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Natural killer cells in HIV controller patients express an activated effector phenotype and do not up-regulate NKp44 on IL-2 stimulation.

Marras F, Nicco E, Bozzano F, Di Biagio A, Dentone C, Pontali E, Boni S, Setti M, Orofino G, Mantia E, Bartolacci V, Bisio F, Riva A, Biassoni R, Moretta L, De Maria A.

Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11970-5. doi: 10.1073/pnas.1302090110. Epub 2013 Jul 1.


Specific phenotypic and functional features of natural killer cells from HIV-infected long-term nonprogressors and HIV controllers.

Vieillard V, Fausther-Bovendo H, Samri A, Debré P; French Asymptomatiques à Long Terme (ALT) ANRS-CO15 Study Group.

J Acquir Immune Defic Syndr. 2010 Apr;53(5):564-73. doi: 10.1097/QAI.0b013e3181d0c5b4.


Celiac Disease-Related Inflammation Is Marked by Reduction of Nkp44/Nkp46-Double Positive Natural Killer Cells.

Marafini I, Monteleone I, Di Fusco D, Sedda S, Cupi ML, Fina D, Paoluzi AO, Pallone F, Monteleone G.

PLoS One. 2016 May 12;11(5):e0155103. doi: 10.1371/journal.pone.0155103. eCollection 2016.


Influence of in vitro IL-2 or IL-15 alone or in combination with Hsp-70-derived 14-mer peptide (TKD) on the expression of NK cell activatory and inhibitory receptors.

Hromadnikova I, Pirkova P, Sedlackova L.

Mediators Inflamm. 2013;2013:405295. doi: 10.1155/2013/405295. Epub 2013 Feb 17.


Lysis of HIV-1-infected autologous CD4+ primary T cells by interferon-alpha-activated NK cells requires NKp46 and NKG2D.

Tomescu C, Mavilio D, Montaner LJ.

AIDS. 2015 Sep 10;29(14):1767-73. doi: 10.1097/QAD.0000000000000777.


Expressions of natural cytotoxicity receptors and NKG2D on decidual natural killer cells in patients having spontaneous abortions.

Zhang Y, Zhao A, Wang X, Shi G, Jin H, Lin Q.

Fertil Steril. 2008 Nov;90(5):1931-7. Epub 2007 Nov 26.


Balance between activating NKG2D, DNAM-1, NKp44 and NKp46 and inhibitory CD94/NKG2A receptors determine natural killer degranulation towards rheumatoid arthritis synovial fibroblasts.

Nielsen N, Pascal V, Fasth AE, Sundström Y, Galsgaard ED, Ahern D, Andersen M, Baslund B, Bartels EM, Bliddal H, Feldmann M, Malmström V, Berg L, Spee P, Söderström K.

Immunology. 2014 Aug;142(4):581-93. doi: 10.1111/imm.12271.


Overexpression of CD158 and NKG2A Inhibitory Receptors and Underexpression of NKG2D and NKp46 Activating Receptors on NK Cells in Acute Myeloid Leukemia.

Sandoval-Borrego D, Moreno-Lafont MC, Vazquez-Sanchez EA, Gutierrez-Hoya A, López-Santiago R, Montiel-Cervantes LA, Ramírez-Saldaña M, Vela-Ojeda J.

Arch Med Res. 2016 Jan;47(1):55-64. doi: 10.1016/j.arcmed.2016.02.001. Epub 2016 Feb 12.


Imbalance of NKp44(+)NKp46(-) and NKp44(-)NKp46(+) natural killer cells in the intestinal mucosa of patients with Crohn's disease.

Takayama T, Kamada N, Chinen H, Okamoto S, Kitazume MT, Chang J, Matuzaki Y, Suzuki S, Sugita A, Koganei K, Hisamatsu T, Kanai T, Hibi T.

Gastroenterology. 2010 Sep;139(3):882-92, 892.e1-3. doi: 10.1053/j.gastro.2010.05.040. Epub 2010 Jun 1.


