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Items: 1 to 20 of 100

1.

Synthesis and biological evaluation of a new series of highly functionalized 7'-homo-anhydrovinblastine derivatives.

Gherbovet O, Coderch C, García Alvarez MC, Bignon J, Thoret S, Martin MT, Guéritte F, Gago F, Roussi F.

J Med Chem. 2013 Aug 8;56(15):6088-100. doi: 10.1021/jm4004347. Epub 2013 Jul 18.

PMID:
23822556
2.

Synthesis and biological evaluation of C-13' substituted 7'-homo-anhydrovinblastine derivatives.

Gherbovet O, La Spisa F, Thoret S, Alvarez MCG, Levaique H, Bignon J, Roussi F.

Bioorg Med Chem Lett. 2015 Apr 15;25(8):1771-1773. doi: 10.1016/j.bmcl.2015.02.045. Epub 2015 Mar 7.

PMID:
25804719
3.

One-pot synthesis of vinca alkaloids-phomopsin hybrids.

Gherbovet O, Coderch C, García Alvarez MC, Bignon J, Thoret S, Guéritte F, Gago F, Roussi F.

J Med Chem. 2014 Jun 26;57(12):5470-6. doi: 10.1021/jm500530v. Epub 2014 Jun 10.

PMID:
24871162
4.

Synthesis and structure-activity relationship studies of cytotoxic anhydrovinblastine amide derivatives.

Shao Y, Zhang HK, Ding H, Quan HT, Lou LG, Hu LH.

J Nat Prod. 2009 Jun;72(6):1170-7. doi: 10.1021/np900157t.

PMID:
19499938
5.

Synthesis and structure-activity relationship studies of cytotoxic ester and ether anhydrovinblastine derivatives.

Zhang HK, Shao Y, Ding H, Hu LH.

J Nat Prod. 2008 Oct;71(10):1669-76. doi: 10.1021/np800284h. Epub 2008 Sep 4.

PMID:
18771244
6.

Synthesis and antiproliferative evaluation of pyrazolo[1,5-a]-1,3,5-triazine myoseverin derivatives.

Popowycz F, Schneider C, Debonis S, Skoufias DA, Kozielski F, Galmarini CM, Joseph B.

Bioorg Med Chem. 2009 May 1;17(9):3471-8. doi: 10.1016/j.bmc.2009.03.007. Epub 2009 Mar 10.

PMID:
19349183
7.

Synthesis and biological evaluation of 1-phenyl-1,2,3,4-dihydroisoquinoline compounds as tubulin polymerization inhibitors.

Zheng CH, Chen J, Liu J, Zhou XT, Liu N, Shi D, Huang JJ, Lv JG, Zhu J, Zhou YJ.

Arch Pharm (Weinheim). 2012 Jun;345(6):454-62. doi: 10.1002/ardp.201100169. Epub 2012 Mar 13.

PMID:
22415658
8.

Synthesis and biological evaluation of a series of podophyllotoxins derivatives as a class of potent antitubulin agents.

Liu Y, Wei D, Zhao Y, Cheng W, Lu Y, Ma Y, Li X, Han C, Wei Y, Cao H, Zhao C.

Bioorg Med Chem. 2012 Nov 1;20(21):6285-95. doi: 10.1016/j.bmc.2012.09.009. Epub 2012 Sep 13.

PMID:
23022053
9.

Synthesis and structure-activity relationship studies of cytotoxic vinorelbine amide analogues.

Hu L, Song W, Meng Y, Guo D, Liu X, Hu L.

Bioorg Med Chem Lett. 2012 Dec 15;22(24):7547-50. doi: 10.1016/j.bmcl.2012.10.024. Epub 2012 Oct 17.

PMID:
23107481
10.

Inhibitors of tubulin polymerization: synthesis and biological evaluation of hybrids of vindoline, anhydrovinblastine and vinorelbine with thiocolchicine, podophyllotoxin and baccatin III.

Passarella D, Giardini A, Peretto B, Fontana G, Sacchetti A, Silvani A, Ronchi C, Cappelletti G, Cartelli D, Borlak J, Danieli B.

Bioorg Med Chem. 2008 Jun 1;16(11):6269-85. doi: 10.1016/j.bmc.2008.04.025. Epub 2008 May 28.

