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IRE1α dissociates with BiP and inhibits ER stress-mediated apoptosis in cartilage development.

Han X, Zhou J, Zhang P, Song F, Jiang R, Li M, Xia F, Guo FJ.

Cell Signal. 2013 Nov;25(11):2136-46. doi: 10.1016/j.cellsig.2013.06.011. Epub 2013 Jun 29.


ATF6 upregulates XBP1S and inhibits ER stress-mediated apoptosis in osteoarthritis cartilage.

Guo FJ, Xiong Z, Lu X, Ye M, Han X, Jiang R.

Cell Signal. 2014 Feb;26(2):332-42. doi: 10.1016/j.cellsig.2013.11.018. Epub 2013 Nov 21.


Different Roles of GRP78 on Cell Proliferation and Apoptosis in Cartilage Development.

Xiong Z, Jiang R, Li X, Liu Y, Guo F.

Int J Mol Sci. 2015 Sep 7;16(9):21153-76. doi: 10.3390/ijms160921153.


Explore on the effect of ATF6 on cell growth and apoptosis in cartilage development.

Han X, Zhang P, Jiang R, Xia F, Li M, Guo FJ.

Histochem Cell Biol. 2014 Nov;142(5):497-509. doi: 10.1007/s00418-014-1233-y. Epub 2014 Jun 17.


Regulation of chondrocyte differentiation by IRE1α depends on its enzymatic activity.

Guo FJ, Jiang R, Li X, Zhang P, Han X, Liu C.

Cell Signal. 2014 Sep;26(9):1998-2007. doi: 10.1016/j.cellsig.2014.05.008. Epub 2014 May 23.


Gene regulatory network of unfolded protein response genes in endoplasmic reticulum stress.

Takayanagi S, Fukuda R, Takeuchi Y, Tsukada S, Yoshida K.

Cell Stress Chaperones. 2013 Jan;18(1):11-23. doi: 10.1007/s12192-012-0351-5. Epub 2012 Jul 18.


Endoplasmic reticulum stress signaling is involved in mitomycin C (MMC)-induced apoptosis in human fibroblasts via PERK pathway.

Shi K, Wang D, Cao X, Ge Y.

PLoS One. 2013;8(3):e59330. doi: 10.1371/journal.pone.0059330. Epub 2013 Mar 22.


IRE1a constitutes a negative feedback loop with BMP2 and acts as a novel mediator in modulating osteogenic differentiation.

Guo FJ, Jiang R, Xiong Z, Xia F, Li M, Chen L, Liu CJ.

Cell Death Dis. 2014 May 22;5:e1239. doi: 10.1038/cddis.2014.194. Erratum in: Cell Death Dis. 2015;6:e1722.


Testicular hyperthermia induces Unfolded Protein Response signaling activation in spermatocyte.

Kim JH, Park SJ, Kim TS, Park HJ, Park J, Kim BK, Kim GR, Kim JM, Huang SM, Chae JI, Park CK, Lee DS.

Biochem Biophys Res Commun. 2013 May 17;434(4):861-6. doi: 10.1016/j.bbrc.2013.04.032. Epub 2013 Apr 20.


Bushen Zhuangjin decoction inhibits TM-induced chondrocyte apoptosis mediated by endoplasmic reticulum stress.

Lin P, Weng X, Liu F, Ma Y, Chen H, Shao X, Zheng W, Liu X, Ye H, Li X.

Int J Mol Med. 2015 Dec;36(6):1519-28. doi: 10.3892/ijmm.2015.2387. Epub 2015 Oct 22.


Sustained IRE1 and ATF6 signaling is important for survival of melanoma cells undergoing ER stress.

Tay KH, Luan Q, Croft A, Jiang CC, Jin L, Zhang XD, Tseng HY.

Cell Signal. 2014 Feb;26(2):287-94. doi: 10.1016/j.cellsig.2013.11.008. Epub 2013 Nov 12.


Endoplasmic reticulum stress-mediated apoptotic pathway is involved in corpus luteum regression in rats.

Yang Y, Sun M, Shan Y, Zheng X, Ma H, Ma W, Wang Z, Pei X, Wang Y.

Reprod Sci. 2015 May;22(5):572-84. doi: 10.1177/1933719114553445. Epub 2014 Oct 20.


Experimental approaches for elucidation of stress-sensing mechanisms of the IRE1 family proteins.

Oikawa D, Kimata Y.

Methods Enzymol. 2011;490:195-216. doi: 10.1016/B978-0-12-385114-7.00012-X.


Endoplasmic reticulum stress as a correlate of cytotoxicity in human tumor cells exposed to diindolylmethane in vitro.

Sun S, Han J, Ralph WM Jr, Chandrasekaran A, Liu K, Auborn KJ, Carter TH.

Cell Stress Chaperones. 2004 Mar;9(1):76-87.


XBP1S protects cells from ER stress-induced apoptosis through Erk1/2 signaling pathway involving CHOP.

Guo FJ, Liu Y, Zhou J, Luo S, Zhao W, Li X, Liu C.

Histochem Cell Biol. 2012 Sep;138(3):447-60. doi: 10.1007/s00418-012-0967-7. Epub 2012 Jun 6.


Study on the effect of IRE1a on cell growth and apoptosis via modulation PLK1 in ER stress response.

Li X, Zhu H, Huang H, Jiang R, Zhao W, Liu Y, Zhou J, Guo FJ.

Mol Cell Biochem. 2012 Jun;365(1-2):99-108. doi: 10.1007/s11010-012-1248-4.


RNF13, a RING finger protein, mediates endoplasmic reticulum stress-induced apoptosis through the inositol-requiring enzyme (IRE1α)/c-Jun NH2-terminal kinase pathway.

Arshad M, Ye Z, Gu X, Wong CK, Liu Y, Li D, Zhou L, Zhang Y, Bay WP, Yu VC, Li P.

J Biol Chem. 2013 Mar 22;288(12):8726-36. doi: 10.1074/jbc.M112.368829. Epub 2013 Feb 1.


Modulation of endoplasmic reticulum (ER) stress-induced autophagy by C/EBP homologous protein (CHOP) and inositol-requiring enzyme 1α (IRE1α) in human colon cancer cells.

Shimodaira Y, Takahashi S, Kinouchi Y, Endo K, Shiga H, Kakuta Y, Kuroha M, Shimosegawa T.

Biochem Biophys Res Commun. 2014 Mar 7;445(2):524-33. doi: 10.1016/j.bbrc.2014.02.054. Epub 2014 Feb 21.


The unfolded protein response is triggered following a single, unaccustomed resistance-exercise bout.

Ogborn DI, McKay BR, Crane JD, Parise G, Tarnopolsky MA.

Am J Physiol Regul Integr Comp Physiol. 2014 Sep 15;307(6):R664-9. doi: 10.1152/ajpregu.00511.2013. Epub 2014 Jul 9.


Cab45S inhibits the ER stress-induced IRE1-JNK pathway and apoptosis via GRP78/BiP.

Chen L, Xu S, Liu L, Wen X, Xu Y, Chen J, Teng J.

Cell Death Dis. 2014 May 8;5:e1219. doi: 10.1038/cddis.2014.193.

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