Activated gammadelta T cells express the natural cytotoxicity receptor natural killer p 44 and show cytotoxic activity against myeloma cells.

von Lilienfeld-Toal M, Nattermann J, Feldmann G, Sievers E, Frank S, Strehl J, Schmidt-Wolf IG.

Clin Exp Immunol. 2006 Jun;144(3):528-33.


Human NK cytotoxicity against porcine cells is triggered by NKp44 and NKG2D.

Forte P, Lilienfeld BG, Baumann BC, Seebach JD.

J Immunol. 2005 Oct 15;175(8):5463-70.


The impaired NK cell cytolytic function in viremic HIV-1 infection is associated with a reduced surface expression of natural cytotoxicity receptors (NKp46, NKp30 and NKp44).

De Maria A, Fogli M, Costa P, Murdaca G, Puppo F, Mavilio D, Moretta A, Moretta L.

Eur J Immunol. 2003 Sep;33(9):2410-8.


Activation of natural killer cells by hepatitis C virus particles in vitro.

Farag MM, Weigand K, Encke J, Momburg F.

Clin Exp Immunol. 2011 Sep;165(3):352-62. doi: 10.1111/j.1365-2249.2011.04431.x. Epub 2011 Jun 17.


NKp44, a novel triggering surface molecule specifically expressed by activated natural killer cells, is involved in non-major histocompatibility complex-restricted tumor cell lysis.

Vitale M, Bottino C, Sivori S, Sanseverino L, Castriconi R, Marcenaro E, Augugliaro R, Moretta L, Moretta A.

J Exp Med. 1998 Jun 15;187(12):2065-72.


Low NKp30, NKp46 and NKG2D expression and reduced cytotoxic activity on NK cells in cervical cancer and precursor lesions.

Garcia-Iglesias T, Del Toro-Arreola A, Albarran-Somoza B, Del Toro-Arreola S, Sanchez-Hernandez PE, Ramirez-Dueñas MG, Balderas-Peña LM, Bravo-Cuellar A, Ortiz-Lazareno PC, Daneri-Navarro A.

BMC Cancer. 2009 Jun 16;9:186. doi: 10.1186/1471-2407-9-186.


Successfully treated HIV-infected patients have differential expression of NK cell receptors (NKp46 and NKp30) according to AIDS status at presentation.

Bisio F, Bozzano F, Marras F, Di Biagio A, Moretta L, De Maria A.

Immunol Lett. 2013 Apr;152(1):16-24. doi: 10.1016/j.imlet.2013.03.003. Epub 2013 Mar 26.


A novel ligand on astrocytes interacts with natural cytotoxicity receptor NKp44 regulating immune response mediated by NK cells.

Bowen KE, Mathew SO, Borgmann K, Ghorpade A, Mathew PA.

PLoS One. 2018 Feb 15;13(2):e0193008. doi: 10.1371/journal.pone.0193008. eCollection 2018.


Effect of recombinant cytokines on the expression of natural killer cell receptors from patients with TB or/and HIV infection.

Parasa VR, Sikhamani R, Raja A.

PLoS One. 2012;7(6):e37448. doi: 10.1371/journal.pone.0037448. Epub 2012 Jun 8.


Increased expressions of NKp44, NKp46 on NK/NKT-like cells are associated with impaired cytolytic function in self-limiting hepatitis E infection.

Das R, Tripathy A.

Med Microbiol Immunol. 2014 Oct;203(5):303-14. doi: 10.1007/s00430-014-0338-1. Epub 2014 May 14.


Molecular analysis of the methylprednisolone-mediated inhibition of NK-cell function: evidence for different susceptibility of IL-2- versus IL-15-activated NK cells.

Chiossone L, Vitale C, Cottalasso F, Moretti S, Azzarone B, Moretta L, Mingari MC.

Blood. 2007 May 1;109(9):3767-75. Epub 2007 Jan 18.

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