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Items: 1 to 20 of 112

1.

Signaling through hepatocellular A2B adenosine receptors dampens ischemia and reperfusion injury of the liver.

Zimmerman MA, Grenz A, Tak E, Kaplan M, Ridyard D, Brodsky KS, Mandell MS, Kam I, Eltzschig HK.

Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):12012-7. doi: 10.1073/pnas.1221733110.

2.

Adora2b signaling on bone marrow derived cells dampens myocardial ischemia-reperfusion injury.

Koeppen M, Harter PN, Bonney S, Bonney M, Reithel S, Zachskorn C, Mittelbronn M, Eckle T.

Anesthesiology. 2012 Jun;116(6):1245-57. doi: 10.1097/ALN.0b013e318255793c.

3.

Differential Tissue-Specific Function of Adora2b in Cardioprotection.

Seo SW, Koeppen M, Bonney S, Gobel M, Thayer M, Harter PN, Ravid K, Eltzschig HK, Mittelbronn M, Walker L, Eckle T.

J Immunol. 2015 Aug 15;195(4):1732-43. doi: 10.4049/jimmunol.1402288.

4.

In vivo hypoxic preconditioning protects from warm liver ischemia-reperfusion injury through the adenosine A2B receptor.

Choukèr A, Ohta A, Martignoni A, Lukashev D, Zacharia LC, Jackson EK, Schnermann J, Ward JM, Kaufmann I, Klaunberg B, Sitkovsky MV, Thiel M.

Transplantation. 2012 Nov 15;94(9):894-902. doi: 10.1097/TP.0b013e31826a9a46.

5.

Crosstalk between the equilibrative nucleoside transporter ENT2 and alveolar Adora2b adenosine receptors dampens acute lung injury.

Eckle T, Hughes K, Ehrentraut H, Brodsky KS, Rosenberger P, Choi DS, Ravid K, Weng T, Xia Y, Blackburn MR, Eltzschig HK.

FASEB J. 2013 Aug;27(8):3078-89. doi: 10.1096/fj.13-228551.

6.

Cutting Edge: A2B Adenosine receptor signaling provides potent protection during intestinal ischemia/reperfusion injury.

Hart ML, Jacobi B, Schittenhelm J, Henn M, Eltzschig HK.

J Immunol. 2009 Apr 1;182(7):3965-8. doi: 10.4049/jimmunol.0802193.

7.

Alveolar Epithelial A2B Adenosine Receptors in Pulmonary Protection during Acute Lung Injury.

Hoegl S, Brodsky KS, Blackburn MR, Karmouty-Quintana H, Zwissler B, Eltzschig HK.

J Immunol. 2015 Aug 15;195(4):1815-24. doi: 10.4049/jimmunol.1401957.

8.

Adora2b adenosine receptor signaling protects during acute kidney injury via inhibition of neutrophil-dependent TNF-α release.

Grenz A, Kim JH, Bauerle JD, Tak E, Eltzschig HK, Clambey ET.

J Immunol. 2012 Nov 1;189(9):4566-73. doi: 10.4049/jimmunol.1201651.

9.

CD73-dependent generation of adenosine and endothelial Adora2b signaling attenuate diabetic nephropathy.

Tak E, Ridyard D, Kim JH, Zimmerman M, Werner T, Wang XX, Shabeka U, Seo SW, Christians U, Klawitter J, Moldovan R, Garcia G, Levi M, Haase V, Ravid K, Eltzschig HK, Grenz A.

J Am Soc Nephrol. 2014 Mar;25(3):547-63. doi: 10.1681/ASN.2012101014.

10.

Equilibrative nucleoside transporter (ENT)-1-dependent elevation of extracellular adenosine protects the liver during ischemia and reperfusion.

Zimmerman MA, Tak E, Ehrentraut SF, Kaplan M, Giebler A, Weng T, Choi DS, Blackburn MR, Kam I, Eltzschig HK, Grenz A.

