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KLF8 and FAK cooperatively enrich the active MMP14 on the cell surface required for the metastatic progression of breast cancer.

Lu H, Hu L, Yu L, Wang X, Urvalek AM, Li T, Shen C, Mukherjee D, Lahiri SK, Wason MS, Zhao J.

Oncogene. 2014 May 29;33(22):2909-17. doi: 10.1038/onc.2013.247. Epub 2013 Jul 1.


Identification of epithelial stromal interaction 1 as a novel effector downstream of Krüppel-like factor 8 in breast cancer invasion and metastasis.

Li T, Lu H, Shen C, Lahiri SK, Wason MS, Mukherjee D, Yu L, Zhao J.

Oncogene. 2014 Sep 25;33(39):4746-55. doi: 10.1038/onc.2013.415. Epub 2013 Oct 7.


KLF8 promotes human breast cancer cell invasion and metastasis by transcriptional activation of MMP9.

Wang X, Lu H, Urvalek AM, Li T, Yu L, Lamar J, DiPersio CM, Feustel PJ, Zhao J.

Oncogene. 2011 Apr 21;30(16):1901-11. doi: 10.1038/onc.2010.563. Epub 2010 Dec 13.


Activation of KLF8 transcription by focal adhesion kinase in human ovarian epithelial and cancer cells.

Wang X, Urvalek AM, Liu J, Zhao J.

J Biol Chem. 2008 May 16;283(20):13934-42. doi: 10.1074/jbc.M709300200. Epub 2008 Mar 19.


KLF8 promotes tumorigenesis, invasion and metastasis of colorectal cancer cells by transcriptional activation of FHL2.

Yan Q, Zhang W, Wu Y, Wu M, Zhang M, Shi X, Zhao J, Nan Q, Chen Y, Wang L, Cheng T, Li J, Bai Y, Liu S, Wang J.

Oncotarget. 2015 Sep 22;6(28):25402-17. doi: 10.18632/oncotarget.4517.


Krüppel-like factor 8 induces epithelial to mesenchymal transition and epithelial cell invasion.

Wang X, Zheng M, Liu G, Xia W, McKeown-Longo PJ, Hung MC, Zhao J.

Cancer Res. 2007 Aug 1;67(15):7184-93.


p63 drives invasion in keratinocytes expressing HPV16 E6/E7 genes through regulation of Src-FAK signalling.

Srivastava K, Pickard A, McDade S, McCance DJ.

Oncotarget. 2017 Mar 7;8(10):16202-16219. doi: 10.18632/oncotarget.3892.


NEDD9 depletion leads to MMP14 inactivation by TIMP2 and prevents invasion and metastasis.

McLaughlin SL, Ice RJ, Rajulapati A, Kozyulina PY, Livengood RH, Kozyreva VK, Loskutov YV, Culp MV, Weed SA, Ivanov AV, Pugacheva EN.

Mol Cancer Res. 2014 Jan;12(1):69-81. doi: 10.1158/1541-7786.MCR-13-0300. Epub 2013 Nov 7.


Krüppel-like factor 8 activates the transcription of C-X-C cytokine receptor type 4 to promote breast cancer cell invasion, transendothelial migration and metastasis.

Mukherjee D, Lu H, Yu L, He C, Lahiri SK, Li T, Zhao J.

Oncotarget. 2016 Apr 26;7(17):23552-68. doi: 10.18632/oncotarget.8083.


A novel role of Krüppel-like factor 8 in DNA repair in breast cancer cells.

Lu H, Hu L, Li T, Lahiri S, Shen C, Wason MS, Mukherjee D, Xie H, Yu L, Zhao J.

J Biol Chem. 2012 Dec 21;287(52):43720-9. doi: 10.1074/jbc.M112.418053. Epub 2012 Oct 26.


Krüppel-like factor 8 involved in hypoxia promotes the invasion and metastasis of gastric cancer via epithelial to mesenchymal transition.

Liu N, Wang Y, Zhou Y, Pang H, Zhou J, Qian P, Liu L, Zhang H.

Oncol Rep. 2014 Dec;32(6):2397-404. doi: 10.3892/or.2014.3495. Epub 2014 Sep 18.


NEDD9/Arf6-dependent endocytic trafficking of matrix metalloproteinase 14: a novel mechanism for blocking mesenchymal cell invasion and metastasis of breast cancer.

Loskutov YV, Kozyulina PY, Kozyreva VK, Ice RJ, Jones BC, Roston TJ, Smolkin MB, Ivanov AV, Wysolmerski RB, Pugacheva EN.

Oncogene. 2015 Jul;34(28):3662-75. doi: 10.1038/onc.2014.297. Epub 2014 Sep 22.


Krüppel‑like factor expression and correlation with FAK, MMP‑9 and E‑cadherin expression in hepatocellular carcinoma.

Han S, Han L, Sun H, Zan X, Zhou Z, Xu K, Yao Y, Liu Q.

Mol Med Rep. 2013 Jul;8(1):81-8. doi: 10.3892/mmr.2013.1471. Epub 2013 May 10.


Function of focal adhesion kinase scaffolding to mediate endophilin A2 phosphorylation promotes epithelial-mesenchymal transition and mammary cancer stem cell activities in vivo.

Fan H, Zhao X, Sun S, Luo M, Guan JL.

J Biol Chem. 2013 Feb 1;288(5):3322-33. doi: 10.1074/jbc.M112.420497. Epub 2012 Dec 19.


Matrix Metalloproteinase 14 promotes lung cancer by cleavage of Heparin-Binding EGF-like Growth Factor.

Stawowczyk M, Wellenstein MD, Lee SB, Yomtoubian S, Durrans A, Choi H, Narula N, Altorki NK, Gao D, Mittal V.

Neoplasia. 2017 Feb;19(2):55-64. doi: 10.1016/j.neo.2016.11.005. Epub 2016 Dec 23.


Growth-arrest-specific 7C protein inhibits tumor metastasis via the N-WASP/FAK/F-actin and hnRNP U/β-TrCP/β-catenin pathways in lung cancer.

Tseng RC, Chang JW, Mao JS, Tsai CD, Wu PC, Lin CJ, Lu YL, Liao SY, Cheng HC, Hsu HS, Wang YC.

Oncotarget. 2015 Dec 29;6(42):44207-21. doi: 10.18632/oncotarget.6229.


KLF8 involves in TGF-beta-induced EMT and promotes invasion and migration in gastric cancer cells.

Zhang H, Liu L, Wang Y, Zhao G, Xie R, Liu C, Xiao X, Wu K, Nie Y, Zhang H, Fan D.

J Cancer Res Clin Oncol. 2013 Jun;139(6):1033-42. doi: 10.1007/s00432-012-1363-3. Epub 2013 Mar 16.


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