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Fluorescent probes for investigation of isoprenoid configuration and size discrimination by bactoprenol-utilizing enzymes.

Mostafavi AZ, Lujan DK, Erickson KM, Martinez CD, Troutman JM.

Bioorg Med Chem. 2013 Sep 1;21(17):5428-35. doi: 10.1016/j.bmc.2013.06.007. Epub 2013 Jun 15.


Chemoenzymatic synthesis of an isoprenoid phosphate tool for the analysis of complex bacterial oligosaccharide biosynthesis.

Lujan DK, Stanziale JA, Mostafavi AZ, Sharma S, Troutman JM.

Carbohydr Res. 2012 Oct 1;359:44-53. doi: 10.1016/j.carres.2012.06.014. Epub 2012 Jul 1.


Species differences in alternative substrate utilization by the antibacterial target undecaprenyl pyrophosphate synthase.

Dodbele S, Martinez CD, Troutman JM.

Biochemistry. 2014 Aug 5;53(30):5042-50. doi: 10.1021/bi500545g. Epub 2014 Jul 18.


Tuning the production of variable length, fluorescent polyisoprenoids using surfactant-controlled enzymatic synthesis.

Troutman JM, Erickson KM, Scott PM, Hazel JM, Martinez CD, Dodbele S.

Biochemistry. 2015 May 12;54(18):2817-27. doi: 10.1021/acs.biochem.5b00310. Epub 2015 Apr 29.


Synthesis and application of a fluorescent substrate analogue to study ligand interactions for undecaprenyl pyrophosphate synthase.

Chen AP, Chen YH, Liu HP, Li YC, Chen CT, Liang PH.

J Am Chem Soc. 2002 Dec 25;124(51):15217-24.


Fluorescent substrate analog for monitoring chain elongation by undecaprenyl pyrophosphate synthase in real time.

Teng KH, Chen AP, Kuo CJ, Li YC, Liu HG, Chen CT, Liang PH.

Anal Biochem. 2011 Oct 1;417(1):136-41. doi: 10.1016/j.ab.2011.05.043. Epub 2011 Jun 7.


Biophysical investigation of the mode of inhibition of tetramic acids, the allosteric inhibitors of undecaprenyl pyrophosphate synthase.

Lee LV, Granda B, Dean K, Tao J, Liu E, Zhang R, Peukert S, Wattanasin S, Xie X, Ryder NS, Tommasi R, Deng G.

Biochemistry. 2010 Jun 29;49(25):5366-76. doi: 10.1021/bi100523c.


Structures, mechanisms and inhibitors of undecaprenyl diphosphate synthase: a cis-prenyltransferase for bacterial peptidoglycan biosynthesis.

Teng KH, Liang PH.

Bioorg Chem. 2012 Aug;43:51-7. doi: 10.1016/j.bioorg.2011.09.004. Epub 2011 Sep 21. Review.


Substrate and product specificities of cis-type undecaprenyl pyrophosphate synthase.

Chen AP, Chang SY, Lin YC, Sun YS, Chen CT, Wang AH, Liang PH.

Biochem J. 2005 Feb 15;386(Pt 1):169-76.


Discovery and structural characterization of an allosteric inhibitor of bacterial cis-prenyltransferase.

Danley DE, Baima ET, Mansour M, Fennell KF, Chrunyk BA, Mueller JP, Liu S, Qiu X.

Protein Sci. 2015 Jan;24(1):20-6. doi: 10.1002/pro.2579. Epub 2014 Nov 6.


Synthetic isoprenoid analogues for the study of prenylated proteins: Fluorescent imaging and proteomic applications.

Wang YC, Distefano MD.

Bioorg Chem. 2016 Feb;64:59-65. doi: 10.1016/j.bioorg.2015.12.003. Epub 2015 Dec 10. Review.


Development of a multicomponent kinetic assay of the early enzymes in the Campylobacter jejuni N-linked glycosylation pathway.

Morrison JP, Troutman JM, Imperiali B.

Bioorg Med Chem. 2010 Dec 1;18(23):8167-71. doi: 10.1016/j.bmc.2010.10.020. Epub 2010 Oct 29.


Mechanism of cis-prenyltransferase reaction probed by substrate analogues.

Lu YP, Liu HG, Teng KH, Liang PH.

Biochem Biophys Res Commun. 2010 Oct 1;400(4):758-62. doi: 10.1016/j.bbrc.2010.09.001. Epub 2010 Sep 7.


IspG converts an epoxide substrate analogue to (E)-4-hydroxy-3-methylbut-2-enyl diphosphate: implications for IspG catalysis in isoprenoid biosynthesis.

Nyland RL 2nd, Xiao Y, Liu P, Freel Meyers CL.

J Am Chem Soc. 2009 Dec 16;131(49):17734-5. doi: 10.1021/ja907470n.


Undecaprenyl diphosphate synthase, a cis-prenyltransferase synthesizing lipid carrier for bacterial cell wall biosynthesis.

Teng KH, Liang PH.

Mol Membr Biol. 2012 Nov;29(7):267-73. doi: 10.3109/09687688.2012.674162. Epub 2012 Apr 4. Review.


Simultaneous Site-Specific Dual Protein Labeling Using Protein Prenyltransferases.

Zhang Y, Blanden MJ, Sudheer Ch, Gangopadhyay SA, Rashidian M, Hougland JL, Distefano MD.

Bioconjug Chem. 2015 Dec 16;26(12):2542-53. doi: 10.1021/acs.bioconjchem.5b00553. Epub 2015 Dec 4.


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