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Items: 1 to 20 of 106

1.

20-HETE induces remodeling of renal resistance arteries independent of blood pressure elevation in hypertension.

Ding Y, Wu CC, Garcia V, Dimitrova I, Weidenhammer A, Joseph G, Zhang F, Manthati VL, Falck JR, Capdevila JH, Schwartzman ML.

Am J Physiol Renal Physiol. 2013 Sep 1;305(5):F753-63. doi: 10.1152/ajprenal.00292.2013. Epub 2013 Jul 3.

2.

Androgen-dependent hypertension is mediated by 20-hydroxy-5,8,11,14-eicosatetraenoic acid-induced vascular dysfunction: role of inhibitor of kappaB Kinase.

Wu CC, Cheng J, Zhang FF, Gotlinger KH, Kelkar M, Zhang Y, Jat JL, Falck JR, Schwartzman ML.

Hypertension. 2011 Apr;57(4):788-94. doi: 10.1161/HYPERTENSIONAHA.110.161570. Epub 2011 Feb 14.

3.

Angiotensin II receptor blockade or deletion of vascular endothelial ACE does not prevent vascular dysfunction and remodeling in 20-HETE-dependent hypertension.

Garcia V, Joseph G, Shkolnik B, Ding Y, Zhang FF, Gotlinger K, Falck JR, Dakarapu R, Capdevila JH, Bernstein KE, Schwartzman ML.

Am J Physiol Regul Integr Comp Physiol. 2015 Jul 1;309(1):R71-8. doi: 10.1152/ajpregu.00039.2015. Epub 2015 Apr 29.

4.

Androgen-sensitive hypertension associates with upregulated vascular CYP4A12-20-HETE synthase.

Wu CC, Mei S, Cheng J, Ding Y, Weidenhammer A, Garcia V, Zhang F, Gotlinger K, Manthati VL, Falck JR, Capdevila JH, Schwartzman ML.

J Am Soc Nephrol. 2013 Jul;24(8):1288-96. doi: 10.1681/ASN.2012070714. Epub 2013 May 2.

5.

Renal vascular cytochrome P450-derived eicosanoids in androgen-induced hypertension.

Singh H, Schwartzman ML.

Pharmacol Rep. 2008 Jan-Feb;60(1):29-37.

6.

Vascular cytochrome P450 4A expression and 20-hydroxyeicosatetraenoic acid synthesis contribute to endothelial dysfunction in androgen-induced hypertension.

Singh H, Cheng J, Deng H, Kemp R, Ishizuka T, Nasjletti A, Schwartzman ML.

Hypertension. 2007 Jul;50(1):123-9. Epub 2007 Jun 4.

7.

Androgen-induced hypertension in angiotensinogen deficient mice: role of 20-HETE and EETS.

Garcia V, Cheng J, Weidenhammer A, Ding Y, Wu CC, Zhang F, Gotlinger K, Falck JR, Schwartzman ML.

Prostaglandins Other Lipid Mediat. 2015 Jan-Mar;116-117:124-30. doi: 10.1016/j.prostaglandins.2014.12.001. Epub 2014 Dec 17.

8.

20-HETE and CYP4A2 ω-hydroxylase contribute to the elevated blood pressure in hyperandrogenemic female rats.

Dalmasso C, Maranon R, Patil C, Moulana M, Romero DG, Reckelhoff JF.

Am J Physiol Renal Physiol. 2016 Jul 1;311(1):F71-7. doi: 10.1152/ajprenal.00458.2015. Epub 2016 May 18.

9.

CYP4A2-induced hypertension is 20-hydroxyeicosatetraenoic acid- and angiotensin II-dependent.

Sodhi K, Wu CC, Cheng J, Gotlinger K, Inoue K, Goli M, Falck JR, Abraham NG, Schwartzman ML.

Hypertension. 2010 Nov;56(5):871-8. doi: 10.1161/HYPERTENSIONAHA.110.154559. Epub 2010 Sep 13.

10.

Contribution of iNOS/sGC/PKG pathway, COX-2, CYP4A1, and gp91(phox) to the protective effect of 5,14-HEDGE, a 20-HETE mimetic, against vasodilation, hypotension, tachycardia, and inflammation in a rat model of septic shock.

Tunctan B, Korkmaz B, Sari AN, Kacan M, Unsal D, Serin MS, Buharalioglu CK, Sahan-Firat S, Cuez T, Schunck WH, Manthati VL, Falck JR, Malik KU.

