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Items: 1 to 20 of 90

1.

A noncanonical, GSK3-independent pathway controls postprandial hepatic glycogen deposition.

Wan M, Leavens KF, Hunter RW, Koren S, von Wilamowitz-Moellendorff A, Lu M, Satapati S, Chu Q, Sakamoto K, Burgess SC, Birnbaum MJ.

Cell Metab. 2013 Jul 2;18(1):99-105. doi: 10.1016/j.cmet.2013.06.001.

2.
3.

Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis.

McManus EJ, Sakamoto K, Armit LJ, Ronaldson L, Shpiro N, Marquez R, Alessi DR.

EMBO J. 2005 Apr 20;24(8):1571-83. Epub 2005 Mar 24.

4.

Analysis of hepatic gene transcription in mice expressing insulin-insensitive GSK3.

Lipina C, Huang X, Finlay D, McManus EJ, Alessi DR, Sutherland C.

Biochem J. 2005 Dec 15;392(Pt 3):633-9.

5.

Akt2 influences glycogen synthase activity in human skeletal muscle through regulation of NH₂-terminal (sites 2 + 2a) phosphorylation.

Friedrichsen M, Birk JB, Richter EA, Ribel-Madsen R, Pehmøller C, Hansen BF, Beck-Nielsen H, Hirshman MF, Goodyear LJ, Vaag A, Poulsen P, Wojtaszewski JF.

Am J Physiol Endocrinol Metab. 2013 Mar 15;304(6):E631-9. doi: 10.1152/ajpendo.00494.2012. Epub 2013 Jan 15.

6.

Brain insulin action augments hepatic glycogen synthesis without suppressing glucose production or gluconeogenesis in dogs.

Ramnanan CJ, Saraswathi V, Smith MS, Donahue EP, Farmer B, Farmer TD, Neal D, Williams PE, Lautz M, Mari A, Cherrington AD, Edgerton DS.

J Clin Invest. 2011 Sep;121(9):3713-23. doi: 10.1172/JCI45472. Epub 2011 Aug 25.

7.

Role of Akt2 in contraction-stimulated cell signaling and glucose uptake in skeletal muscle.

Sakamoto K, Arnolds DE, Fujii N, Kramer HF, Hirshman MF, Goodyear LJ.

Am J Physiol Endocrinol Metab. 2006 Nov;291(5):E1031-7. Epub 2006 Jun 27.

8.

Zinc rescue of Akt2 gene deletion-linked murine cardiac dysfunction and pathological changes is metallothionein-dependent.

Sun W, Miao X, Zhou S, Zhang L, Epstein PN, Mellen N, Zheng Y, Fu Y, Wang Y, Cai L.

J Mol Cell Cardiol. 2014 Sep;74:88-97. doi: 10.1016/j.yjmcc.2014.04.023. Epub 2014 May 10.

PMID:
24819347
10.

FGF19 as a postprandial, insulin-independent activator of hepatic protein and glycogen synthesis.

Kir S, Beddow SA, Samuel VT, Miller P, Previs SF, Suino-Powell K, Xu HE, Shulman GI, Kliewer SA, Mangelsdorf DJ.

Science. 2011 Mar 25;331(6024):1621-4. doi: 10.1126/science.1198363.

11.

Acute activation of central GLP-1 receptors enhances hepatic insulin action and insulin secretion in high-fat-fed, insulin resistant mice.

Burmeister MA, Ferre T, Ayala JE, King EM, Holt RM, Ayala JE.

Am J Physiol Endocrinol Metab. 2012 Feb 1;302(3):E334-43. doi: 10.1152/ajpendo.00409.2011. Epub 2011 Nov 15.

12.

Reduced hepatic lipid content in Pten-haplodeficient mice because of enhanced AKT2/PKBβ activation in skeletal muscle.

Schultze SM, Dietrich M, Hynx D, Geier A, Niessen M, Spinas GA, Hemmings BA, Tschopp O.

Liver Int. 2015 Apr;35(4):1354-66. doi: 10.1111/liv.12600. Epub 2014 Jun 24.

PMID:
24845341
13.

Suppression of hepatic glucose production by human neutrophil alpha-defensins through a signaling pathway distinct from insulin.

Liu HY, Collins QF, Moukdar F, Zhuo D, Han J, Hong T, Collins S, Cao W.

J Biol Chem. 2008 May 2;283(18):12056-63. doi: 10.1074/jbc.M801033200. Epub 2008 Mar 17.

14.

Somatostatin receptor subtype-2-deficient mice with diet-induced obesity have hyperglycemia, nonfasting hyperglucagonemia, and decreased hepatic glycogen deposition.

Singh V, Grötzinger C, Nowak KW, Zacharias S, Göncz E, Pless G, Sauer IM, Eichhorn I, Pfeiffer-Guglielmi B, Hamprecht B, Wiedenmann B, Plöckinger U, Strowski MZ.

Endocrinology. 2007 Aug;148(8):3887-99. Epub 2007 May 24.

PMID:
17525126
15.

Role of the PDK1-PKB-GSK3 pathway in regulating glycogen synthase and glucose uptake in the heart.

Mora A, Sakamoto K, McManus EJ, Alessi DR.

FEBS Lett. 2005 Jul 4;579(17):3632-8.

16.

Mechanisms of liver and muscle insulin resistance induced by chronic high-fat feeding.

Oakes ND, Cooney GJ, Camilleri S, Chisholm DJ, Kraegen EW.

Diabetes. 1997 Nov;46(11):1768-74.

PMID:
9356024
17.

Pathogenesis of prediabetes: role of the liver in isolated fasting hyperglycemia and combined fasting and postprandial hyperglycemia.

Basu R, Barosa C, Jones J, Dube S, Carter R, Basu A, Rizza RA.

J Clin Endocrinol Metab. 2013 Mar;98(3):E409-17. doi: 10.1210/jc.2012-3056. Epub 2013 Jan 23.

18.

Relative contribution of glycogenolysis and gluconeogenesis to hepatic glucose production in control and diabetic rats. A re-examination in the presence of euglycaemia.

Giaccari A, Morviducci L, Pastore L, Zorretta D, Sbraccia P, Maroccia E, Buongiorno A, Tamburrano G.

Diabetologia. 1998 Mar;41(3):307-14.

PMID:
9541171
19.

Mechanism by which glucose and insulin inhibit net hepatic glycogenolysis in humans.

Petersen KF, Laurent D, Rothman DL, Cline GW, Shulman GI.

J Clin Invest. 1998 Mar 15;101(6):1203-9.

20.

Distinct mechanisms of glucose lowering by specific agonists for peroxisomal proliferator activated receptor gamma and retinoic acid X receptors.

Li X, Hansen PA, Xi L, Chandraratna RA, Burant CF.

J Biol Chem. 2005 Nov 18;280(46):38317-27. Epub 2005 Sep 22.

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