Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 366

1.

Cystic fibrosis transmembrane conductance regulator degradation: cross-talk between the ubiquitylation and SUMOylation pathways.

Ahner A, Gong X, Frizzell RA.

FEBS J. 2013 Sep;280(18):4430-8. doi: 10.1111/febs.12415. Epub 2013 Jul 22. Review.

2.

Small heat shock proteins target mutant cystic fibrosis transmembrane conductance regulator for degradation via a small ubiquitin-like modifier-dependent pathway.

Ahner A, Gong X, Schmidt BZ, Peters KW, Rabeh WM, Thibodeau PH, Lukacs GL, Frizzell RA.

Mol Biol Cell. 2013 Jan;24(2):74-84. doi: 10.1091/mbc.E12-09-0678. Epub 2012 Nov 14.

3.

Non-native Conformers of Cystic Fibrosis Transmembrane Conductance Regulator NBD1 Are Recognized by Hsp27 and Conjugated to SUMO-2 for Degradation.

Gong X, Ahner A, Roldan A, Lukacs GL, Thibodeau PH, Frizzell RA.

J Biol Chem. 2016 Jan 22;291(4):2004-17. doi: 10.1074/jbc.M115.685628. Epub 2015 Dec 1.

4.

Divergent signaling via SUMO modification: potential for CFTR modulation.

Ahner A, Gong X, Frizzell RA.

Am J Physiol Cell Physiol. 2016 Feb 1;310(3):C175-80. doi: 10.1152/ajpcell.00124.2015. Epub 2015 Nov 18. Review.

5.

Control of cystic fibrosis transmembrane conductance regulator membrane trafficking: not just from the endoplasmic reticulum to the Golgi.

Farinha CM, Matos P, Amaral MD.

FEBS J. 2013 Sep;280(18):4396-406. doi: 10.1111/febs.12392. Epub 2013 Jul 5. Review.

6.

c-Myc is targeted to the proteasome for degradation in a SUMOylation-dependent manner, regulated by PIAS1, SENP7 and RNF4.

González-Prieto R, Cuijpers SA, Kumar R, Hendriks IA, Vertegaal AC.

Cell Cycle. 2015;14(12):1859-72. doi: 10.1080/15384101.2015.1040965.

7.

SYVN1, NEDD8, and FBXO2 Proteins Regulate ΔF508 Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Ubiquitin-mediated Proteasomal Degradation.

Ramachandran S, Osterhaus SR, Parekh KR, Jacobi AM, Behlke MA, McCray PB Jr.

J Biol Chem. 2016 Dec 2;291(49):25489-25504. Epub 2016 Oct 18.

PMID:
27756846
8.

Human heat shock protein 105/110 kDa (Hsp105/110) regulates biogenesis and quality control of misfolded cystic fibrosis transmembrane conductance regulator at multiple levels.

Saxena A, Banasavadi-Siddegowda YK, Fan Y, Bhattacharya S, Roy G, Giovannucci DR, Frizzell RA, Wang X.

J Biol Chem. 2012 Jun 1;287(23):19158-70. doi: 10.1074/jbc.M111.297580. Epub 2012 Apr 13.

9.

Degradation of CFTR by the ubiquitin-proteasome pathway.

Ward CL, Omura S, Kopito RR.

Cell. 1995 Oct 6;83(1):121-7.

10.

Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator.

Younger JM, Chen L, Ren HY, Rosser MF, Turnbull EL, Fan CY, Patterson C, Cyr DM.

Cell. 2006 Aug 11;126(3):571-82.

11.

Interference with ubiquitination in CFTR modifies stability of core glycosylated and cell surface pools.

Lee S, Henderson MJ, Schiffhauer E, Despanie J, Henry K, Kang PW, Walker D, McClure ML, Wilson L, Sorscher EJ, Zeitlin PL.

Mol Cell Biol. 2014 Jul;34(14):2554-65.

12.

RNF185 is a novel E3 ligase of endoplasmic reticulum-associated degradation (ERAD) that targets cystic fibrosis transmembrane conductance regulator (CFTR).

El Khouri E, Le Pavec G, Toledano MB, Delaunay-Moisan A.

J Biol Chem. 2013 Oct 25;288(43):31177-91. doi: 10.1074/jbc.M113.470500. Epub 2013 Sep 9.

13.

SUMOylation Modulates CFTR Biogenesis: Is the Pathway Druggable?

Ahner A, Frizzell RA.

Curr Drug Targets. 2015;16(9):965-75. Review.

PMID:
26028049
14.

Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.

Chung WJ, Goeckeler-Fried JL, Havasi V, Chiang A, Rowe SM, Plyler ZE, Hong JS, Mazur M, Piazza GA, Keeton AB, White EL, Rasmussen L, Weissman AM, Denny RA, Brodsky JL, Sorscher EJ.

PLoS One. 2016 Oct 12;11(10):e0163615. doi: 10.1371/journal.pone.0163615. eCollection 2016.

16.

BAG-1 stabilizes mutant F508del-CFTR in a ubiquitin-like-domain-dependent manner.

Mendes F, Farinha CM, Felício V, Alves PC, Vieira I, Amaral MD.

Cell Physiol Biochem. 2012;30(5):1120-33. doi: 10.1159/000343303. Epub 2012 Oct 5.

18.

RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response.

Poulsen SL, Hansen RK, Wagner SA, van Cuijk L, van Belle GJ, Streicher W, Wikström M, Choudhary C, Houtsmuller AB, Marteijn JA, Bekker-Jensen S, Mailand N.

J Cell Biol. 2013 Jun 10;201(6):797-807. doi: 10.1083/jcb.201212075.

19.

Ubiquitin C-terminal hydrolase-L1 protects cystic fibrosis transmembrane conductance regulator from early stages of proteasomal degradation.

Henderson MJ, Vij N, Zeitlin PL.

J Biol Chem. 2010 Apr 9;285(15):11314-25. doi: 10.1074/jbc.M109.044057. Epub 2010 Feb 10.

20.

Sumo E2 enzyme UBC9 is required for efficient protein quality control in cardiomyocytes.

Gupta MK, Gulick J, Liu R, Wang X, Molkentin JD, Robbins J.

Circ Res. 2014 Sep 26;115(8):721-9. doi: 10.1161/CIRCRESAHA.115.304760. Epub 2014 Aug 5.

Supplemental Content

Support Center