamaitha SE, del Valle I, Cho LT, Wei Y, Fogarty NM, Blakeley P, Sherwood RI, Ji H, Niakan KK.

Genes Dev. 2015 Jun 15;29(12):1239-55. doi: 10.1101/gad.257071.114.


Direct reprogramming 101.

Takahashi K.

Dev Growth Differ. 2010 Apr;52(3):319-33. doi: 10.1111/j.1440-169X.2010.01169.x. Epub 2010 Mar 7. Review.


Rearranging the chromatin for pluripotency.

Ferrari F, Apostolou E, Park PJ, Hochedlinger K.

Cell Cycle. 2014;13(2):167-8. doi: 10.4161/cc.27028. Epub 2013 Nov 15. No abstract available.

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