PMID:
18468444
11.

Synthesis and antimitotic and tubulin interaction profiles of novel pinacol derivatives of podophyllotoxins.

Abad A, López-Pérez JL, del Olmo E, García-Fernández LF, Francesch A, Trigili C, Barasoain I, Andreu JM, Díaz JF, San Feliciano A.

J Med Chem. 2012 Aug 9;55(15):6724-37. doi: 10.1021/jm2017573. Epub 2012 Jul 23.

PMID:
22607205
12.

Synthesis and biological evaluation of colchicine B-ring analogues tethered with halogenated benzyl moieties.

Cosentino L, Redondo-Horcajo M, Zhao Y, Santos AR, Chowdury KF, Vinader V, Abdallah QM, Abdel-Rahman H, Fournier-Dit-Chabert J, Shnyder SD, Loadman PM, Fang WS, Díaz JF, Barasoain I, Burns PA, Pors K.

J Med Chem. 2012 Dec 27;55(24):11062-6. doi: 10.1021/jm301151t. Epub 2012 Dec 7.

PMID:
23176628
13.

Synthesis of macrocyclic bisbibenzyl derivatives and their anticancer effects as anti-tubulin agents.

Jiang J, Sun B, Wang YY, Cui M, Zhang L, Cui CZ, Wang YF, Liu XG, Lou HX.

Bioorg Med Chem. 2012 Apr 1;20(7):2382-91. doi: 10.1016/j.bmc.2012.02.004. Epub 2012 Feb 9.

PMID:
22365913
14.

Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents.

Romagnoli R, Baraldi PG, Pavani MG, Tabrizi MA, Preti D, Fruttarolo F, Piccagli L, Jung MK, Hamel E, Borgatti M, Gambari R.

J Med Chem. 2006 Jun 29;49(13):3906-15.

PMID:
16789746
15.

Design, synthesis, and biological evaluation of thiophene analogues of chalcones.

Romagnoli R, Baraldi PG, Carrion MD, Cara CL, Cruz-Lopez O, Preti D, Tolomeo M, Grimaudo S, Di Cristina A, Zonta N, Balzarini J, Brancale A, Sarkar T, Hamel E.

Bioorg Med Chem. 2008 May 15;16(10):5367-76. doi: 10.1016/j.bmc.2008.04.026. Epub 2008 Apr 15.

PMID:
18440234
16.

Synthesis, biological evaluation and molecular docking studies of resveratrol derivatives possessing curcumin moiety as potent antitubulin agents.

Ruan BF, Lu X, Li TT, Tang JF, Wei Y, Wang XL, Zheng SL, Yao RS, Zhu HL.

Bioorg Med Chem. 2012 Jan 15;20(2):1113-21. doi: 10.1016/j.bmc.2011.11.017. Epub 2011 Dec 1.

PMID:
22189271
17.

Design, synthesis, and biological evaluation of novel N-γ-carboline arylsulfonamides as anticancer agents.

Chen J, Liu T, Wu R, Lou J, Cao J, Dong X, Yang B, He Q, Hu Y.

Bioorg Med Chem. 2010 Dec 15;18(24):8478-84. doi: 10.1016/j.bmc.2010.10.047. Epub 2010 Oct 25.

PMID:
21067933
18.

Synthesis and biological evaluation of vinca alkaloids and phomopsin hybrids.

Ngo QA, Roussi F, Cormier A, Thoret S, Knossow M, Guénard D, Guéritte F.

J Med Chem. 2009 Jan 8;52(1):134-42. doi: 10.1021/jm801064y.

PMID:
19072542
19.

The synthesis of Navelbine prototype of a new series of vinblastine derivatives.

Potier P.

Semin Oncol. 1989 Apr;16(2 Suppl 4):2-4. No abstract available.

PMID:
2540531
20.

Synthesis and biological evaluation of C-12' substituted vinflunine derivatives.

Lei XS, Yu XD, Yin L, Liu ZH, Tang PC.

Bioorg Med Chem Lett. 2008 Aug 15;18(16):4602-5. doi: 10.1016/j.bmcl.2008.07.025. Epub 2008 Jul 12.

PMID:
18653334

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