Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 85

1.

PPARα and fatty acid oxidation mediate glucocorticoid resistance in chronic lymphocytic leukemia.

Tung S, Shi Y, Wong K, Zhu F, Gorczynski R, Laister RC, Minden M, Blechert AK, Genzel Y, Reichl U, Spaner DE.

Blood. 2013 Aug 8;122(6):969-80. doi: 10.1182/blood-2013-03-489468. Epub 2013 Jun 27.

2.

A Selective Novel Peroxisome Proliferator-Activated Receptor (PPAR)-α Antagonist Induces Apoptosis and Inhibits Proliferation of CLL Cells In Vitro and In Vivo.

Messmer D, Lorrain K, Stebbins K, Bravo Y, Stock N, Cabrera G, Correa L, Chen A, Jacintho J, Chiorazzi N, Yan XJ, Spaner D, Prasit P, Lorrain D.

Mol Med. 2015 Jun 9;21:410-9. doi: 10.2119/molmed.2015.00139.

3.

PPAR-alpha is a therapeutic target for chronic lymphocytic leukemia.

Spaner DE, Lee E, Shi Y, Wen F, Li Y, Tung S, McCaw L, Wong K, Gary-Gouy H, Dalloul A, Ceddia R, Gorzcynski R.

Leukemia. 2013 Apr;27(5):1090-9. doi: 10.1038/leu.2012.329. Epub 2012 Nov 19.

PMID:
23160450
4.

Glucocorticoid resistance in chronic lymphocytic leukaemia is associated with a failure of upregulated Bim/Bcl-2 complexes to activate Bax and Bak.

Melarangi T, Zhuang J, Lin K, Rockliffe N, Bosanquet AG, Oates M, Slupsky JR, Pettitt AR.

Cell Death Dis. 2012 Aug 16;3:e372. doi: 10.1038/cddis.2012.102.

5.

The interplay of prolactin and the glucocorticoids in the regulation of beta-cell gene expression, fatty acid oxidation, and glucose-stimulated insulin secretion: implications for carbohydrate metabolism in pregnancy.

Arumugam R, Horowitz E, Lu D, Collier JJ, Ronnebaum S, Fleenor D, Freemark M.

Endocrinology. 2008 Nov;149(11):5401-14. doi: 10.1210/en.2008-0051. Epub 2008 Jul 3.

6.

Activation of peroxisome proliferator-activated receptor-α enhances fatty acid oxidation in human adipocytes.

Lee JY, Hashizaki H, Goto T, Sakamoto T, Takahashi N, Kawada T.

Biochem Biophys Res Commun. 2011 Apr 22;407(4):818-22. doi: 10.1016/j.bbrc.2011.03.106. Epub 2011 Apr 2.

PMID:
21443859
7.

Inhibition of Lck enhances glucocorticoid sensitivity and apoptosis in lymphoid cell lines and in chronic lymphocytic leukemia.

Harr MW, Caimi PF, McColl KS, Zhong F, Patel SN, Barr PM, Distelhorst CW.

Cell Death Differ. 2010 Sep;17(9):1381-91. doi: 10.1038/cdd.2010.25. Epub 2010 Mar 19.

8.

Dexamethasone facilitates lipid accumulation and mild feed restriction improves fatty acids oxidation in skeletal muscle of broiler chicks (Gallus gallus domesticus).

Wang X, Lin H, Song Z, Jiao H.

Comp Biochem Physiol C Toxicol Pharmacol. 2010 May;151(4):447-54. doi: 10.1016/j.cbpc.2010.01.010. Epub 2010 Feb 4.

PMID:
20138241
9.

Propionate Promotes Fatty Acid Oxidation through the Up-Regulation of Peroxisome Proliferator-Activated Receptor α in Intestinal Epithelial Cells.

Higashimura Y, Naito Y, Takagi T, Uchiyama K, Mizushima K, Yoshikawa T.

J Nutr Sci Vitaminol (Tokyo). 2015;61(6):511-5. doi: 10.3177/jnsv.61.511.

10.

CD47 agonist peptides induce programmed cell death in refractory chronic lymphocytic leukemia B cells via PLCγ1 activation: evidence from mice and humans.