Hepatology. 2013 Nov;58(5):1766-78. doi: 10.1002/hep.26505.

11.

Elevated ecto-5'-nucleotidase-mediated increased renal adenosine signaling via A2B adenosine receptor contributes to chronic hypertension.

Zhang W, Zhang Y, Wang W, Dai Y, Ning C, Luo R, Sun K, Glover L, Grenz A, Sun H, Tao L, Zhang W, Colgan SP, Blackburn MR, Eltzschig HK, Kellems RE, Xia Y.

Circ Res. 2013 May 24;112(11):1466-78. doi: 10.1161/CIRCRESAHA.111.300166.

12.

Tissue-derived proinflammatory effect of adenosine A2B receptor in lung ischemia-reperfusion injury.

Anvari F, Sharma AK, Fernandez LG, Hranjec T, Ravid K, Kron IL, Laubach VE.

J Thorac Cardiovasc Surg. 2010 Oct;140(4):871-7. doi: 10.1016/j.jtcvs.2010.06.051.

13.

Transplantation: ADORA2B helps to block liver injury.

Smith K.

Nat Rev Gastroenterol Hepatol. 2013 Aug;10(8):444. doi: 10.1038/nrgastro.2013.129. No abstract available.

PMID:
23856893
14.

Epithelial-specific A2B adenosine receptor signaling protects the colonic epithelial barrier during acute colitis.

Aherne CM, Saeedi B, Collins CB, Masterson JC, McNamee EN, Perrenoud L, Rapp CR, Curtis VF, Bayless A, Fletcher A, Glover LE, Evans CM, Jedlicka P, Furuta GT, de Zoeten EF, Colgan SP, Eltzschig HK.

Mucosal Immunol. 2015 Nov;8(6):1324-38. doi: 10.1038/mi.2015.22. Erratum in: Mucosal Immunol. 2015 May;8(3):699.

15.

Receptor activator of nuclear factor-κB ligand (RANKL) protects against hepatic ischemia/reperfusion injury in mice.

Sakai N, Van Sweringen HL, Schuster R, Blanchard J, Burns JM, Tevar AD, Edwards MJ, Lentsch AB.

Hepatology. 2012 Mar;55(3):888-97. doi: 10.1002/hep.24756.

16.

Attenuating myocardial ischemia by targeting A2B adenosine receptors.

Eltzschig HK, Bonney SK, Eckle T.

Trends Mol Med. 2013 Jun;19(6):345-54. doi: 10.1016/j.molmed.2013.02.005. Review.

17.

Identification of hypoxia-inducible factor HIF-1A as transcriptional regulator of the A2B adenosine receptor during acute lung injury.

Eckle T, Kewley EM, Brodsky KS, Tak E, Bonney S, Gobel M, Anderson D, Glover LE, Riegel AK, Colgan SP, Eltzschig HK.

J Immunol. 2014 Feb 1;192(3):1249-56. doi: 10.4049/jimmunol.1100593.

18.

Wnt-β-catenin signaling protects against hepatic ischemia and reperfusion injury in mice.

Lehwald N, Tao GZ, Jang KY, Sorkin M, Knoefel WT, Sylvester KG.

Gastroenterology. 2011 Aug;141(2):707-18, 718.e1-5. doi: 10.1053/j.gastro.2011.04.051.

19.

Endogenous danger signals trigger hepatic ischemia/reperfusion injury through toll-like receptor 4/nuclear factor-kappa B pathway.

Wang H, Li ZY, Wu HS, Wang Y, Jiang CF, Zheng QC, Zhang JX.

Chin Med J (Engl). 2007 Mar 20;120(6):509-14.

PMID:
17439747
20.

Inhibition of neogenin dampens hepatic ischemia-reperfusion injury.

Schlegel M, Granja T, Kaiser S, Körner A, Henes J, König K, Straub A, Rosenberger P, Mirakaj V.

Crit Care Med. 2014 Sep;42(9):e610-9. doi: 10.1097/CCM.0000000000000485.

PMID:
25029243
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