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Cellular RNA binding proteins NS1-BP and hnRNP K regulate influenza A virus RNA splicing.

Tsai PL, Chiou NT, Kuss S, García-Sastre A, Lynch KW, Fontoura BM.

PLoS Pathog. 2013;9(6):e1003460. doi: 10.1371/journal.ppat.1003460. Epub 2013 Jun 27.


An A14U Substitution in the 3' Noncoding Region of the M Segment of Viral RNA Supports Replication of Influenza Virus with an NS1 Deletion by Modulating Alternative Splicing of M Segment mRNAs.

Zheng M, Wang P, Song W, Lau SY, Liu S, Huang X, Mok BW, Liu YC, Chen Y, Yuen KY, Chen H.

J Virol. 2015 Oct;89(20):10273-85. doi: 10.1128/JVI.00919-15. Epub 2015 Jul 29.


Quantitative proteomic analysis of the influenza A virus nonstructural proteins NS1 and NS2 during natural cell infection identifies PACT as an NS1 target protein and antiviral host factor.

Tawaratsumida K, Phan V, Hrincius ER, High AA, Webby R, Redecke V, Häcker H.

J Virol. 2014 Aug;88(16):9038-48. doi: 10.1128/JVI.00830-14. Epub 2014 Jun 4.


Influenza C virus NS1 protein upregulates the splicing of viral mRNAs.

Muraki Y, Furukawa T, Kohno Y, Matsuzaki Y, Takashita E, Sugawara K, Hongo S.

J Virol. 2010 Feb;84(4):1957-66. doi: 10.1128/JVI.01627-09. Epub 2009 Dec 9.


Identification of protein partners of the human immunodeficiency virus 1 tat/rev exon 3 leads to the discovery of a new HIV-1 splicing regulator, protein hnRNP K.

Marchand V, Santerre M, Aigueperse C, Fouillen L, Saliou JM, Van Dorsselaer A, Sanglier-Cianférani S, Branlant C, Motorin Y.

RNA Biol. 2011 Mar-Apr;8(2):325-42. Epub 2011 Mar 1.


The accumulation of influenza A virus segment 7 spliced mRNAs is regulated by the NS1 protein.

Robb NC, Fodor E.

J Gen Virol. 2012 Jan;93(Pt 1):113-8. doi: 10.1099/vir.0.035485-0. Epub 2011 Sep 14.


Splicing of influenza A virus NS1 mRNA is independent of the viral NS1 protein.

Robb NC, Jackson D, Vreede FT, Fodor E.

J Gen Virol. 2010 Sep;91(Pt 9):2331-40. doi: 10.1099/vir.0.022004-0. Epub 2010 Jun 2.


Recruitment of RED-SMU1 complex by Influenza A Virus RNA polymerase to control Viral mRNA splicing.

Fournier G, Chiang C, Munier S, Tomoiu A, Demeret C, Vidalain PO, Jacob Y, Naffakh N.

PLoS Pathog. 2014 Jun 12;10(6):e1004164. doi: 10.1371/journal.ppat.1004164. eCollection 2014 Jun. Erratum in: PLoS Pathog. 2014 Jul;10(7):e1004317.


The influenza virus NS1 protein: a novel inhibitor of pre-mRNA splicing.

Lu Y, Qian XY, Krug RM.

Genes Dev. 1994 Aug 1;8(15):1817-28.


The interactomes of influenza virus NS1 and NS2 proteins identify new host factors and provide insights for ADAR1 playing a supportive role in virus replication.

de Chassey B, Aublin-Gex A, Ruggieri A, Meyniel-Schicklin L, Pradezynski F, Davoust N, Chantier T, Tafforeau L, Mangeot PE, Ciancia C, Perrin-Cocon L, Bartenschlager R, André P, Lotteau V.

PLoS Pathog. 2013;9(7):e1003440. doi: 10.1371/journal.ppat.1003440. Epub 2013 Jul 4.


Mutations in the M-gene segment can substantially increase replication efficiency of NS1 deletion influenza A virus in MDCK cells.

van Wielink R, Harmsen MM, Martens DE, Peeters BP, Wijffels RH, Moormann RJ.

J Virol. 2012 Nov;86(22):12341-50. doi: 10.1128/JVI.01725-12. Epub 2012 Sep 5.


Imaging of mRNA-protein interactions in live cells using novel mCherry trimolecular fluorescence complementation systems.

Yin J, Zhu D, Zhang Z, Wang W, Fan J, Men D, Deng J, Wei H, Zhang XE, Cui Z.

PLoS One. 2013 Nov 15;8(11):e80851. doi: 10.1371/journal.pone.0080851. eCollection 2013.


Synergistic stimulation of HIV-1 rev-dependent export of unspliced mRNA to the cytoplasm by hnRNP A1.

Najera I, Krieg M, Karn J.

J Mol Biol. 1999 Feb 5;285(5):1951-64.


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