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Items: 1 to 20 of 107

1.

Host factor SAMHD1 restricts DNA viruses in non-dividing myeloid cells.

Hollenbaugh JA, Gee P, Baker J, Daly MB, Amie SM, Tate J, Kasai N, Kanemura Y, Kim DH, Ward BM, Koyanagi Y, Kim B.

PLoS Pathog. 2013;9(6):e1003481. doi: 10.1371/journal.ppat.1003481. Epub 2013 Jun 27.

2.

SAMHD1 restricts herpes simplex virus 1 in macrophages by limiting DNA replication.

Kim ET, White TE, Brandariz-Núñez A, Diaz-Griffero F, Weitzman MD.

J Virol. 2013 Dec;87(23):12949-56. doi: 10.1128/JVI.02291-13. Epub 2013 Sep 25.

3.

Restriction of diverse retroviruses by SAMHD1.

Gramberg T, Kahle T, Bloch N, Wittmann S, Müllers E, Daddacha W, Hofmann H, Kim B, Lindemann D, Landau NR.

Retrovirology. 2013 Mar 5;10:26. doi: 10.1186/1742-4690-10-26.

4.

SAMHD1 restricts HIV-1 replication and regulates interferon production in mouse myeloid cells.

Zhang R, Bloch N, Nguyen LA, Kim B, Landau NR.

PLoS One. 2014 Feb 19;9(2):e89558. doi: 10.1371/journal.pone.0089558. eCollection 2014 Feb 19.

5.

The retroviral restriction ability of SAMHD1, but not its deoxynucleotide triphosphohydrolase activity, is regulated by phosphorylation.

White TE, Brandariz-Nuñez A, Valle-Casuso JC, Amie S, Nguyen LA, Kim B, Tuzova M, Diaz-Griffero F.

Cell Host Microbe. 2013 Apr 17;13(4):441-51. doi: 10.1016/j.chom.2013.03.005.

6.

SAMHD1 restricts HIV-1 infection in dendritic cells (DCs) by dNTP depletion, but its expression in DCs and primary CD4+ T-lymphocytes cannot be upregulated by interferons.

St Gelais C, de Silva S, Amie SM, Coleman CM, Hoy H, Hollenbaugh JA, Kim B, Wu L.

Retrovirology. 2012 Dec 11;9:105. doi: 10.1186/1742-4690-9-105.

7.

Phosphorylation of murine SAMHD1 regulates its antiretroviral activity.

Wittmann S, Behrendt R, Eissmann K, Volkmann B, Thomas D, Ebert T, Cribier A, Benkirane M, Hornung V, Bouzas NF, Gramberg T.

Retrovirology. 2015 Dec 15;12:103. doi: 10.1186/s12977-015-0229-6.

8.

Anti-HIV host factor SAMHD1 regulates viral sensitivity to nucleoside reverse transcriptase inhibitors via modulation of cellular deoxyribonucleoside triphosphate (dNTP) levels.

Amie SM, Daly MB, Noble E, Schinazi RF, Bambara RA, Kim B.

J Biol Chem. 2013 Jul 12;288(28):20683-91. doi: 10.1074/jbc.M113.472159. Epub 2013 Jun 5.

9.

SAMHD1 specifically restricts retroviruses through its RNase activity.

Choi J, Ryoo J, Oh C, Hwang S, Ahn K.

Retrovirology. 2015 Jun 2;12:46. doi: 10.1186/s12977-015-0174-4.

10.

Inhibition of herpes simplex virus type 1 by the CDK6 inhibitor PD-0332991 (palbociclib) through the control of SAMHD1.

Badia R, Angulo G, Riveira-Muñoz E, Pujantell M, Puig T, Ramirez C, Torres-Torronteras J, Martí R, Pauls E, Clotet B, Ballana E, Esté JA.

J Antimicrob Chemother. 2016 Feb;71(2):387-94. doi: 10.1093/jac/dkv363. Epub 2015 Nov 4.

11.

SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx.

Laguette N, Sobhian B, Casartelli N, Ringeard M, Chable-Bessia C, Ségéral E, Yatim A, Emiliani S, Schwartz O, Benkirane M.

Nature. 2011 May 25;474(7353):654-7. doi: 10.1038/nature10117.

12.

SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates.

Lahouassa H, Daddacha W, Hofmann H, Ayinde D, Logue EC, Dragin L, Bloch N, Maudet C, Bertrand M, Gramberg T, Pancino G, Priet S, Canard B, Laguette N, Benkirane M, Transy C, Landau NR, Kim B, Margottin-Goguet F.

Nat Immunol. 2012 Feb 12;13(3):223-8. doi: 10.1038/ni.2236. Erratum in: Nat Immunol. 2013 Aug;14(8):877.

13.

HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase.

Goldstone DC, Ennis-Adeniran V, Hedden JJ, Groom HC, Rice GI, Christodoulou E, Walker PA, Kelly G, Haire LF, Yap MW, de Carvalho LP, Stoye JP, Crow YJ, Taylor IA, Webb M.

Nature. 2011 Nov 6;480(7377):379-82. doi: 10.1038/nature10623.

PMID:
22056990
14.

The deoxynucleotide triphosphohydrolase SAMHD1 is a major regulator of DNA precursor pools in mammalian cells.

Franzolin E, Pontarin G, Rampazzo C, Miazzi C, Ferraro P, Palumbo E, Reichard P, Bianchi V.

Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14272-7. doi: 10.1073/pnas.1312033110. Epub 2013 Jul 15.

15.

SAMHD1 specifically affects the antiviral potency of thymidine analog HIV reverse transcriptase inhibitors.

Ballana E, Badia R, Terradas G, Torres-Torronteras J, Ruiz A, Pauls E, Riveira-Muñoz E, Clotet B, Martí R, Esté JA.

Antimicrob Agents Chemother. 2014 Aug;58(8):4804-13. doi: 10.1128/AAC.03145-14. Epub 2014 Jun 9.

16.

GTP is the primary activator of the anti-HIV restriction factor SAMHD1.

Amie SM, Bambara RA, Kim B.

J Biol Chem. 2013 Aug 30;288(35):25001-6. doi: 10.1074/jbc.C113.493619. Epub 2013 Jul 23.

17.

Identification of cellular proteins interacting with the retroviral restriction factor SAMHD1.

St Gelais C, de Silva S, Hach JC, White TE, Diaz-Griffero F, Yount JS, Wu L.

J Virol. 2014 May;88(10):5834-44. doi: 10.1128/JVI.00155-14. Epub 2014 Mar 12. Erratum in: J Virol. 2014 Jul;88(13):7689.

18.

SAMHD1 host restriction factor: a link with innate immune sensing of retrovirus infection.

Sze A, Olagnier D, Lin R, van Grevenynghe J, Hiscott J.

J Mol Biol. 2013 Dec 13;425(24):4981-94. doi: 10.1016/j.jmb.2013.10.022. Epub 2013 Oct 23. Review.

PMID:
24161438
19.

SAMHD1: a novel antiviral factor in intrinsic immunity.

Chen Z, Zhang L, Ying S.

Future Microbiol. 2012 Sep;7(9):1117-26. doi: 10.2217/fmb.12.81. Review.

PMID:
22953710
20.

SAMHD1 knockout mice: modeling retrovirus restriction in vivo.

Wu L.

Retrovirology. 2013 Nov 20;10:142. doi: 10.1186/1742-4690-10-142.

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