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Items: 1 to 20 of 148

1.

Critical tumor suppressor function mediated by epithelial Mig-6 in endometrial cancer.

Kim TH, Lee DK, Cho SN, Orvis GD, Behringer RR, Lydon JP, Ku BJ, McCampbell AS, Broaddus RR, Jeong JW.

Cancer Res. 2013 Aug 15;73(16):5090-9. doi: 10.1158/0008-5472.CAN-13-0241. Epub 2013 Jun 27.

2.

Mig-6 modulates uterine steroid hormone responsiveness and exhibits altered expression in endometrial disease.

Jeong JW, Lee HS, Lee KY, White LD, Broaddus RR, Zhang YW, Vande Woude GF, Giudice LC, Young SL, Lessey BA, Tsai SY, Lydon JP, DeMayo FJ.

Proc Natl Acad Sci U S A. 2009 May 26;106(21):8677-82. doi: 10.1073/pnas.0903632106. Epub 2009 May 13.

3.

Epithelial progesterone receptor exhibits pleiotropic roles in uterine development and function.

Franco HL, Rubel CA, Large MJ, Wetendorf M, Fernandez-Valdivia R, Jeong JW, Spencer TE, Behringer RR, Lydon JP, Demayo FJ.

FASEB J. 2012 Mar;26(3):1218-27. doi: 10.1096/fj.11-193334. Epub 2011 Dec 12.

4.

The synergistic effect of Mig-6 and Pten ablation on endometrial cancer development and progression.

Kim TH, Franco HL, Jung SY, Qin J, Broaddus RR, Lydon JP, Jeong JW.

Oncogene. 2010 Jul 1;29(26):3770-80. doi: 10.1038/onc.2010.126. Epub 2010 Apr 26.

5.

Mig-6 Mouse Model of Endometrial Cancer.

Kim TH, Yoo JY, Jeong JW.

Adv Exp Med Biol. 2017;943:243-259.

PMID:
27910070
6.

Mig-6 suppresses endometrial cancer associated with Pten deficiency and ERK activation.

Kim TH, Yoo JY, Kim HI, Gilbert J, Ku BJ, Li J, Mills GB, Broaddus RR, Lydon JP, Lim JM, Yoon HG, Jeong JW.

Cancer Res. 2014 Dec 15;74(24):7371-82. doi: 10.1158/0008-5472.CAN-14-0794. Epub 2014 Nov 6.

7.

Altered AIB1 or AIB1Δ3 expression impacts ERα effects on mammary gland stromal and epithelial content.

Nakles RE, Shiffert MT, Díaz-Cruz ES, Cabrera MC, Alotaiby M, Miermont AM, Riegel AT, Furth PA.

Mol Endocrinol. 2011 Apr;25(4):549-63. doi: 10.1210/me.2010-0114. Epub 2011 Feb 3.

8.

Mig-6 regulates endometrial genes involved in cell cycle and progesterone signaling.

Yoo JY, Kim TH, Lee JH, Dunwoodie SL, Ku BJ, Jeong JW.

Biochem Biophys Res Commun. 2015 Jul 10;462(4):409-14. doi: 10.1016/j.bbrc.2015.04.146. Epub 2015 May 12.

9.

MIG-6 negatively regulates STAT3 phosphorylation in uterine epithelial cells.

Yoo JY, Yang WS, Lee JH, Kim BG, Broaddus RR, Lim JM, Kim TH, Jeong JW.

Oncogene. 2017 Sep 18. doi: 10.1038/onc.2017.335. [Epub ahead of print]

PMID:
28925396
10.

Regulation of progesterone receptors and decidualization in uterine stroma of the estrogen receptor-alpha knockout mouse.

Kurita T, Lee K, Saunders PT, Cooke PS, Taylor JA, Lubahn DB, Zhao C, Mäkelä S, Gustafsson JA, Dahiya R, Cunha GR.

Biol Reprod. 2001 Jan;64(1):272-83.

PMID:
11133684
11.

Steroid hormone intervenes in the endometrial tumorigenesis of pten ablation.

Kim HI, Kim TH, Lim JM, Jeong JW.

J Cancer Prev. 2013 Dec;18(4):313-21.

12.

Uterine epithelial cell proliferation and endometrial hyperplasia: evidence from a mouse model.

Gao Y, Li S, Li Q.

Mol Hum Reprod. 2014 Aug;20(8):776-86. doi: 10.1093/molehr/gau033. Epub 2014 Apr 25.

13.

Uterine epithelial estrogen receptor α is dispensable for proliferation but essential for complete biological and biochemical responses.

Winuthayanon W, Hewitt SC, Orvis GD, Behringer RR, Korach KS.

Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19272-7. doi: 10.1073/pnas.1013226107. Epub 2010 Oct 25.

14.

Overexpression of progesterone receptor A isoform in mice leads to endometrial hyperproliferation, hyperplasia and atypia.

Fleisch MC, Chou YC, Cardiff RD, Asaithambi A, Shyamala G.

Mol Hum Reprod. 2009 Apr;15(4):241-9. doi: 10.1093/molehr/gap013. Epub 2009 Feb 18.

15.

The activation function-1 domain of estrogen receptor alpha in uterine stromal cells is required for mouse but not human uterine epithelial response to estrogen.

Kurita T, Medina R, Schabel AB, Young P, Gama P, Parekh TV, Brody J, Cunha GR, Osteen KG, Bruner-Tran KL, Gold LI.

Differentiation. 2005 Jul;73(6):313-22.

PMID:
16138832
16.

Endometrial tumorigenesis in Pten(+/-) mice is independent of coexistence of estrogen and estrogen receptor α.

Joshi A, Wang H, Jiang G, Douglas W, Chan JS, Korach KS, Ellenson LH.

Am J Pathol. 2012 Jun;180(6):2536-47. doi: 10.1016/j.ajpath.2012.03.006. Epub 2012 Apr 13.

17.

Epithelial-stromal interaction and progesterone receptors in the mouse uterus.

Rubel CA, Jeong JW, Tsai SY, Lydon JP, Demayo FJ.

Semin Reprod Med. 2010 Jan;28(1):27-35. doi: 10.1055/s-0029-1242990. Epub 2010 Jan 26. Review.

PMID:
20104426
18.

CTNNB1 in mesenchyme regulates epithelial cell differentiation during Müllerian duct and postnatal uterine development.

Stewart CA, Wang Y, Bonilla-Claudio M, Martin JF, Gonzalez G, Taketo MM, Behringer RR.

Mol Endocrinol. 2013 Sep;27(9):1442-54. doi: 10.1210/me.2012-1126. Epub 2013 Jul 31.

19.

Progesterone receptor signaling in the microenvironment of endometrial cancer influences its response to hormonal therapy.

Janzen DM, Rosales MA, Paik DY, Lee DS, Smith DA, Witte ON, Iruela-Arispe ML, Memarzadeh S.

Cancer Res. 2013 Aug 1;73(15):4697-710. doi: 10.1158/0008-5472.CAN-13-0930. Epub 2013 Jun 6.

20.

Stromal deletion of the APC tumor suppressor in mice triggers development of endometrial cancer.

Tanwar PS, Zhang L, Roberts DJ, Teixeira JM.

Cancer Res. 2011 Mar 1;71(5):1584-96. doi: 10.1158/0008-5472.CAN-10-3166.

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