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Items: 1 to 20 of 126

1.

Identification of PTEN at the ER and MAMs and its regulation of Ca(2+) signaling and apoptosis in a protein phosphatase-dependent manner.

Bononi A, Bonora M, Marchi S, Missiroli S, Poletti F, Giorgi C, Pandolfi PP, Pinton P.

Cell Death Differ. 2013 Dec;20(12):1631-43. doi: 10.1038/cdd.2013.77. Epub 2013 Jun 28.

2.

Study of PTEN subcellular localization.

Bononi A, Pinton P.

Methods. 2015 May;77-78:92-103. doi: 10.1016/j.ymeth.2014.10.002. Epub 2014 Oct 13. Review.

4.

p53 at the endoplasmic reticulum regulates apoptosis in a Ca2+-dependent manner.

Giorgi C, Bonora M, Sorrentino G, Missiroli S, Poletti F, Suski JM, Galindo Ramirez F, Rizzuto R, Di Virgilio F, Zito E, Pandolfi PP, Wieckowski MR, Mammano F, Del Sal G, Pinton P.

Proc Natl Acad Sci U S A. 2015 Feb 10;112(6):1779-84. doi: 10.1073/pnas.1410723112. Epub 2015 Jan 26.

5.

PML regulates apoptosis at endoplasmic reticulum by modulating calcium release.

Giorgi C, Ito K, Lin HK, Santangelo C, Wieckowski MR, Lebiedzinska M, Bononi A, Bonora M, Duszynski J, Bernardi R, Rizzuto R, Tacchetti C, Pinton P, Pandolfi PP.

Science. 2010 Nov 26;330(6008):1247-51. doi: 10.1126/science.1189157. Epub 2010 Oct 28.

6.

The SR/ER-mitochondria calcium crosstalk is regulated by GSK3β during reperfusion injury.

Gomez L, Thiebaut PA, Paillard M, Ducreux S, Abrial M, Crola Da Silva C, Durand A, Alam MR, Van Coppenolle F, Sheu SS, Ovize M.

Cell Death Differ. 2016 Feb;23(2):313-22. doi: 10.1038/cdd.2015.101. Epub 2015 Jul 24. Erratum in: Cell Death Differ. 2015 Nov;22(11):1890.

8.

Tespa1 is a novel component of mitochondria-associated endoplasmic reticulum membranes and affects mitochondrial calcium flux.

Matsuzaki H, Fujimoto T, Tanaka M, Shirasawa S.

Biochem Biophys Res Commun. 2013 Apr 12;433(3):322-6. doi: 10.1016/j.bbrc.2013.02.099. Epub 2013 Mar 15.

PMID:
23501103
9.

PTEN protein phosphatase activity correlates with control of gene expression and invasion, a tumor-suppressing phenotype, but not with AKT activity.

Tibarewal P, Zilidis G, Spinelli L, Schurch N, Maccario H, Gray A, Perera NM, Davidson L, Barton GJ, Leslie NR.

Sci Signal. 2012 Feb 28;5(213):ra18. doi: 10.1126/scisignal.2002138.

10.

Selective modulation of subtype III IP₃R by Akt regulates ER Ca²⁺ release and apoptosis.

Marchi S, Marinello M, Bononi A, Bonora M, Giorgi C, Rimessi A, Pinton P.

Cell Death Dis. 2012 May 3;3:e304. doi: 10.1038/cddis.2012.45.

11.

Disruption of calcium transfer from ER to mitochondria links alterations of mitochondria-associated ER membrane integrity to hepatic insulin resistance.

Rieusset J, Fauconnier J, Paillard M, Belaidi E, Tubbs E, Chauvin MA, Durand A, Bravard A, Teixeira G, Bartosch B, Michelet M, Theurey P, Vial G, Demion M, Blond E, Zoulim F, Gomez L, Vidal H, Lacampagne A, Ovize M.

Diabetologia. 2016 Mar;59(3):614-23. doi: 10.1007/s00125-015-3829-8. Epub 2015 Dec 10.

PMID:
26660890
12.

Role of SERCA1 truncated isoform in the proapoptotic calcium transfer from ER to mitochondria during ER stress.

Chami M, Oulès B, Szabadkai G, Tacine R, Rizzuto R, Paterlini-Bréchot P.

Mol Cell. 2008 Dec 5;32(5):641-51. doi: 10.1016/j.molcel.2008.11.014.

13.

GM1-ganglioside accumulation at the mitochondria-associated ER membranes links ER stress to Ca(2+)-dependent mitochondrial apoptosis.

Sano R, Annunziata I, Patterson A, Moshiach S, Gomero E, Opferman J, Forte M, d'Azzo A.

Mol Cell. 2009 Nov 13;36(3):500-11. doi: 10.1016/j.molcel.2009.10.021.

14.

Mitochondria-associated membranes (MAMs) as hotspot Ca(2+) signaling units.

Bononi A, Missiroli S, Poletti F, Suski JM, Agnoletto C, Bonora M, De Marchi E, Giorgi C, Marchi S, Patergnani S, Rimessi A, Wieckowski MR, Pinton P.

Adv Exp Med Biol. 2012;740:411-37. doi: 10.1007/978-94-007-2888-2_17. Review.

PMID:
22453952
16.

New functions of mitochondria associated membranes in cellular signaling.

van Vliet AR, Verfaillie T, Agostinis P.

Biochim Biophys Acta. 2014 Oct;1843(10):2253-62. doi: 10.1016/j.bbamcr.2014.03.009. Epub 2014 Mar 15. Review.

18.

PTEN deficiency causes dyschondroplasia in mice by enhanced hypoxia-inducible factor 1alpha signaling and endoplasmic reticulum stress.

Yang G, Sun Q, Teng Y, Li F, Weng T, Yang X.

Development. 2008 Nov;135(21):3587-97. doi: 10.1242/dev.028118. Epub 2008 Oct 2.

19.

Inositol 1,4,5-trisphosphate receptor-isoform diversity in cell death and survival.

Ivanova H, Vervliet T, Missiaen L, Parys JB, De Smedt H, Bultynck G.

Biochim Biophys Acta. 2014 Oct;1843(10):2164-83. doi: 10.1016/j.bbamcr.2014.03.007. Epub 2014 Mar 15. Review.

20.

PTEN counteracts FBXL2 to promote IP3R3- and Ca2+-mediated apoptosis limiting tumour growth.

Kuchay S, Giorgi C, Simoneschi D, Pagan J, Missiroli S, Saraf A, Florens L, Washburn MP, Collazo-Lorduy A, Castillo-Martin M, Cordon-Cardo C, Sebti SM, Pinton P, Pagano M.

Nature. 2017 Jun 22;546(7659):554-558. doi: 10.1038/nature22965. Epub 2017 Jun 14.

PMID:
28614300

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