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Items: 1 to 20 of 86

1.

Acquired expression of NFATc1 downregulates E-cadherin and promotes cancer cell invasion.

Oikawa T, Nakamura A, Onishi N, Yamada T, Matsuo K, Saya H.

Cancer Res. 2013 Aug 15;73(16):5100-9. doi: 10.1158/0008-5472.CAN-13-0274. Epub 2013 Jun 28.

2.

Inhibition of CCN6 (Wnt-1-induced signaling protein 3) down-regulates E-cadherin in the breast epithelium through induction of snail and ZEB1.

Huang W, Zhang Y, Varambally S, Chinnaiyan AM, Banerjee M, Merajver SD, Kleer CG.

Am J Pathol. 2008 Apr;172(4):893-904. doi: 10.2353/ajpath.2008.070899. Epub 2008 Mar 5.

3.

Downregulated microRNA-200a promotes EMT and tumor growth through the wnt/β-catenin pathway by targeting the E-cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma.

Cong N, Du P, Zhang A, Shen F, Su J, Pu P, Wang T, Zjang J, Kang C, Zhang Q.

Oncol Rep. 2013 Apr;29(4):1579-87. doi: 10.3892/or.2013.2267. Epub 2013 Jan 31.

PMID:
23381389
4.

Roles of STAT3 and ZEB1 proteins in E-cadherin down-regulation and human colorectal cancer epithelial-mesenchymal transition.

Xiong H, Hong J, Du W, Lin YW, Ren LL, Wang YC, Su WY, Wang JL, Cui Y, Wang ZH, Fang JY.

J Biol Chem. 2012 Feb 17;287(8):5819-32. doi: 10.1074/jbc.M111.295964. Epub 2011 Dec 28.

5.

The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2.

Park SM, Gaur AB, Lengyel E, Peter ME.

Genes Dev. 2008 Apr 1;22(7):894-907. doi: 10.1101/gad.1640608. Erratum in: Genes Dev. 2009 Jun 1;23(11):1378.

6.

E-cadherin, beta-catenin, and ZEB1 in malignant progression of cancer.

Schmalhofer O, Brabletz S, Brabletz T.

Cancer Metastasis Rev. 2009 Jun;28(1-2):151-66. doi: 10.1007/s10555-008-9179-y. Review.

PMID:
19153669
7.

The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2.

Korpal M, Lee ES, Hu G, Kang Y.

J Biol Chem. 2008 May 30;283(22):14910-4. doi: 10.1074/jbc.C800074200. Epub 2008 Apr 14.

8.

Fibroblast growth factor 2 induces E-cadherin down-regulation via PI3K/Akt/mTOR and MAPK/ERK signaling in ovarian cancer cells.

Lau MT, So WK, Leung PC.

PLoS One. 2013;8(3):e59083. doi: 10.1371/journal.pone.0059083. Epub 2013 Mar 15.

9.

Involvement of ZEB1 and E-cadherin in the invasion of lung squamous cell carcinoma.

Zhang J, Lu C, Zhang J, Kang J, Cao C, Li M.

Mol Biol Rep. 2013 Feb;40(2):949-56. doi: 10.1007/s11033-012-2136-4. Epub 2012 Oct 14.

PMID:
23065281
10.

Zeb1-mediated T-cadherin repression increases the invasive potential of gallbladder cancer.

Adachi Y, Takeuchi T, Nagayama T, Ohtsuki Y, Furihata M.

FEBS Lett. 2009 Jan 22;583(2):430-6. doi: 10.1016/j.febslet.2008.12.042. Epub 2008 Dec 29.

11.

Claudin-1 up-regulates the repressor ZEB-1 to inhibit E-cadherin expression in colon cancer cells.

Singh AB, Sharma A, Smith JJ, Krishnan M, Chen X, Eschrich S, Washington MK, Yeatman TJ, Beauchamp RD, Dhawan P.

Gastroenterology. 2011 Dec;141(6):2140-53. doi: 10.1053/j.gastro.2011.08.038. Epub 2011 Aug 28.

12.

Recruitment of histone deacetylases HDAC1 and HDAC2 by the transcriptional repressor ZEB1 downregulates E-cadherin expression in pancreatic cancer.

Aghdassi A, Sendler M, Guenther A, Mayerle J, Behn CO, Heidecke CD, Friess H, Büchler M, Evert M, Lerch MM, Weiss FU.

Gut. 2012 Mar;61(3):439-48. doi: 10.1136/gutjnl-2011-300060. Epub 2011 Dec 5.

PMID:
22147512
13.

NFATc1 activation promotes the invasion of U251 human glioblastoma multiforme cells through COX-2.

Wang L, Wang Z, Li J, Zhang W, Ren F, Yue W.

Int J Mol Med. 2015 May;35(5):1333-40. doi: 10.3892/ijmm.2015.2124. Epub 2015 Mar 4.

PMID:
25738651
14.

The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion.

Comijn J, Berx G, Vermassen P, Verschueren K, van Grunsven L, Bruyneel E, Mareel M, Huylebroeck D, van Roy F.

Mol Cell. 2001 Jun;7(6):1267-78.

15.

Targeting Integrin-Linked Kinase Suppresses Invasion and Metastasis through Downregulation of Epithelial-to-Mesenchymal Transition in Renal Cell Carcinoma.

Han KS, Li N, Raven PA, Fazli L, Ettinger S, Hong SJ, Gleave ME, So AI.

Mol Cancer Ther. 2015 Apr;14(4):1024-34. doi: 10.1158/1535-7163.MCT-14-0771. Epub 2015 Feb 5.

16.

Loss of the polycomb protein Mel-18 enhances the epithelial-mesenchymal transition by ZEB1 and ZEB2 expression through the downregulation of miR-205 in breast cancer.

Lee JY, Park MK, Park JH, Lee HJ, Shin DH, Kang Y, Lee CH, Kong G.

Oncogene. 2014 Mar 6;33(10):1325-35. doi: 10.1038/onc.2013.53. Epub 2013 Mar 11.

PMID:
23474752
17.

A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells.

Burk U, Schubert J, Wellner U, Schmalhofer O, Vincan E, Spaderna S, Brabletz T.

EMBO Rep. 2008 Jun;9(6):582-9. doi: 10.1038/embor.2008.74. Epub 2008 May 16.

18.

Downregulation of GRHL2 inhibits the proliferation of colorectal cancer cells by targeting ZEB1.

Quan Y, Jin R, Huang A, Zhao H, Feng B, Zang L, Zheng M.

Cancer Biol Ther. 2014 Jul;15(7):878-87. doi: 10.4161/cbt.28877. Epub 2014 Apr 22.

19.

Metastatic progression of prostate cancer and e-cadherin regulation by zeb1 and SRC family kinases.

Putzke AP, Ventura AP, Bailey AM, Akture C, Opoku-Ansah J, Celiktaş M, Hwang MS, Darling DS, Coleman IM, Nelson PS, Nguyen HM, Corey E, Tewari M, Morrissey C, Vessella RL, Knudsen BS.

Am J Pathol. 2011 Jul;179(1):400-10. doi: 10.1016/j.ajpath.2011.03.028. Epub 2011 May 4.

20.

MiR-150 is associated with poor prognosis in esophageal squamous cell carcinoma via targeting the EMT inducer ZEB1.

Yokobori T, Suzuki S, Tanaka N, Inose T, Sohda M, Sano A, Sakai M, Nakajima M, Miyazaki T, Kato H, Kuwano H.

Cancer Sci. 2013 Jan;104(1):48-54. doi: 10.1111/cas.12030. Epub 2012 Nov 8.

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