Nitric Oxide. 2013 Sep 1;33:18-41. doi: 10.1016/j.niox.2013.05.001. Epub 2013 May 14.

11.

Transfection of CYP4A1 cDNA increases vascular reactivity in renal interlobar arteries.

Kaide J, Wang MH, Wang JS, Zhang F, Gopal VR, Falck JR, Nasjletti A, Laniado-Schwartzman M.

Am J Physiol Renal Physiol. 2003 Jan;284(1):F51-6. Epub 2002 Sep 3.

12.

Androgen-sensitive hypertension associated with soluble guanylate cyclase-α1 deficiency is mediated by 20-HETE.

Dordea AC, Vandenwijngaert S, Garcia V, Tainsh RE, Nathan DI, Allen K, Raher MJ, Tainsh LT, Zhang F, Lieb WS, Mikelman S, Kirby A, Stevens C, Thoonen R, Hindle AG, Sips PY, Falck JR, Daly MJ, Brouckaert P, Bloch KD, Bloch DB, Malhotra R, Schwartzman ML, Buys ES.

Am J Physiol Heart Circ Physiol. 2016 Jun 1;310(11):H1790-800. doi: 10.1152/ajpheart.00877.2015. Epub 2016 May 3.

13.

Endothelial-specific CYP4A2 overexpression leads to renal injury and hypertension via increased production of 20-HETE.

Inoue K, Sodhi K, Puri N, Gotlinger KH, Cao J, Rezzani R, Falck JR, Abraham NG, Laniado-Schwartzman M.

Am J Physiol Renal Physiol. 2009 Oct;297(4):F875-84. doi: 10.1152/ajprenal.00364.2009. Epub 2009 Aug 12.

14.

Inhibitors of 20-HETE formation promote salt-sensitive hypertension in rats.

Hoagland KM, Flasch AK, Roman RJ.

Hypertension. 2003 Oct;42(4):669-73. Epub 2003 Jul 21.

15.

The role of 20-HETE in androgen-mediated hypertension.

Wu CC, Schwartzman ML.

Prostaglandins Other Lipid Mediat. 2011 Nov;96(1-4):45-53. doi: 10.1016/j.prostaglandins.2011.06.006. Epub 2011 Jun 22. Review.

16.

20-Hydroxyeicosatetraenoic acid inhibition attenuates balloon injury-induced neointima formation and vascular remodeling in rat carotid arteries.

Orozco LD, Liu H, Perkins E, Johnson DA, Chen BB, Fan F, Baker RC, Roman RJ.

J Pharmacol Exp Ther. 2013 Jul;346(1):67-74. doi: 10.1124/jpet.113.203844. Epub 2013 May 8.

17.

Hypertension is a major contributor to 20-hydroxyeicosatetraenoic acid-mediated kidney injury in diabetic nephropathy.

Gangadhariah MH, Luther JM, Garcia V, Paueksakon P, Zhang MZ, Hayward SW, Love HD, Falck JR, Manthati VL, Imig JD, Schwartzman ML, Zent R, Capdevila JH, Pozzi A.

J Am Soc Nephrol. 2015 Mar;26(3):597-610. doi: 10.1681/ASN.2013090980. Epub 2014 Jul 28.

18.

Role of 20-hydroxyeicosatetraenoic acid in altering vascular reactivity in diabetes.

Yousif MH, Benter IF, Dunn KM, Dahly-Vernon AJ, Akhtar S, Roman RJ.

Auton Autacoid Pharmacol. 2009 Jan;29(1-2):1-12. doi: 10.1111/j.1474-8673.2009.00426.x. Erratum in: Auton Autacoid Pharmacol. 2009 Jul;29(3):141.

19.

The Blood Pressure-Lowering Effect of 20-HETE Blockade in Cyp4a14(-/-) Mice Is Associated with Natriuresis.

Pandey V, Garcia V, Gilani A, Mishra P, Zhang FF, Paudyal MP, Falck JR, Nasjletti A, Wang WH, Schwartzman ML.

J Pharmacol Exp Ther. 2017 Dec;363(3):412-418. doi: 10.1124/jpet.117.243618. Epub 2017 Sep 14.

PMID:
28912346
20.

20-HETE contributes to myogenic activation of skeletal muscle resistance arteries in Brown Norway and Sprague-Dawley rats.

Frisbee JC, Roman RJ, Falck JR, Krishna UM, Lombard JH.

Microcirculation. 2001 Feb;8(1):45-55.

PMID:
11296852

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