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Regulation of Tcf7l1 DNA binding and protein stability as principal mechanisms of Wnt/β-catenin signaling.

Shy BR, Wu CI, Khramtsova GF, Zhang JY, Olopade OI, Goss KH, Merrill BJ.

Cell Rep. 2013 Jul 11;4(1):1-9. doi: 10.1016/j.celrep.2013.06.001. Epub 2013 Jun 27.


Convergence of cMyc and β-catenin on Tcf7l1 enables endoderm specification.

Morrison G, Scognamiglio R, Trumpp A, Smith A.

EMBO J. 2016 Feb 1;35(3):356-68. doi: 10.15252/embj.201592116. Epub 2015 Dec 16.


Regulation of self-renewal and reprogramming by TCF factors.

Ombrato L, Lluis F, Cosma MP.

Cell Cycle. 2012 Jan 1;11(1):39-47. doi: 10.4161/cc.11.1.18759. Epub 2012 Jan 1.


Function of Wnt/β-catenin in counteracting Tcf3 repression through the Tcf3-β-catenin interaction.

Wu CI, Hoffman JA, Shy BR, Ford EM, Fuchs E, Nguyen H, Merrill BJ.

Development. 2012 Jun;139(12):2118-29. doi: 10.1242/dev.076067. Epub 2012 May 9.


Tcf7l1 proteins cell autonomously restrict cardiomyocyte and promote endothelial specification in zebrafish.

Sorrell MR, Dohn TE, D'Aniello E, Waxman JS.

Dev Biol. 2013 Aug 15;380(2):199-210. doi: 10.1016/j.ydbio.2013.05.016. Epub 2013 May 21.


Tcf7l1 prepares epiblast cells in the gastrulating mouse embryo for lineage specification.

Hoffman JA, Wu CI, Merrill BJ.

Development. 2013 Apr;140(8):1665-75. doi: 10.1242/dev.087387. Epub 2013 Mar 13.


Tcf7l1 protects the anterior neural fold from adopting the neural crest fate.

Mašek J, Machoň O, Kořínek V, Taketo MM, Kozmik Z.

Development. 2016 Jun 15;143(12):2206-16. doi: 10.1242/dev.132357.


Tcf3 represses Wnt-β-catenin signaling and maintains neural stem cell population during neocortical development.

Kuwahara A, Sakai H, Xu Y, Itoh Y, Hirabayashi Y, Gotoh Y.

PLoS One. 2014 May 15;9(5):e94408. doi: 10.1371/journal.pone.0094408. eCollection 2014.


A dynamic exchange of TCF3 and TCF4 transcription factors controls MYC expression in colorectal cancer cells.

Shah M, Rennoll SA, Raup-Konsavage WM, Yochum GS.

Cell Cycle. 2015;14(3):323-32. doi: 10.4161/15384101.2014.980643.


Tissue-specific derepression of TCF/LEF controls the activity of the Wnt/β-catenin pathway.

Lu FI, Sun YH, Wei CY, Thisse C, Thisse B.

Nat Commun. 2014 Nov 5;5:5368. doi: 10.1038/ncomms6368.


Visualization and exploration of Tcf/Lef function using a highly responsive Wnt/β-catenin signaling-reporter transgenic zebrafish.

Shimizu N, Kawakami K, Ishitani T.

Dev Biol. 2012 Oct 1;370(1):71-85. doi: 10.1016/j.ydbio.2012.07.016. Epub 2012 Jul 25.


Role of the Rap2/TNIK kinase pathway in regulation of LRP6 stability for Wnt signaling.

Park DS, Seo JH, Hong M, Choi SC.

Biochem Biophys Res Commun. 2013 Jun 28;436(2):338-43. doi: 10.1016/j.bbrc.2013.05.104. Epub 2013 Jun 4.


Kdm2a/b Lysine Demethylases Regulate Canonical Wnt Signaling by Modulating the Stability of Nuclear β-Catenin.

Lu L, Gao Y, Zhang Z, Cao Q, Zhang X, Zou J, Cao Y.

Dev Cell. 2015 Jun 22;33(6):660-74. doi: 10.1016/j.devcel.2015.04.006. Epub 2015 May 21.


Mouse Tcf3 represses canonical Wnt signaling by either competing for β-catenin binding or through occupation of DNA-binding sites.

Solberg N, Machon O, Machonova O, Krauss S.

Mol Cell Biochem. 2012 Jun;365(1-2):53-63. doi: 10.1007/s11010-012-1243-9. Epub 2012 Jan 22.


3,5,4'-Trimethoxystilbene, a natural methoxylated analog of resveratrol, inhibits breast cancer cell invasiveness by downregulation of PI3K/Akt and Wnt/β-catenin signaling cascades and reversal of epithelial-mesenchymal transition.

Tsai JH, Hsu LS, Lin CL, Hong HM, Pan MH, Way TD, Chen WJ.

Toxicol Appl Pharmacol. 2013 Nov 1;272(3):746-56. doi: 10.1016/j.taap.2013.07.019. Epub 2013 Aug 3.


Redundant expression of canonical Wnt ligands in human breast cancer cell lines.

Benhaj K, Akcali KC, Ozturk M.

Oncol Rep. 2006 Mar;15(3):701-7.


Dosage-dependent hedgehog signals integrated with Wnt/beta-catenin signaling regulate external genitalia formation as an appendicular program.

Miyagawa S, Moon A, Haraguchi R, Inoue C, Harada M, Nakahara C, Suzuki K, Matsumaru D, Kaneko T, Matsuo I, Yang L, Taketo MM, Iguchi T, Evans SM, Yamada G.

Development. 2009 Dec;136(23):3969-78. doi: 10.1242/dev.039438.


Bortezomib induces osteoblast differentiation via Wnt-independent activation of beta-catenin/TCF signaling.

Qiang YW, Hu B, Chen Y, Zhong Y, Shi B, Barlogie B, Shaughnessy JD Jr.

Blood. 2009 Apr 30;113(18):4319-30. doi: 10.1182/blood-2008-08-174300. Epub 2009 Feb 4.


Beta-catenin signaling plays a disparate role in different phases of fracture repair: implications for therapy to improve bone healing.

Chen Y, Whetstone HC, Lin AC, Nadesan P, Wei Q, Poon R, Alman BA.

PLoS Med. 2007 Jul 31;4(7):e249.


Gene regulatory networks mediating canonical Wnt signal-directed control of pluripotency and differentiation in embryo stem cells.

Zhang X, Peterson KA, Liu XS, McMahon AP, Ohba S.

Stem Cells. 2013 Dec;31(12):2667-79. doi: 10.1002/stem.1371.

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