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Items: 1 to 20 of 95

1.

[Neutrophil elastase inhibitor on proliferation and apoptosis of U937 cells].

Ma PP, Zhu D, Liu BZ, Zhong L, Zhu XY, Wang H, Zhang X, Gao YM, Hu XX.

Zhonghua Xue Ye Xue Za Zhi. 2013 Jun;34(6):507-11. doi: 10.3760/cma.j.issn.0253-2727.2013.06.011. Chinese.

PMID:
23827109
2.

Effects of elastase inhibitor on the epithelial cell apoptosis in bleomycin-induced pulmonary fibrosis.

Song JS, Kang CM, Rhee CK, Yoon HK, Kim YK, Moon HS, Park SH.

Exp Lung Res. 2009 Dec;35(10):817-29. doi: 10.3109/01902140902912527.

PMID:
19995276
3.

Protective effects of a selective neutrophil elastase inhibitor (sivelestat) on lipopolysaccharide-induced acute dysfunction of the pulmonary microcirculation.

Inoue Y, Seiyama A, Tanaka H, Ukai I, Akimau P, Nishino M, Shimazu T, Sugimoto H.

Crit Care Med. 2005 Aug;33(8):1814-22.

PMID:
16096460
4.

Inhaled neutrophil elastase inhibitor reduces oleic acid-induced acute lung injury in rats.

Tao W, Miao QB, Zhu YB, Shu YS.

Pulm Pharmacol Ther. 2012 Feb;25(1):99-103. doi: 10.1016/j.pupt.2011.12.006. Epub 2011 Dec 27.

PMID:
22210005
5.

Growth effect of neutrophil elastase on breast cancer: favorable action of sivelestat and application to anti-HER2 therapy.

Nawa M, Osada S, Morimitsu K, Nonaka K, Futamura M, Kawaguchi Y, Yoshida K.

Anticancer Res. 2012 Jan;32(1):13-9.

PMID:
22213283
6.

Neutrophil elastase inhibitor, sivelestat sodium hydrate prevents ischemia-reperfusion injury in the rat bladder.

Kono T, Okada S, Saito M.

Mol Cell Biochem. 2008 Apr;311(1-2):87-92. doi: 10.1007/s11010-007-9698-9. Epub 2007 Dec 30.

PMID:
18165924
7.

Sivelestat, a specific neutrophil elastase inhibitor, prevented phorbol myristate acetate-induced acute lung injury in conscious rabbits.

Hagio T, Matsumoto S, Nakao S, Matsuoka S, Kawabata K.

Pulm Pharmacol Ther. 2005;18(4):285-90.

PMID:
15777611
8.

Neutrophil elastase and its therapeutic effect on leukemia cells.

Jiang KL, Ma PP, Yang XQ, Zhong L, Wang H, Zhu XY, Liu BZ.

Mol Med Rep. 2015 Sep;12(3):4165-72. doi: 10.3892/mmr.2015.3946. Epub 2015 Jun 17.

9.

Sivelestat, a specific neutrophil elastase inhibitor, suppresses the growth of gastric carcinoma cells by preventing the release of transforming growth factor-alpha.

Wada Y, Yoshida K, Hihara J, Konishi K, Tanabe K, Ukon K, Taomoto J, Suzuki T, Mizuiri H.

Cancer Sci. 2006 Oct;97(10):1037-43. Epub 2006 Aug 17.

10.

Sivelestat reduces inflammatory mediators and preserves neutrophil deformability during simulated extracorporeal circulation.

Matsuzaki K, Hiramatsu Y, Homma S, Sato S, Shigeta O, Sakakibara Y.

Ann Thorac Surg. 2005 Aug;80(2):611-7.

PMID:
16039215
11.

Neutrophil elastase inhibitor (sivelestat) attenuates subsequent ventilator-induced lung injury in mice.

Sakashita A, Nishimura Y, Nishiuma T, Takenaka K, Kobayashi K, Kotani Y, Yokoyama M.

Eur J Pharmacol. 2007 Sep 24;571(1):62-71. Epub 2007 Jun 9.

PMID:
17599828
12.

[Pharmacological profile of a specific neutrophil elastase inhibitor, Sivelestat sodium hydrate].

Kawabata K, Hagio T, Matsuoka S.

Nihon Yakurigaku Zasshi. 2003 Aug;122(2):151-60. Review. Japanese.

PMID:
12890901
13.

A neutrophil elastase inhibitor, sivelestat, reduces lung injury following endotoxin-induced shock in rats by inhibiting HMGB1.

Hagiwara S, Iwasaka H, Togo K, Noguchi T.

Inflammation. 2008 Aug;31(4):227-34. doi: 10.1007/s10753-008-9069-z.

PMID:
18536984
14.

A neutrophil elastase inhibitor, sivelestat, improves leukocyte deformability in patients with acute lung injury.

Inoue Y, Tanaka H, Ogura H, Ukai I, Fujita K, Hosotsubo H, Shimazu T, Sugimoto H.

J Trauma. 2006 May;60(5):936-43; discussion 943.

PMID:
16688053
15.

A neutrophil elastase inhibitor, sivelestat, improved respiratory and cardiac function in pediatric cardiovascular surgery with cardiopulmonary bypass.

Toyama S, Hatori F, Shimizu A, Takagi T.

J Anesth. 2008;22(4):341-6. doi: 10.1007/s00540-008-0645-z. Epub 2008 Nov 15.

PMID:
19011770
16.

Effects of specific neutrophil elastase inhibitor, sivelestat sodium hydrate, in murine model of severe pneumococcal pneumonia.

Yanagihara K, Fukuda Y, Seki M, Izumikawa K, Miyazaki Y, Hirakata Y, Tsukamoto K, Yamada Y, Kamhira S, Kohno S.

Exp Lung Res. 2007 Mar;33(2):71-80.

PMID:
17454103
17.

Inhibition of neutrophil elastase reduces lung injury and bacterial count in hamsters.

Hagio T, Kishikawa K, Kawabata K, Tasaka S, Hashimoto S, Hasegawa N, Ishizaka A.

Pulm Pharmacol Ther. 2008 Dec;21(6):884-91. doi: 10.1016/j.pupt.2008.10.002. Epub 2008 Oct 17.

PMID:
18992355
18.

Effects of sivelestat sodium hydrate on the reduction of radiation pneumonitis.

Shimbo T, Inomata T, Takahashi M, Tatsumi T, Uesugi Y, Narabayashi I, Sonobe H.

Int J Mol Med. 2007 Dec;20(6):817-22.

PMID:
17982688
20.

Reevaluation of the efficacy and safety of the neutrophil elastase inhibitor, Sivelestat, for the treatment of acute lung injury associated with systemic inflammatory response syndrome; a phase IV study.

Aikawa N, Ishizaka A, Hirasawa H, Shimazaki S, Yamamoto Y, Sugimoto H, Shinozaki M, Taenaka N, Endo S, Ikeda T, Kawasaki Y.

Pulm Pharmacol Ther. 2011 Oct;24(5):549-54. doi: 10.1016/j.pupt.2011.03.001. Epub 2011 Apr 22.

PMID:
21540122

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