Martinez-Torres AC, Quiney C, Attout T, Boullet H, Herbi L, Vela L, Barbier S, Chateau D, Chapiro E, Nguyen-Khac F, Davi F, Le Garff-Tavernier M, Moumné R, Sarfati M, Karoyan P, Merle-Béral H, Launay P, Susin SA.

PLoS Med. 2015 Mar 3;12(3):e1001796. doi: 10.1371/journal.pmed.1001796. eCollection 2015 Mar.

11.

A functional, genome-wide evaluation of liposensitive yeast identifies the "ARE2 required for viability" (ARV1) gene product as a major component of eukaryotic fatty acid resistance.

Ruggles KV, Garbarino J, Liu Y, Moon J, Schneider K, Henneberry A, Billheimer J, Millar JS, Marchadier D, Valasek MA, Joblin-Mills A, Gulati S, Munkacsi AB, Repa JJ, Rader D, Sturley SL.

J Biol Chem. 2014 Feb 14;289(7):4417-31. doi: 10.1074/jbc.M113.515197. Epub 2013 Nov 22.

12.

The PPARβ/δ activator GW501516 prevents the down-regulation of AMPK caused by a high-fat diet in liver and amplifies the PGC-1α-Lipin 1-PPARα pathway leading to increased fatty acid oxidation.

Barroso E, Rodríguez-Calvo R, Serrano-Marco L, Astudillo AM, Balsinde J, Palomer X, Vázquez-Carrera M.

Endocrinology. 2011 May;152(5):1848-59. doi: 10.1210/en.2010-1468. Epub 2011 Mar 1.

PMID:
21363937
13.

Peroxisome proliferator-activated receptor-alpha contributes to the anti-inflammatory activity of glucocorticoids.

Cuzzocrea S, Bruscoli S, Mazzon E, Crisafulli C, Donato V, Di Paola R, Velardi E, Esposito E, Nocentini G, Riccardi C.

Mol Pharmacol. 2008 Feb;73(2):323-37. Epub 2007 Nov 5.

14.

Janus and PI3-kinases mediate glucocorticoid resistance in activated chronic leukemia cells.

Oppermann S, Lam AJ, Tung S, Shi Y, McCaw L, Wang G, Ylanko J, Leber B, Andrews D, Spaner DE.

Oncotarget. 2016 Nov 8;7(45):72608-72621. doi: 10.18632/oncotarget.11618.

15.

Thiazolidinedione effects on glucocorticoid receptor-mediated gene transcription and differentiation in osteoblastic cells.

Johnson TE, Vogel R, Rutledge SJ, Rodan G, Schmidt A.

Endocrinology. 1999 Jul;140(7):3245-54.

PMID:
10385421
17.

Effective elimination of chronic lymphocytic leukemia cells in the stromal microenvironment by a novel drug combination strategy using redox-mediated mechanisms.

Zhang W, Pelicano H, Yin R, Zeng J, Wen T, Ding L, Huang R.

Mol Med Rep. 2015 Nov;12(5):7374-88. doi: 10.3892/mmr.2015.4364. Epub 2015 Sep 25.

18.

A potential link between muscle peroxisome proliferator- activated receptor-alpha signaling and obesity-related diabetes.

Finck BN, Bernal-Mizrachi C, Han DH, Coleman T, Sambandam N, LaRiviere LL, Holloszy JO, Semenkovich CF, Kelly DP.

Cell Metab. 2005 Feb;1(2):133-44.

19.

Farnesyltransferase inhibitor BMS-214662 induces apoptosis in B-cell chronic lymphocytic leukemia cells.

Marzo I, Pérez-Galán P, Giraldo P, López-Royuela N, Gómez-Benito M, Larrad L, Lasierra P, Rubio-Félix D, Anel A, Naval J.

Leukemia. 2004 Oct;18(10):1599-604.

PMID:
15356656
20.

Toona sinensis leaf extract inhibits lipid accumulation through up-regulation of genes involved in lipolysis and fatty acid oxidation in adipocytes.

Liu HW, Tsai YT, Chang SJ.

J Agric Food Chem. 2014 Jun 25;62(25):5887-96. doi: 10.1021/jf500714c. Epub 2014 Jun 11.

PMID:
24884355

Supplemental Content

Support Center